Integration of oxygen signaling at the consensus HRE RH Wenger, DP Stiehl, G Camenisch Science Signaling 2005 (306), re12, 2005 | 1329 | 2005 |
MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300 N Sang, DP Stiehl, J Bohensky, I Leshchinsky, V Srinivas, J Caro Journal of Biological Chemistry 278 (16), 14013-14019, 2003 | 485 | 2003 |
Normoxic induction of the hypoxia-inducible factor 1α by insulin and interleukin-1β involves the phosphatidylinositol 3-kinase pathway DP Stiehl, W Jelkmann, RH Wenger, T Hellwig-Bürgel FEBS letters 512 (1), 157-162, 2002 | 401 | 2002 |
Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels DP Stiehl, R Wirthner, J Köditz, P Spielmann, G Camenisch, RH Wenger Journal of Biological Chemistry 281 (33), 23482-23491, 2006 | 351 | 2006 |
Review: hypoxia-inducible factor-1 (HIF-1): a novel transcription factor in immune reactions T Hellwig-Bürgel, DP Stiehl, AE Wagner, E Metzen, W Jelkmann Journal of interferon & cytokine research 25 (6), 297-310, 2005 | 342 | 2005 |
Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element E Metzen, D Stiehl, K Doege, J Marxsen, T Hellwig-burgel, W Jelkmann Biochem. J 387, 711-717, 2005 | 270 | 2005 |
Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor J Köditz, J Nesper, M Wottawa, DP Stiehl, G Camenisch, C Franke, ... Blood, The Journal of the American Society of Hematology 110 (10), 3610-3617, 2007 | 258 | 2007 |
The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability S Barth, J Nesper, PA Hasgall, R Wirthner, KJ Nytko, F Edlich, ... Molecular and cellular biology 27 (10), 3758-3768, 2007 | 143 | 2007 |
Human nephrosclerosis triggers a hypoxia-related glomerulopathy MA Neusser, MT Lindenmeyer, AG Moll, S Segerer, I Edenhofer, K Sen, ... The American journal of pathology 176 (2), 594-607, 2010 | 114 | 2010 |
Dexamethasone impairs hypoxia-inducible factor-1 function AE Wagner, G Huck, DP Stiehl, W Jelkmann, T Hellwig-Bürgel Biochemical and biophysical research communications 372 (2), 336-340, 2008 | 113 | 2008 |
Non-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG–EGFR/ErbB4 autocrine loop DP Stiehl, MR Bordoli, I Abreu-Rodríguez, K Wollenick, P Schraml, ... Oncogene 31 (18), 2283-2297, 2011 | 97 | 2011 |
Prolyl-4-hydroxylase PHD2-and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis MR Bordoli, DP Stiehl, L Borsig, G Kristiansen, S Hausladen, P Schraml, ... Oncogene 30 (5), 548-560, 2010 | 90 | 2010 |
Vitamin C is dispensable for oxygen sensing in vivo KJ Nytko, N Maeda, P Schläfli, P Spielmann, RH Wenger, DP Stiehl Blood 117 (20), 5485-5493, 2011 | 88 | 2011 |
2-year outcomes of ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW extension study): prospective … N Marlow, A Stahl, D Lepore, A Fielder, JD Reynolds, Q Zhu, ... The Lancet Child & Adolescent Health 5 (10), 698-707, 2021 | 84 | 2021 |
Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events S Lehmann, DP Stiehl, M Honer, M Dominietto, R Keist, I Kotevic, ... Proceedings of the National Academy of Sciences 106 (33), 14004-14009, 2009 | 75 | 2009 |
Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation DP Stiehl, DM Fath, D Liang, Y Jiang, N Sang Cancer research 67 (5), 2256-2264, 2007 | 75 | 2007 |
Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1α-deficient mouse embryonic fibroblasts R Wirthner, S Wrann, K Balamurugan, RH Wenger, DP Stiehl Carcinogenesis 29 (12), 2306-2316, 2008 | 67 | 2008 |
Identification and functional characterization of pVHL-dependent cell surface proteins in renal cell carcinoma G Boysen, D Bausch-Fluck, CR Thoma, AM Nowicka, DP Stiehl, I Cima, ... Neoplasia 14 (6), 535-IN17, 2012 | 60 | 2012 |
Induction of the hypoxia-inducible factor system by low levels of heat shock protein 90 inhibitors NO Ibrahim, T Hahn, C Franke, DP Stiehl, R Wirthner, RH Wenger, ... Cancer research 65 (23), 11094-11100, 2005 | 58 | 2005 |
Endogenous Myoglobin in Breast Cancer Is Hypoxia-inducible by Alternative Transcription and Functions to Impair Mitochondrial Activity G Kristiansen, J Hu, D Wichmann, DP Stiehl, M Rose, J Gerhardt, ... Journal of Biological Chemistry 286 (50), 43417-43428, 2011 | 57 | 2011 |