Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance MS Svetlov, EA Syroegin, EV Aleksandrova, GC Atkinson, ST Gregory, ... Nature chemical biology 17 (4), 412-420, 2021 | 95 | 2021 |
Kinetics of drug–ribosome interactions defines the cidality of macrolide antibiotics MS Svetlov, N Vázquez-Laslop, AS Mankin Proceedings of the National Academy of Sciences 114 (52), 13673-13678, 2017 | 76 | 2017 |
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics B Beckert, EC Leroy, S Sothiselvam, LV Bock, MS Svetlov, M Graf, ... Nature Communications 12 (1), 4466, 2021 | 71 | 2021 |
High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition MS Svetlov, E Plessa, CW Chen, A Bougas, MG Krokidis, GP Dinos, ... Rna 25 (5), 600-606, 2019 | 67 | 2019 |
Effective cotranslational folding of firefly luciferase without chaperones of the Hsp70 family MS Svetlov, A Kommer, VA Kolb, AS Spirin Protein science 15 (2), 242-247, 2006 | 65 | 2006 |
Attenuation-based dual-fluorescent-protein reporter for screening translation inhibitors IA Osterman, IV Prokhorova, VO Sysoev, YV Boykova, OV Efremenkova, ... Antimicrobial agents and chemotherapy 56 (4), 1774-1783, 2012 | 51 | 2012 |
Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins MM Almutairi, MS Svetlov, DA Hansen, NF Khabibullina, D Klepacki, ... Nucleic acids research 45 (16), 9573-9582, 2017 | 35 | 2017 |
Context-specific action of macrolide antibiotics on the eukaryotic ribosome MS Svetlov, TO Koller, S Meydan, V Shankar, D Klepacki, N Polacek, ... Nature Communications 12 (1), 2803, 2021 | 31 | 2021 |
An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance KJY Wu, BIC Tresco, A Ramkissoon, EV Aleksandrova, EA Syroegin, ... Science 383 (6684), 721-726, 2024 | 30 | 2024 |
Conjugates of Amino Acids and Peptides with 5-O-Mycaminosyltylonolide and Their Interaction with the Ribosomal Exit Tunnel A Shishkina, G Makarov, A Tereshchenkov, G Korshunova, N Sumbatyan, ... Bioconjugate Chemistry 24 (11), 1861-1869, 2013 | 21 | 2013 |
Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A CW Chen, N Leimer, EA Syroegin, C Dunand, ZP Bulman, K Lewis, ... Nature Communications 14 (1), 4196, 2023 | 13 | 2023 |
A long-distance rRNA base pair impacts the ability of macrolide antibiotics to kill bacteria MS Svetlov, S Cohen, N Alsuhebany, N Vázquez-Laslop, AS Mankin Proceedings of the National Academy of Sciences 117 (4), 1971-1975, 2020 | 13 | 2020 |
Folding of the firefly luciferase polypeptide chain with the immobilized C terminus MS Svetlov, VA Kolb, AS Spirin Molecular Biology 41, 86-92, 2007 | 13 | 2007 |
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it EV Aleksandrova, KJY Wu, BIC Tresco, EA Syroegin, EE Killeavy, ... Nature Chemical Biology 20 (7), 867-876, 2024 | 11 | 2024 |
Peptidyl-tRNA hydrolase is the nascent chain release factor in bacterial ribosome-associated quality control MS Svetlov, CF Dunand, JA Nakamoto, GC Atkinson, HA Safdari, ... Molecular Cell 84 (4), 715-726. e5, 2024 | 9 | 2024 |
Ribosome-associated quality control in bacteria MS Svetlov Biochemistry (Moscow) 86, 942-951, 2021 | 7 | 2021 |
Trigger factor assists the refolding of heterodimeric but not monomeric luciferases OE Melkina, II Goryanin, IV Manukhov, AV Baranova, VA Kolb, MS Svetlov, ... Biochemistry (Moscow) 79, 62-68, 2014 | 6 | 2014 |
Non-stressful death of 23S rRNA mutant G2061C defective in puromycin reaction PV Sergiev, DV Lesnyak, DE Burakovsky, M Svetlov, VA Kolb, ... Journal of Molecular Biology 416 (5), 656-667, 2012 | 6 | 2012 |
New system for high-throughput search of the bacterial translation inhibitors I Osterman, IV Prokhorova, VO Sysoev, YV Boykova, OV Efremenkova, ... FEBS JOURNAL 280, 276-276, 2013 | | 2013 |