| Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1 H Nishizawa, M Matsumoto, T Shindo, D Saigusa, H Kato, K Suzuki, ... Journal of Biological Chemistry 295 (1), 69-82, 2020 | 208 | 2020 |
| Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal H Nishizawa, M Yamanaka, K Igarashi The FEBS Journal 290 (7), 1688-1704, 2023 | 105 | 2023 |
| BACH1 promotes pancreatic cancer metastasis by repressing epithelial genes and enhancing epithelial–mesenchymal transition M Sato, M Matsumoto, Y Saiki, M Alam, H Nishizawa, M Rokugo, ... Cancer research 80 (6), 1279-1292, 2020 | 97 | 2020 |
| Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells H Nishizawa, M Matsumoto, G Chen, Y Ishii, K Tada, M Onodera, H Kato, ... Cell Death & Disease 12 (4), 332, 2021 | 79 | 2021 |
| The transcription factor BACH1 at the crossroads of cancer biology: from epithelial–mesenchymal transition to ferroptosis K Igarashi, H Nishizawa, Y Saiki, M Matsumoto Journal of Biological Chemistry 297 (3), 2021 | 74 | 2021 |
| Pemetrexed and cisplatin for advanced non-squamous non-small cell lung cancer in Japanese patients: phase II study Y Kawano, F Ohyanagi, N Yanagitani, K Kudo, A Horiike, A Tanimoto, ... Anticancer research 33 (8), 3327-3333, 2013 | 40 | 2013 |
| Infection perturbs Bach2-and Bach1-dependent erythroid lineage ‘choice’to cause anemia H Kato, A Itoh-Nakadai, M Matsumoto, Y Ishii, M Watanabe-Matsui, ... Nature immunology 19 (10), 1059-1070, 2018 | 39 | 2018 |
| Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR J Li, H Shima, H Nishizawa, M Ikeda, A Brydun, M Matsumoto, H Kato, ... Biochemical Journal 475 (5), 981-1002, 2018 | 26 | 2018 |
| Congenital sideroblastic anemia model due to ALAS2 mutation is susceptible to ferroptosis K Ono, T Fujiwara, K Saito, H Nishizawa, N Takahashi, C Suzuki, T Ochi, ... Scientific Reports 12 (1), 9024, 2022 | 22 | 2022 |
| Bach1‐mediated suppression of p53 is inhibited by p19ARF independently of MDM2 H Nishizawa, K Ota, Y Dohi, T Ikura, K Igarashi Cancer Science 103 (5), 897-903, 2012 | 17 | 2012 |
| Phase II study of docetaxel-plus-bevacizumab combination therapy in patients previously treated for advanced non-squamous non-small cell lung cancer F Ohyanagi, N Yanagitani, K Kudo, Y Kawano, T Sakatani, A Tanimoto, ... Anticancer Research 34 (9), 5153-5158, 2014 | 16 | 2014 |
| Ferroptosis model system by the re-expression of BACH1 R Irikura, H Nishizawa, K Nakajima, M Yamanaka, G Chen, K Tanaka, ... The Journal of Biochemistry 174 (3), 239-252, 2023 | 12 | 2023 |
| BACH1 expression is promoted by tank binding kinase 1 (TBK1) in pancreatic cancer cells to increase iron and reduce the expression of E-cadherin L Liu, M Matsumoto, M Matsui-Watanabe, K Ochiai, BKK Callens, ... Antioxidants 11 (8), 1460, 2022 | 10 | 2022 |
| TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and-independent mechanisms without relying on heme and FBXO22 L Liu, M Matsumoto, M Watanabe-Matsui, T Nakagawa, Y Nagasawa, ... International Journal of Molecular Sciences 25 (8), 4141, 2024 | 6 | 2024 |
| BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion H Nishizawa, M Matsumoto, M Yamanaka, R Irikura, K Nakajima, K Tada, ... Cell reports 43 (7), 2024 | 5 | 2024 |
| Iron in Cancer Progression: Does BACH1 Promote Metastasis by Altering Iron Homeostasis? K Igarashi, H Nishizawa, M Matsumoto Metabolism and Epigenetic Regulation: Implications in Cancer, 67-80, 2022 | 2 | 2022 |
| Pancreatic Cancer SF Facts The Lancet 403 (10446), 2807-2817, 2018 | 2 | 2018 |
| A phase II study of carboplatin and pemetrexed for elderly patients with advanced non-squamous non-small cell lung cancer H Nishizawa, A Horiike, R Saito, F Ohyanagi, K Kudo, N Yanagitani, ... Cancer Treatment and Research Communications 9, 100-105, 2016 | 1 | 2016 |
| Phase II trial of bevacizumab, cisplatin, and pemetrexed in Japanese patients with advanced nonsquamous non-small cell lung cancer. N Yanagitani, F Ohyanagi, H Nishizawa, H Gyotoku, T Uenami, ... Journal of Clinical Oncology 32 (15_suppl), e19135-e19135, 2014 | 1 | 2014 |
| Intracellular biliverdin dynamics during ferroptosis K Nakajima, H Nishizawa, G Chen, S Tsuge, M Yamanaka, M Kiyohara, ... The Journal of Biochemistry 176 (6), 472-483, 2024 | | 2024 |
Kazuhiko IgarashiDepartment of Biochemistry, Tohoku University Graduate School of MedicineVahvistettu sähköpostiosoite verkkotunnuksessa med.tohoku.ac.jp
