| Structural basis for ligand promiscuity in cytochrome P450 3A4 M Ekroos, T Sjögren Proceedings of the National Academy of Sciences 103 (37), 13682-13687, 2006 | 894 | 2006 |
| Resting Memory CD8+ T Cells are Hyperreactive to Antigenic Challenge In Vitro M Pihlgren, PM Dubois, M Tomkowiak, T Sjögren, J Marvel The Journal of experimental medicine 184 (6), 2141-2152, 1996 | 299 | 1996 |
| 2-thioxanthines are mechanism-based inactivators of myeloperoxidase that block oxidative stress during inflammation AK Tidén, T Sjögren, M Svensson, A Bernlind, R Senthilmohan, ... Journal of Biological Chemistry 286 (43), 37578-37589, 2011 | 181 | 2011 |
| Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily T Sjögren, J Nord, M Ek, P Johansson, G Liu, S Geschwindner Proceedings of the National Academy of Sciences 110 (10), 3806-3811, 2013 | 139 | 2013 |
| Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold CK Wang, SH Hu, JL Martin, T Sjogren, J Hajdu, L Bohlin, P Claeson, ... Journal of Biological Chemistry 284 (16), 10672-10683, 2009 | 132 | 2009 |
| Potent reversible inhibition of myeloperoxidase by aromatic hydroxamates LV Forbes, T Sjögren, F Auchère, DW Jenkins, B Thong, D Laughton, ... Journal of Biological Chemistry 288 (51), 36636-36647, 2013 | 122 | 2013 |
| Structural and functional characterization of a specific antidote for ticagrelor A Buchanan, P Newton, S Pehrsson, T Inghardt, T Antonsson, ... Blood, The Journal of the American Society of Hematology 125 (22), 3484-3490, 2015 | 104 | 2015 |
| Structure-based ligand design to overcome CYP inhibition in drug discovery projects G Brändén, T Sjögren, V Schnecke, Y Xue Drug discovery today 19 (7), 905-911, 2014 | 103 | 2014 |
| Analyzing protein functions in four dimensions J Hajdu, R Neutze, T Sjögren, K Edman, A Szöke, RC Wilmouth, ... nature structural biology 7 (11), 1006-1012, 2000 | 102 | 2000 |
| Discovery of Disubstituted Imidazo[4,5-b]pyridines and Purines as Potent TrkA Inhibitors ZHJ Wang T, Lamb ML, Block MH, Davies AM, Han Y, Hoffmann E, Ioannidis S ... ACS Med Chem Lett., 2012 | 54 | 2012 |
| Quantum Mechanical Interpretation of Nitrite Reduction by Cytochrome cd1 Nitrite Reductase from Paracoccus pantotrophus G Ranghino, E Scorza, T Sjögren, PA Williams, M Ricci, J Hajdu Biochemistry 39 (36), 10958-10966, 2000 | 54 | 2000 |
| Defining Redox State of X-Ray Crystal Structures by Single-Crystal Ultraviolet–Visible Microspectrophotometry CM Wilmot, T Sjögren, GH Carlsson, GI Berglund, J Hajdu Methods in enzymology 353, 301-318, 2002 | 46 | 2002 |
| Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1 JA Douthwaite, S Sridharan, C Huntington, J Hammersley, R Marwood, ... MAbs 7 (1), 152-166, 2015 | 45 | 2015 |
| Structure of the Bound Dioxygen Species in the Cytochrome Oxidase Reaction of Cytochrome cd1Nitrite Reductase T Sjögren, J Hajdu Journal of Biological Chemistry 276 (16), 13072-13076, 2001 | 45 | 2001 |
| FragMAX: the fragment-screening platform at the MAX IV Laboratory GMA Lima, VO Talibov, E Jagudin, C Sele, M Nyblom, W Knecht, ... Biological Crystallography 76 (8), 771-777, 2020 | 41 | 2020 |
| Structure and kinetic properties of Paracoccus pantotrophus cytochrome cd1 nitrite reductase with the d1 heme active site ligand tyrosine 25 replaced by serine EHJ Gordon, T Sjögren, M Löfqvist, CD Richter, JWA Allen, ... Journal of Biological Chemistry 278 (14), 11773-11781, 2003 | 41 | 2003 |
| Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation O Fjellström, J Deinum, T Sjögren, C Johansson, S Geschwindner, ... Journal of Biological Chemistry 288 (2), 873-885, 2013 | 38 | 2013 |
| Protein crystallography in a vapour stream: data collection, reaction initiation and intermediate trapping in naked hydrated protein crystals T Sjögren, G Carlsson, G Larsson, A Hajdu, C Andersson, H Pettersson, ... Applied Crystallography 35 (1), 113-116, 2002 | 34 | 2002 |
| The Structure of an Alternative Form ofParacoccus pantotrophus Cytochromecd 1 Nitrite Reductase T Sjögren, J Hajdu Journal of Biological Chemistry 276 (31), 29450-29455, 2001 | 33 | 2001 |
| Discovery of AZD4831, a mechanism-based irreversible inhibitor of myeloperoxidase, as a potential treatment for heart failure with preserved ejection fraction T Inghardt, T Antonsson, C Ericsson, D Hovdal, P Johannesson, ... Journal of Medicinal Chemistry 65 (17), 11485-11496, 2022 | 29 | 2022 |
