| Genes that mediate breast cancer metastasis to lung AJ Minn, GP Gupta, PM Siegel, PD Bos, W Shu, DD Giri, A Viale, ... Nature 436 (7050), 518-524, 2005 | 3551 | 2005 |
| A multigenic program mediating breast cancer metastasis to bone Y Kang, PM Siegel, W Shu, M Drobnjak, SM Kakonen, C Cordón-Cardo, ... Cancer cell 3 (6), 537-549, 2003 | 3206 | 2003 |
| Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 2809 | 2012 |
| Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer PM Siegel, J Massagué Nature Reviews Cancer 3 (11), 807-820, 2003 | 2204 | 2003 |
| AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo B Faubert, G Boily, S Izreig, T Griss, B Samborska, Z Dong, F Dupuy, ... Cell metabolism 17 (1), 113-124, 2013 | 1022 | 2013 |
| E2F4/5 and p107 as Smad cofactors linking the TGFβ receptor to c-myc repression CR Chen, Y Kang, PM Siegel, J Massagué Cell 110 (1), 19-32, 2002 | 690 | 2002 |
| Elevated expression of activated forms of Neu/ErbB‐2 and ErbB‐3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer PM Siegel, ED Ryan, RD Cardiff, WJ Muller The EMBO journal, 1999 | 606 | 1999 |
| PDK1-dependent metabolic reprogramming dictates metastatic potential in breast cancer F Dupuy, S Tabariès, S Andrzejewski, Z Dong, J Blagih, MG Annis, ... Cell metabolism 22 (4), 577-589, 2015 | 581 | 2015 |
| Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis PM Siegel, W Shu, RD Cardiff, WJ Muller, J Massagué Proceedings of the National Academy of Sciences 100 (14), 8430-8435, 2003 | 571 | 2003 |
| Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations XY Liu, N Gerges, A Korshunov, N Sabha, DA Khuong-Quang, ... Acta neuropathologica 124, 615-625, 2012 | 517 | 2012 |
| Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations M Dankner, AAN Rose, S Rajkumar, PM Siegel, IR Watson Oncogene 37 (24), 3183-3199, 2018 | 488 | 2018 |
| Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma AM Fontebasso, S Papillon-Cavanagh, J Schwartzentruber, H Nikbakht, ... Nature genetics 46 (5), 462-466, 2014 | 468 | 2014 |
| Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway RJ Lee, C Albanese, M Fu, M D'Amico, B Lin, G Watanabe, GK Haines III, ... Molecular and cellular biology 20 (2), 672-683, 2000 | 437 | 2000 |
| Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis ER Andrechek, WR Hardy, PM Siegel, MA Rudnicki, RD Cardiff, ... Proceedings of the National Academy of Sciences 97 (7), 3444-3449, 2000 | 314 | 2000 |
| Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity SK Muthuswamy, PM Siegel, DL Dankort, MA Webster, WJ Muller Molecular and cellular biology 14 (1), 735-743, 1994 | 302 | 1994 |
| Novel Activating Mutations in the neu Proto-oncogene Involved in Induction of Mammary Tumors PM Siegel, DL Dankort, WR Hardy, WJ Muller Molecular and cellular biology 14 (11), 7068-7077, 1994 | 298 | 1994 |
| Metabolic plasticity as a determinant of tumor growth and metastasis C Lehuédé, F Dupuy, R Rabinovitch, RG Jones, PM Siegel Cancer research 76 (18), 5201-5208, 2016 | 293 | 2016 |
| Reciprocal regulation of Neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo: implications for human breast cancer JA Engelman, RJ Lee, A Karnezis, DJ Bearss, M Webster, P Siegel, ... Journal of Biological Chemistry 273 (32), 20448-20455, 1998 | 282 | 1998 |
| PGC-1α promotes breast cancer metastasis and confers bioenergetic flexibility against metabolic drugs S Andrzejewski, E Klimcakova, RM Johnson, S Tabariès, MG Annis, ... Cell metabolism 26 (5), 778-787. e5, 2017 | 258 | 2017 |
| ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties AAN Rose, MG Annis, Z Dong, F Pepin, M Hallett, M Park, PM Siegel PloS one 5 (8), e12093, 2010 | 237 | 2010 |
