Seuraa
Luke Jostins
Luke Jostins
University of Oxford
Vahvistettu sähköpostiosoite verkkotunnuksessa sanger.ac.uk
Nimike
Viittaukset
Viittaukset
Vuosi
A map of human genome variation from population scale sequencing
1000 Genomes Project Consortium
Nature 467 (7319), 1061, 2010
89092010
An integrated map of genetic variation from 1,092 human genomes
1000 Genomes Project Consortium
Nature 491 (7422), 56, 2012
86282012
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
5599*2012
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ...
Nature genetics 42 (12), 1118-1125, 2010
32042010
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ...
Nature genetics 47 (9), 979-986, 2015
27252015
A systematic survey of loss-of-function variants in human protein-coding genes
DG MacArthur, S Balasubramanian, A Frankish, N Huang, J Morris, ...
Science 335 (6070), 823-828, 2012
14262012
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
KM De Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ...
Nature genetics 49 (2), 256-261, 2017
14232017
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ...
The Lancet 387 (10014), 156-167, 2016
8882016
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ...
Science 343 (6175), 1246949, 2014
8552014
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
D Ellinghaus, L Jostins, SL Spain, A Cortes, J Bethune, B Han, YR Park, ...
Nature genetics 48 (5), 510-518, 2016
7952016
Fine-mapping inflammatory bowel disease loci to single-variant resolution
H Huang, M Fang, L Jostins, M Umićević Mirkov, G Boucher, ...
Nature 547 (7662), 173-178, 2017
6682017
Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel
O Delaneau, J Marchini
Nature communications 5 (1), 3934, 2014
4732014
Class II HLA interactions modulate genetic risk for multiple sclerosis
Nature genetics 47 (10), 1107-1113, 2015
4432015
Integrative annotation of variants from 1092 humans: application to cancer genomics
E Khurana, Y Fu, V Colonna, XJ Mu, HM Kang, T Lappalainen, A Sboner, ...
Science 342 (6154), 1235587, 2013
4192013
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
SG Ji, BD Juran, S Mucha, T Folseraas, L Jostins, E Melum, N Kumasaka, ...
Nature genetics 49 (2), 269-273, 2017
3692017
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis
JZ Liu, MA Almarri, DJ Gaffney, GF Mells, L Jostins, HJ Cordell, SJ Ducker, ...
Nature genetics 44 (10), 1137-1141, 2012
3202012
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease
JC Lee, D Biasci, R Roberts, RB Gearry, JC Mansfield, T Ahmad, ...
Nature genetics 49 (2), 262-268, 2017
2842017
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
CA Dendrou, A Cortes, L Shipman, HG Evans, KE Attfield, L Jostins, ...
Science translational medicine 8 (363), 363ra149-363ra149, 2016
2622016
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
KA Hunt, V Mistry, NA Bockett, T Ahmad, M Ban, JN Barker, JC Barrett, ...
Nature 498 (7453), 232-235, 2013
2442013
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ...
Cell 185 (5), 916-938. e58, 2022
2422022
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Artikkelit 1–20