Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus PAB Wark, SL Johnston, F Bucchieri, R Powell, S Puddicombe, ... The Journal of experimental medicine 201 (6), 937-947, 2005 | 1553 | 2005 |
Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells FM Ashcroft, DE Harrison, SJH Ashcroft Nature 312 (5993), 446-448, 1984 | 1517 | 1984 |
Role of deficient type III interferon-λ production in asthma exacerbations M Contoli, SD Message, V Laza-Stanca, MR Edwards, PAB Wark, ... Nature medicine 12 (9), 1023-1026, 2006 | 1209 | 2006 |
Epithelial-mesenchymal interactions in the pathogenesis of asthma ST Holgate, DE Davies, PM Lackie, SJ Wilson, SM Puddicombe, ... Journal of allergy and clinical immunology 105 (2), 193-204, 2000 | 771 | 2000 |
Defective epithelial barrier function in asthma C Xiao, SM Puddicombe, S Field, J Haywood, V Broughton-Head, ... Journal of Allergy and Clinical immunology 128 (3), 549-556. e12, 2011 | 759 | 2011 |
Effect of bronchoconstriction on airway remodeling in asthma CL Grainge, LCK Lau, JA Ward, V Dulay, G Lahiff, S Wilson, S Holgate, ... New England Journal of Medicine 364 (21), 2006-2015, 2011 | 747 | 2011 |
Airway remodeling in asthma: new insights HS Nelson, DE Davies, J Wicks, RM Powell, SM Puddicombe, ST Holgate Journal of allergy and clinical immunology 111 (2), 215-225, 2003 | 744 | 2003 |
Involvement of the epidermal growth factor receptor in epithelial repair in asthma SM Puddicombe, R Polosa, A Richter, MT Krishna, PH Howarth, ... The FASEB Journal 14 (10), 1362-1374, 2000 | 696 | 2000 |
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations K Bønnelykke, P Sleiman, K Nielsen, E Kreiner-Møller, JM Mercader, ... Nature genetics 46 (1), 51-55, 2014 | 691 | 2014 |
Tumour necrosis factor (TNFα) as a novel therapeutic target in symptomatic corticosteroid dependent asthma PH Howarth, KS Babu, HS Arshad, L Lau, M Buckley, W McConnell, ... Thorax 60 (12), 1012-1018, 2005 | 667 | 2005 |
Leukocyte analysis and differentiation using high speed microfluidic single cell impedance cytometry D Holmes, D Pettigrew, CH Reccius, JD Gwyer, C van Berkel, J Holloway, ... Lab on a Chip 9 (20), 2881-2889, 2009 | 512 | 2009 |
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial PD Monk, RJ Marsden, VJ Tear, J Brookes, TN Batten, M Mankowski, ... The Lancet Respiratory Medicine 9 (2), 196-206, 2021 | 495 | 2021 |
Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease CH Wiegman, C Michaeloudes, G Haji, P Narang, CJ Clarke, KE Russell, ... Journal of Allergy and Clinical Immunology 136 (3), 769-780, 2015 | 485 | 2015 |
The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma LM Hamilton, C Torres‐Lozano, SM Puddicombe, A Richter, I Kimber, ... Clinical & Experimental Allergy 33 (2), 233-240, 2003 | 445 | 2003 |
Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD RA O’donnell, C Peebles, JA Ward, A Daraker, G Angco, P Broberg, ... Thorax 59 (10), 837-842, 2004 | 368 | 2004 |
The contribution of interleukin (IL)-4 and IL-13 to the epithelial–mesenchymal trophic unit in asthma A Richter, SM Puddicombe, JL Lordan, F Bucchieri, SJ Wilson, ... American journal of respiratory cell and molecular biology 25 (3), 385-391, 2001 | 368 | 2001 |
Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis F Bucchieri, SM Puddicombe, JL Lordan, A Richter, D Buchanan, ... American journal of respiratory cell and molecular biology 27 (2), 179-185, 2002 | 361 | 2002 |
The contribution of transforming growth factor-β and epidermal growth factor signalling to airway remodelling in chronic asthma C Boxall, ST Holgate, DE Davies European Respiratory Journal 27 (1), 208-229, 2006 | 350 | 2006 |
Epithelial–mesenchymal communication in the pathogenesis of chronic asthma ST Holgate, J Holloway, S Wilson, F Bucchieri, S Puddicombe, DE Davies Proceedings of the American Thoracic Society 1 (2), 93-98, 2004 | 323 | 2004 |
A new look at the pathogenesis of asthma ST Holgate, HS Arshad, GC Roberts, PH Howarth, P Thurner, DE Davies Clinical science 118 (7), 439-450, 2010 | 322 | 2010 |