Seuraa
Alexander Sebastian Hauser
Alexander Sebastian Hauser
University of Copenhagen
Vahvistettu sähköpostiosoite verkkotunnuksessa alumni.ku.dk - Kotisivu
Nimike
Viittaukset
Viittaukset
Vuosi
Trends in GPCR drug discovery: new agents, targets and indications
AS Hauser, MM Attwood, M Rask-Andersen, HB Schiöth, DE Gloriam
Nature reviews Drug discovery 16 (12), 829-842, 2017
26652017
Pharmacogenomics of GPCR drug targets
AS Hauser, S Chavali, I Masuho, LJ Jahn, KA Martemyanov, DE Gloriam, ...
Cell 172 (1), 41-54. e19, 2018
6762018
GPCRdb in 2018: adding GPCR structure models and ligands
G Pándy-Szekeres, C Munk, TM Tsonkov, S Mordalski, K Harpsøe, ...
Nucleic acids research 46 (D1), D440-D446, 2018
5792018
GPCRDB: an information system for G protein-coupled receptors
V Isberg, B Vroling, R van der Kant, K Li, G Vriend, D Gloriam
Nucleic acids research 42 (D1), D422-D425, 2013
5312013
Selectivity determinants of GPCR–G-protein binding
T Flock, AS Hauser, N Lund, DE Gloriam, S Balaji, MM Babu
Nature 545 (7654), 317-322, 2017
4062017
GPCRdb: the G protein‐coupled receptor database–an introduction
C Munk, V Isberg, S Mordalski, K Harpsøe, K Rataj, AS Hauser, P Kolb, ...
British Journal of Pharmacology 173 (14), 2195-2207, 2016
2482016
Discovery of human signaling systems: pairing peptides to G protein-coupled receptors
SR Foster, AS Hauser, L Vedel, RT Strachan, XP Huang, AC Gavin, ...
Cell 179 (4), 895-908. e21, 2019
2252019
GPCR activation mechanisms across classes and macro/microscales
AS Hauser, AJ Kooistra, C Munk, FM Heydenreich, DB Veprintsev, ...
Nature structural & molecular biology 28 (11), 879-888, 2021
2062021
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs
C Avet, A Mancini, B Breton, C Le Gouill, AS Hauser, C Normand, ...
elife 11, e74101, 2022
1802022
Common coupling map advances GPCR-G protein selectivity
AS Hauser, C Avet, C Normand, A Mancini, A Inoue, M Bouvier, ...
elife 11, e74107, 2022
1092022
LEADS-PEP: a benchmark data set for assessment of peptide docking performance
AS Hauser, B Windshügel
Journal of chemical information and modeling 56 (1), 188-200, 2016
972016
The G protein database, GproteinDb
G Pándy-Szekeres, M Esguerra, AS Hauser, J Caroli, C Munk, S Pilger, ...
Nucleic Acids Research 50 (D1), D518-D525, 2022
752022
Glaucoma clinical research: trends in treatment strategies and drug development
L Storgaard, TL Tran, JC Freiberg, AS Hauser, M Kolko
Frontiers in medicine 8, 733080, 2021
662021
Integrating structural and mutagenesis data to elucidate GPCR ligand binding
C Munk, K Harpsøe, AS Hauser, V Isberg, DE Gloriam
Current opinion in pharmacology 30, 51-58, 2016
592016
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and …
AC Nøhr, MA Shehata, AS Hauser, V Isberg, J Mokrosinski, KB Andersen, ...
Neurochemistry international 102, 105-113, 2017
442017
Selectivity landscape of 100 therapeutically relevant GPCR profiled by an effector translocation-based BRET platform
C Avet, A Mancini, B Breton, C Le Gouill, A Hauser, C Normand, ...
422020
Novel approaches leading towards peptide GPCR de‐orphanisation
AS Hauser, DE Gloriam, H Bräuner‐Osborne, SR Foster
British Journal of Pharmacology 177 (5), 961-968, 2020
392020
Receptor selectivity between the G proteins Gα12 and Gα13 is defined by a single leucine-to-isoleucine variation
AE Mackenzie, T Quon, LC Lin, AS Hauser, L Jenkins, A Inoue, AB Tobin, ...
The FASEB Journal 33 (4), 5005, 2019
352019
Ligand-directed bias of G protein signaling at the dopamine D2 receptor
E Von Moo, K Harpsøe, AS Hauser, I Masuho, H Bräuner-Osborne, ...
Cell chemical biology 29 (2), 226-238. e4, 2022
342022
Loss of function glucose-dependent insulinotropic polypeptide receptor variants are associated with alterations in BMI, bone strength and cardiovascular outcomes
HS Kizilkaya, KV Sørensen, CJ Kibsgaard, LS Gasbjerg, AS Hauser, ...
Frontiers in Cell and Developmental Biology 9, 749607, 2021
272021
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Artikkelit 1–20