| Pharmacological brake-release of mRNA translation enhances cognitive memory C Sidrauski, D Acosta-Alvear, A Khoutorsky, P Vedantham, BR Hearn, ... elife 2, e00498, 2013 | 699 | 2013 |
| Autism-related deficits via dysregulated eIF4E-dependent translational control CG Gkogkas, A Khoutorsky, I Ran, E Rampakakis, T Nevarko, ... Nature 493 (7432), 371-377, 2013 | 601 | 2013 |
| Translation deregulation in human disease S Tahmasebi, A Khoutorsky, MB Mathews, N Sonenberg Nature Reviews Molecular Cell Biology 19 (12), 791-807, 2018 | 245 | 2018 |
| Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain OK Melemedjian, MN Asiedu, DV Tillu, R Sanoja, J Yan, A Lark, ... Molecular pain 7, 1744-8069-7-70, 2011 | 235 | 2011 |
| Metformin ameliorates core deficits in a mouse model of fragile X syndrome I Gantois, A Khoutorsky, J Popic, A Aguilar-Valles, E Freemantle, R Cao, ... Nature medicine 23 (6), 674-677, 2017 | 226 | 2017 |
| Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes CG Gkogkas, A Khoutorsky, R Cao, SM Jafarnejad, M Prager-Khoutorsky, ... Cell reports 9 (5), 1742-1755, 2014 | 211 | 2014 |
| Reactivation of stalled polyribosomes in synaptic plasticity TE Graber, S Hébert-Seropian, A Khoutorsky, A David, JW Yewdell, ... Proceedings of the National Academy of Sciences 110 (40), 16205-16210, 2013 | 191 | 2013 |
| Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling R Cao, B Robinson, H Xu, C Gkogkas, A Khoutorsky, T Alain, A Yanagiya, ... Neuron 79 (4), 712-724, 2013 | 170 | 2013 |
| Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver C Chaveroux, LJ Eichner, CR Dufour, A Shatnawi, A Khoutorsky, ... Cell metabolism 17 (4), 586-598, 2013 | 166 | 2013 |
| The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain JK Moy, A Khoutorsky, MN Asiedu, BJ Black, JL Kuhn, ... Journal of Neuroscience 37 (31), 7481-7499, 2017 | 146 | 2017 |
| Unique interweaved microtubule scaffold mediates osmosensory transduction via physical interaction with TRPV1 M Prager-Khoutorsky, A Khoutorsky, CW Bourque Neuron 83 (4), 866-878, 2014 | 131 | 2014 |
| Translational control mechanisms in persistent pain A Khoutorsky, TJ Price Trends in neurosciences 41 (2), 100-114, 2018 | 124 | 2018 |
| Nociceptor translational profiling reveals the Ragulator-Rag GTPase complex as a critical generator of neuropathic pain S Megat, PR Ray, JK Moy, TF Lou, P Barragán-Iglesias, Y Li, G Pradhan, ... Journal of Neuroscience 39 (3), 393-411, 2019 | 119 | 2019 |
| Epiregulin and EGFR interactions are involved in pain processing LJ Martin, SB Smith, A Khoutorsky, CA Magnussen, A Samoshkin, ... The Journal of clinical investigation 127 (9), 3353-3366, 2017 | 115 | 2017 |
| eIF2α controls memory consolidation via excitatory and somatostatin neurons V Sharma, R Sood, A Khlaifia, MJ Eslamizade, TY Hung, D Lou, ... Nature 586 (7829), 412-416, 2020 | 114 | 2020 |
| Microglia-mediated degradation of perineuronal nets promotes pain S Tansley, N Gu, AU Guzmán, W Cai, C Wong, KC Lister, E Muñoz-Pino, ... Science 377 (6601), 80-86, 2022 | 107 | 2022 |
| mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK OK Melemedjian, A Khoutorsky, RE Sorge, J Yan, MN Asiedu, A Valdez, ... PAIN® 154 (7), 1080-1091, 2013 | 107 | 2013 |
| Single-cell RNA sequencing reveals time-and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain S Tansley, S Uttam, A Ureña Guzmán, M Yaqubi, A Pacis, M Parisien, ... Nature communications 13 (1), 843, 2022 | 101 | 2022 |
| Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2 S Tahmasebi, SM Jafarnejad, IS Tam, T Gonatopoulos-Pournatzis, ... Proceedings of the National Academy of Sciences 113 (44), 12360-12367, 2016 | 85 | 2016 |
| Metformin for treatment of fragile X syndrome and other neurological disorders I Gantois, J Popic, A Khoutorsky, N Sonenberg Annual review of medicine 70 (1), 167-181, 2019 | 84 | 2019 |
Nahum SonenbergGilman Cheney Professor in BiochemistryVahvistettu sähköpostiosoite verkkotunnuksessa mcgill.ca
