Seuraa
Fredrik Svensson
Fredrik Svensson
Cancer Research Horizons
Vahvistettu sähköpostiosoite verkkotunnuksessa cancer.org.uk
Nimike
Viittaukset
Viittaukset
Vuosi
LightGBM: An effective and scalable algorithm for prediction of chemical toxicity–application to the Tox21 and mutagenicity data sets
J Zhang, D Mucs, U Norinder, F Svensson
Journal of chemical information and modeling 59 (10), 4150-4158, 2019
1892019
Therapy for glioblastoma: is it working?
ED Zanders, F Svensson, DS Bailey
Drug discovery today 24 (5), 1193-1201, 2019
1282019
Virtual screening data fusion using both structure-and ligand-based methods
F Svensson, A Karlén, C Sköld
Journal of chemical information and modeling 52 (1), 225-232, 2012
1152012
eMolTox: prediction of molecular toxicity with confidence
C Ji, F Svensson, A Zoufir, A Bender
Bioinformatics 34 (14), 2508-2509, 2018
772018
Palladium (II)-catalyzed desulfitative synthesis of aryl ketones from sodium arylsulfinates and nitriles: Scope, limitations, and mechanistic studies
B Skillinghaug, C Skold, J Rydfjord, F Svensson, M Behrends, ...
The Journal of Organic Chemistry 79 (24), 12018-12032, 2014
752014
Conformal regression for quantitative structure–activity relationship modeling—quantifying prediction uncertainty
F Svensson, N Aniceto, U Norinder, I Cortes-Ciriano, O Spjuth, L Carlsson, ...
Journal of Chemical Information and Modeling 58 (5), 1132-1140, 2018
712018
Improving screening efficiency through iterative screening using docking and conformal prediction
F Svensson, U Norinder, A Bender
Journal of chemical information and modeling 57 (3), 439-444, 2017
702017
Computational chemistry on a budget: supporting drug discovery with limited resources: miniperspective
H Willems, S De Cesco, F Svensson
Journal of Medicinal Chemistry 63 (18), 10158-10169, 2020
682020
Modelling compound cytotoxicity using conformal prediction and PubChem HTS data
F Svensson, U Norinder, A Bender
Toxicology research 6 (1), 73-80, 2017
682017
Deep learning-based conformal prediction of toxicity
J Zhang, U Norinder, F Svensson
Journal of chemical information and modeling 61 (6), 2648-2657, 2021
622021
Changing the HTS paradigm: AI-driven iterative screening for hit finding
GHS Dreiman, M Bictash, PV Fish, L Griffin, F Svensson
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (2), 257-262, 2021
572021
TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation
L Magno, TD Bunney, E Mead, F Svensson, MN Bictash
Molecular Neurodegeneration 16, 1-16, 2021
482021
Orthologue chemical space and its influence on target prediction
LH Mervin, KC Bulusu, L Kalash, AM Afzal, F Svensson, MA Firth, I Barrett, ...
Bioinformatics 34 (1), 72-79, 2018
452018
Decarboxylative palladium (II)‐catalyzed synthesis of aryl amidines from aryl carboxylic acids: Development and mechanistic investigation
J Rydfjord, F Svensson, A Trejos, PJR Sjöberg, C Sköld, J Sävmarker, ...
Chemistry–A European Journal 19 (41), 13803-13810, 2013
452013
Carboxylesterase notum is a druggable target to modulate Wnt signaling
ED Bayle, F Svensson, BN Atkinson, D Steadman, NJ Willis, ...
Journal of Medicinal Chemistry 64 (8), 4289-4311, 2021
362021
AI is a viable alternative to high throughput screening: a 318-target study
Scientific reports 14 (1), 7526, 2024
342024
Inhibition of insulin‐regulated aminopeptidase (IRAP) by arylsulfonamides
SR Borhade, U Rosenström, J Sävmarker, T Lundbäck, ...
ChemistryOpen 3 (6), 256-263, 2014
332014
Toward a benchmarking data set able to evaluate ligand-and structure-based virtual screening using public HTS data
M Lindh, F Svensson, W Schaal, J Zhang, C Sköld, P Brandt, A Karlén
Journal of chemical information and modeling 55 (2), 343-353, 2015
292015
Theoretical and experimental investigation of palladium (II)-catalyzed decarboxylative addition of arenecarboxylic acid to nitrile
F Svensson, RS Mane, J Savmarker, M Larhed, C Skold
Organometallics 32 (2), 490-497, 2013
282013
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
AH Alghamdi, JC Munday, GD Campagnaro, D Gurvic, F Svensson, ...
Elife 9, e56416, 2020
262020
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Artikkelit 1–20