Seuraa
Eric Ortlund
Eric Ortlund
Emory University School of Medicine
Vahvistettu sähköpostiosoite verkkotunnuksessa emory.edu - Kotisivu
Nimike
Viittaukset
Viittaukset
Vuosi
Rapid generation of neutralizing antibody responses in COVID-19 patients
MS Suthar, MG Zimmerman, RC Kauffman, G Mantus, SL Linderman, ...
Cell Reports Medicine 1 (3), 2020
5872020
Glucocorticoid receptor control of transcription: precision and plasticity via allostery
ER Weikum, MT Knuesel, EA Ortlund, KR Yamamoto
Nature reviews Molecular cell biology 18 (3), 159-174, 2017
5182017
The nuclear receptor superfamily: A structural perspective
ER Weikum, X Liu, EA Ortlund
Protein Science 27 (11), 1876-1892, 2018
5172018
Crystal structure of an ancient protein: evolution by conformational epistasis
EA Ortlund, JT Bridgham, MR Redinbo, JW Thornton
Science 317 (5844), 1544-1548, 2007
5132007
An epistatic ratchet constrains the direction of glucocorticoid receptor evolution
JT Bridgham, EA Ortlund, JW Thornton
Nature 461 (7263), 515-519, 2009
4592009
The structure, function and evolution of proteins that bind DNA and RNA
WH Hudson, EA Ortlund
Nature reviews Molecular cell biology 15 (11), 749-760, 2014
4122014
Evolutionary history and metabolic insights of ancient mammalian uricases
JT Kratzer, MA Lanaspa, MN Murphy, C Cicerchi, CL Graves, PA Tipton, ...
Proceedings of the National Academy of Sciences 111 (10), 3763-3768, 2014
4022014
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
JW Blanchard, LA Akay, J Davila-Velderrain, D von Maydell, H Mathys, ...
Nature 611 (7937), 769-779, 2022
2912022
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
JM Lee, YK Lee, JL Mamrosh, SA Busby, PR Griffin, MC Pathak, ...
Nature 474 (7352), 506-510, 2011
2862011
Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
G Schaaf, EA Ortlund, KR Tyeryar, CJ Mousley, KE Ile, TA Garrett, J Ren, ...
Molecular cell 29 (2), 191-206, 2008
2762008
Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans
A Folick, HD Oakley, Y Yu, EH Armstrong, M Kumari, L Sanor, DD Moore, ...
Science 347 (6217), 83-86, 2015
2662015
Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor
JT Bridgham, GN Eick, C Larroux, K Deshpande, MJ Harms, ...
PLoS biology 8 (10), e1000497, 2010
2662010
The structural basis of direct glucocorticoid-mediated transrepression
WH Hudson, C Youn, EA Ortlund
Nature structural & molecular biology 20 (1), 53-58, 2013
2372013
Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
EA Ortlund, Y Lee, IH Solomon, JM Hager, R Safi, Y Choi, Z Guan, ...
Nature structural & molecular biology 12 (4), 357-363, 2005
2302005
Molecular transducers of physical activity consortium (MoTrPAC): mapping the dynamic responses to exercise
JA Sanford, CD Nogiec, ME Lindholm, JN Adkins, D Amar, S Dasari, ...
Cell 181 (7), 1464-1474, 2020
2192020
Identification of a lipid scrambling domain in ANO6/TMEM16F
K Yu, JM Whitlock, K Lee, EA Ortlund, Y Yuan Cui, HC Hartzell
elife 4, e06901, 2015
1952015
Evolution of minimal specificity and promiscuity in steroid hormone receptors
GN Eick, JK Colucci, MJ Harms, EA Ortlund, JW Thornton
PLoS genetics 8 (11), e1003072, 2012
1462012
Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway
EH Armstrong, D Goswami, PR Griffin, N Noy, EA Ortlund
Journal of Biological Chemistry 289 (21), 14941-14954, 2014
1452014
Hydrophobic environment is a key factor for the stability of thermophilic proteins
MM Gromiha, MC Pathak, K Saraboji, EA Ortlund, EA Gaucher
Proteins: Structure, Function, and Bioinformatics 81 (4), 715-721, 2013
1432013
Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module
AN McKeown, JT Bridgham, DW Anderson, MN Murphy, EA Ortlund, ...
Cell 159 (1), 58-68, 2014
1292014
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Artikkelit 1–20