Auspicious role of the steroidal heterocyclic derivatives as a platform for anti-cancer drugs MA Tantawy, MS Nafie, GA Elmegeed, IAI Ali Bioorganic chemistry 73, 128-146, 2017 | 109 | 2017 |
Triaryl dicationic DNA minor-groove binders with antioxidant activity display cytotoxicity and induce apoptosis in breast cancer MS Nafie, K Arafa, NK Sedky, AA Alakhdar, RK Arafa Chemico-biological interactions 324, 109087, 2020 | 92 | 2020 |
Screening of different drug design tools to predict the mode of action of steroidal derivatives as anti-cancer agents MS Nafie, MA Tantawy, GA Elmgeed Steroids 152, 108485, 2019 | 91 | 2019 |
Discovery of novel pyrazolo [3, 4-b] pyridine scaffold-based derivatives as potential PIM-1 kinase inhibitors in breast cancer MCF-7 cells MS Nafie, AM Amer, AK Mohamed, ES Tantawy Bioorganic & Medicinal Chemistry 28 (24), 115828, 2020 | 85 | 2020 |
Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[b]Thiophene-3-Carboxylate: Synthesis, In Vitro … EM Gad, MS Nafie, EH Eltamany, MSAG Hammad, A Barakat, ATA Boraei Molecules 25 (11), 2523, 2020 | 80 | 2020 |
Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches ES Tantawy, AM Amer, EK Mohamed, MM Abd Alla, MS Nafie Journal of Molecular Structure 1210, 128013, 2020 | 75 | 2020 |
Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway SW Kattan, MS Nafie, GA Elmgeed, W Alelwani, M Badar, MA Tantawy The Journal of Steroid Biochemistry and Molecular Biology 198, 105604, 2020 | 65 | 2020 |
Synthesis, molecular modeling and anti-cancer evaluation of a series of quinazoline derivatives AI Khodair, MA Alsafi, MS Nafie Carbohydrate Research 486, 107832, 2019 | 64 | 2019 |
Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies MM Khalifa, AA Al-Karmalawy, EB Elkaeed, MS Nafie, MA Tantawy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 299-314, 2022 | 62 | 2022 |
Exploration of novel VEGFR2 tyrosine kinase inhibitors via design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer MS Nafie, ATA Boraei Bioorganic Chemistry 122, 105708, 2022 | 58 | 2022 |
Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches ATA Boraei, EH Eltamany, IAI Ali, SM Gebriel, MS Nafie Bioorganic Chemistry 111, 104877, 2021 | 56 | 2021 |
Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity HSA ElZahabi, MS Nafie, D Osman, NH Elghazawy, DH Soliman, ... European Journal of Medicinal Chemistry 222, 113609, 2021 | 49 | 2021 |
Chemical Profiling, Antioxidant, Cytotoxic Activities and Molecular Docking Simulation of Carrichtera annua DC. (Cruciferae) EE Eltamany, SS Elhady, HA Ahmed, JM Badr, AO Noor, SA Ahmed, ... Antioxidants 9 (12), 1286, 2020 | 42 | 2020 |
Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: in vitro, in vivo, molecular docking, molecular dynamics, and SAR studies MM Hammouda, AA Elmaaty, MS Nafie, M Abdel-Motaal, NS Mohamed, ... Bioorganic Chemistry 127, 105995, 2022 | 41 | 2022 |
Ligand-based design on the dog-bone-shaped BIBR1532 pharmacophoric features and synthesis of novel analogues as promising telomerase inhibitors with in vitro and in vivo … AA Al-Karmalawy, MS Nafie, MA Shaldam, AA Elmaaty, SA Antar, ... Journal of Medicinal Chemistry 66 (1), 777-792, 2022 | 40 | 2022 |
Novel Bis-Thiazole Derivatives: Synthesis and Potential Cytotoxic Activity Through Apoptosis With Molecular Docking Approaches KM Dawood, MA Raslan, AA Abbas, BE Mohamed, MH Abdellattif, ... Frontiers in Chemistry 9, 694870, 2021 | 39 | 2021 |
Antimicrobial and antiproliferative activities of novel synthesized 6‐(quinolin‐2‐ylthio) pyridine derivatives with molecular docking study as multi‐targeted JAK2/STAT3 inhibitors MS Nafie, S Mahgoub, AM Amer Chemical Biology & Drug Design 97 (3), 553-564, 2021 | 37 | 2021 |
Molecular insights into human transmembrane protease serine-2 (TMPS2) inhibitors against SARS-CoV2: homology modelling, molecular dynamics, and docking studies SM Kishk, RM Kishk, ASA Yassen, MS Nafie, NA Nemr, G ElMasry, ... Molecules 25 (21), 5007, 2020 | 36 | 2020 |
Discovery of hydrazide-based pyridazino [4, 5-b] indole scaffold as a new phosphoinositide 3-kinase (PI3K) inhibitor for breast cancer therapy AAM Sarhan, ATA Boraei, A Barakat, MS Nafie RSC advances 10 (33), 19534-19541, 2020 | 34 | 2020 |
Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition MS Nafie, SM Kishk, S Mahgoub, AM Amer Chemical Biology & Drug Design 99 (4), 547-560, 2022 | 33 | 2022 |