Mutations of the BRAF gene in human cancer H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ... Nature 417 (6892), 949-954, 2002 | 13173 | 2002 |
Massive genomic rearrangement acquired in a single catastrophic event during cancer development PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ... cell 144 (1), 27-40, 2011 | 2735 | 2011 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 2511* | 2020 |
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website S Bamford, E Dawson, S Forbes, J Clements, R Pettett, A Dogan, ... British journal of cancer 91 (2), 355-358, 2004 | 1420 | 2004 |
IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours MF Amary, K Bacsi, F Maggiani, S Damato, D Halai, F Berisha, R Pollock, ... The Journal of pathology 224 (3), 334-343, 2011 | 1099 | 2011 |
Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a prospective, randomised study W Bartlett, JA Skinner, CR Gooding, RWJ Carrington, AM Flanagan, ... The Journal of Bone & Joint Surgery British Volume 87 (5), 640-645, 2005 | 998 | 2005 |
Intragenic ERBB2 kinase mutations in tumours P Stephens, C Hunter, G Bignell, S Edkins, H Davies, J Teague, ... Nature 431 (7008), 525-526, 2004 | 979 | 2004 |
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone S Behjati, PS Tarpey, N Presneau, S Scheipl, N Pillay, P Van Loo, ... Nature genetics 45 (12), 1479-1482, 2013 | 861 | 2013 |
Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas S Vujovic, S Henderson, N Presneau, E Odell, TS Jacques, R Tirabosco, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2006 | 639 | 2006 |
The advantages of targeted protein degradation over inhibition: an RTK case study GM Burslem, BE Smith, AC Lai, S Jaime-Figueroa, DC McQuaid, ... Cell chemical biology 25 (1), 67-77. e3, 2018 | 624 | 2018 |
Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort S Smeland, SS Bielack, J Whelan, M Bernstein, P Hogendoorn, MD Krailo, ... European journal of cancer 109, 36-50, 2019 | 586 | 2019 |
Somatic mutations of the protein kinase gene family in human lung cancer H Davies, C Hunter, R Smith, P Stephens, C Greenman, G Bignell, ... Cancer research 65 (17), 7591-7595, 2005 | 578 | 2005 |
Mammary and extramammary Paget's disease J Lloyd, AM Flanagan Journal of clinical pathology 53 (10), 742-749, 2000 | 554 | 2000 |
Kaposi sarcoma herpesvirus–induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma HW Wang, MWB Trotter, D Lagos, D Bourboulia, S Henderson, T Mäkinen, ... Nature genetics 36 (7), 687-693, 2004 | 536 | 2004 |
Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2 MF Amary, S Damato, D Halai, M Eskandarpour, F Berisha, F Bonar, ... Nature genetics 43 (12), 1262-1265, 2011 | 480 | 2011 |
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ... Science 345 (6196), 1251343, 2014 | 460 | 2014 |
COSMIC 2005 S Forbes, J Clements, E Dawson, S Bamford, T Webb, A Dogan, ... British journal of cancer 94 (2), 318-322, 2006 | 460 | 2006 |
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ... elife 3, e02935, 2014 | 428 | 2014 |
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer P Stephens, S Edkins, H Davies, C Greenman, C Cox, C Hunter, G Bignell, ... Nature genetics 37 (6), 590-592, 2005 | 417 | 2005 |
Sarcoma classification by DNA methylation profiling C Koelsche, D Schrimpf, D Stichel, M Sill, F Sahm, DE Reuss, M Blattner, ... Nature communications 12 (1), 498, 2021 | 401 | 2021 |