Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies DT Rodgers, M Mazagova, EN Hampton, Y Cao, NS Ramadoss, IR Hardy, ... Proceedings of the National Academy of Sciences 113 (4), E459-E468, 2016 | 456 | 2016 |
Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic EN Chin, C Yu, VF Vartabedian, Y Jia, M Kumar, AM Gamo, W Vernier, ... Science 369 (6506), 993-999, 2020 | 383 | 2020 |
Redirection of genetically engineered CAR-T cells using bifunctional small molecules MS Kim, JSY Ma, H Yun, Y Cao, JY Kim, V Chi, D Wang, A Woods, ... Journal of the American Chemical Society 137 (8), 2832-2835, 2015 | 197 | 2015 |
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis J Janes, ME Young, E Chen, NH Rogers, S Burgstaller-Muehlbacher, ... Proceedings of the National Academy of Sciences 115 (42), 10750-10755, 2018 | 190 | 2018 |
c-Kit expression identifies cardiovascular precursors in the neonatal heart YN Tallini, KS Greene, M Craven, A Spealman, M Breitbach, J Smith, ... Proceedings of the National Academy of Sciences 106 (6), 1808-1813, 2009 | 167 | 2009 |
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions MA Bakowski, N Beutler, KC Wolff, MG Kirkpatrick, E Chen, TTH Nguyen, ... Nature communications 12 (1), 3309, 2021 | 113 | 2021 |
Adenoviral Delivery of VEGF121 Early in Pregnancy Prevents Spontaneous Development of Preeclampsia in BPH/5 Mice AK Woods, DS Hoffmann, CJ Weydert, SD Butler, Y Zhou, RV Sharma, ... Hypertension 57 (1), 94-102, 2011 | 111 | 2011 |
A small molecule inhibits deregulated NRF2 transcriptional activity in cancer MJ Bollong, H Yun, L Sherwood, AK Woods, LL Lairson, PG Schultz ACS chemical biology 10 (10), 2193-2198, 2015 | 99 | 2015 |
Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory S Viaud, JSY Ma, IR Hardy, EN Hampton, B Benish, L Sherwood, ... Proceedings of the National Academy of Sciences 115 (46), E10898-E10906, 2018 | 95 | 2018 |
Development of a chimeric antigen receptor targeting C-type lectin-like molecule-1 for human acute myeloid leukemia E Laborda, M Mazagova, S Shao, X Wang, H Quirino, AK Woods, ... International journal of molecular sciences 18 (11), 2259, 2017 | 82 | 2017 |
A novel piperazine-based drug lead for cryptosporidiosis from the medicines for malaria venture open-access malaria box RS Jumani, K Bessoff, MS Love, P Miller, EE Stebbins, JE Teixeira, ... Antimicrobial Agents and Chemotherapy 62 (4), 10.1128/aac. 01505-17, 2018 | 67 | 2018 |
HSP90 inhibition enhances cancer immunotherapy by modulating the surface expression of multiple immune checkpoint proteins RB Zavareh, SH Spangenberg, A Woods, F Martínez-Peña, LL Lairson Cell chemical biology 28 (2), 158-168. e5, 2021 | 64 | 2021 |
Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery PY Yang, H Zou, E Chao, L Sherwood, V Nunez, M Keeney, ... Proceedings of the National Academy of Sciences 113 (15), 4140-4145, 2016 | 61 | 2016 |
Decidual Cox2 inhibition improves fetal and maternal outcomes in a preeclampsia-like mouse model JL Sones, J Cha, AK Woods, A Bartos, CY Heyward, HE Lob, CE Isroff, ... JCI insight 1 (3), e75351, 2016 | 60 | 2016 |
Targeted delivery of an anti-inflammatory PDE4 inhibitor to immune cells via an antibody–drug conjugate S Yu, AD Pearson, RKV Lim, DT Rodgers, S Li, HB Parker, M Weglarz, ... Molecular Therapy 24 (12), 2078-2089, 2016 | 57 | 2016 |
Design of potent and proteolytically stable oxyntomodulin analogs A Muppidi, H Zou, PY Yang, E Chao, L Sherwood, V Nunez, AK Woods, ... ACS chemical biology 11 (2), 324-328, 2016 | 48 | 2016 |
Small molecule selectively suppresses MYC transcription in cancer cells C Bouvard, SM Lim, J Ludka, N Yazdani, AK Woods, AK Chatterjee, ... Proceedings of the National Academy of Sciences 114 (13), 3497-3502, 2017 | 45 | 2017 |
Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections MA Bakowski, RK Shiroodi, R Liu, J Olejniczak, B Yang, K Gagaring, ... Science translational medicine 11 (491), eaav3523, 2019 | 43 | 2019 |
Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists T Liu, Y Zhang, Y Liu, Y Wang, H Jia, M Kang, X Luo, D Caballero, ... Proceedings of the National Academy of Sciences 112 (5), 1356-1361, 2015 | 34 | 2015 |
Amelioration of severe psoriasis with psoriatic arthritis for 20 years after allogeneic haematopoietic stem cell transplantation AC Woods, MJ Mant Annals of the rheumatic diseases 65 (5), 697-697, 2006 | 32 | 2006 |