A yeast synthetic network for in vivo assessment of reverse-engineering and modeling approaches I Cantone, L Marucci, F Iorio, MA Ricci, V Belcastro, M Bansal, S Santini, ... Cell 137 (1), 172-181, 2009 | 443 | 2009 |
Designing minimal genomes using whole-cell models J Rees-Garbutt, O Chalkley, S Landon, O Purcell, L Marucci, C Grierson Nature communications 11 (1), 836, 2020 | 63 | 2020 |
BSim 2.0: an advanced agent-based cell simulator A Matyjaszkiewicz, G Fiore, F Annunziata, CS Grierson, NJ Savery, ... ACS synthetic biology 6 (10), 1969-1972, 2017 | 62 | 2017 |
How to turn a genetic circuit into a synthetic tunable oscillator, or a bistable switch L Marucci, DAW Barton, I Cantone, MA Ricci, MP Cosma, S Santini, ... PloS one 4 (12), e8083, 2009 | 62 | 2009 |
In-Silico Analysis and Implementation of a Multicellular Feedback Control Strategy in a Synthetic Bacterial Consortium G Fiore, A Matyjaszkiewicz, F Annunziata, C Grierson, NJ Savery, ... ACS Synthetic Biology 6 (3), 507-517, 2017 | 61 | 2017 |
Mathematical models of organoid cultures S Montes-Olivas, L Marucci, M Homer Frontiers in Genetics 10, 873, 2019 | 55 | 2019 |
Regulation of gene expression and signaling pathway activity in mammalian cells by automated microfluidics feedback control L Postiglione, S Napolitano, E Pedone, DL Rocca, F Aulicino, M Santorelli, ... ACS synthetic biology 7 (11), 2558-2565, 2018 | 53 | 2018 |
An Orthogonal Multi-input Integration System to Control Gene Expression in Escherichia coli F Annunziata, A Matyjaszkiewicz, G Fiore, CS Grierson, L Marucci, ... ACS synthetic biology 6 (10), 1816-1824, 2017 | 51 | 2017 |
A tunable dual-input system for on-demand dynamic gene expression regulation E Pedone, L Postiglione, F Aulicino, DL Rocca, S Montes-Olivas, ... Nature communications 10 (1), 4481, 2019 | 50 | 2019 |
β-catenin fluctuates in mouse ESCs and is essential for Nanog-mediated reprogramming of somatic cells to pluripotency L Marucci, E Pedone, U Di Vicino, B Sanuy-Escribano, M Isalan, ... Cell reports 8 (6), 1686-1696, 2014 | 50 | 2014 |
Construction and modelling of an inducible positive feedback loop stably integrated in a mammalian cell-line V Siciliano, F Menolascina, L Marucci, C Fracassi, I Garzilli, MN Moretti, ... PLoS computational biology 7 (6), e1002074, 2011 | 48 | 2011 |
In Vivo Feedback Control of an Antithetic Molecular-Titration Motif in Escherichia coli Using Microfluidics B Shannon, CG Zamora-Chimal, L Postiglione, D Salzano, CS Grierson, ... ACS Synthetic Biology 9 (10), 2617-2624, 2020 | 42 | 2020 |
Computer-aided whole-cell design: taking a holistic approach by integrating synthetic with systems biology L Marucci, M Barberis, J Karr, O Ray, PR Race, M de Souza Andrade, ... Frontiers in Bioengineering and Biotechnology 8, 942, 2020 | 41 | 2020 |
Bridging the gap between mechanistic biological models and machine learning surrogates IM Gherman, ZS Abdallah, W Pang, TE Gorochowski, CS Grierson, ... PLoS Computational Biology 19 (4), e1010988, 2023 | 37 | 2023 |
Nanog dynamics in mouse embryonic stem cells: results from systems biology approaches L Marucci Stem cells international 2017 (1), 7160419, 2017 | 37 | 2017 |
Canonical Wnt pathway controls mESC self-renewal through inhibition of spontaneous differentiation via β-Catenin/TCF/LEF functions F Aulicino, E Pedone, F Sottile, F Lluis, L Marucci, MP Cosma Stem Cell Reports 15 (3), 646-661, 2020 | 36 | 2020 |
Role of β-catenin activation levels and fluctuations in controlling cell fate E Pedone, L Marucci Genes 10 (2), 176, 2019 | 36 | 2019 |
Advanced medical micro-robotics for early diagnosis and therapeutic interventions D Zhang, TE Gorochowski, L Marucci, HT Lee, B Gil, B Li, S Hauert, ... Frontiers in Robotics and AI 9, 1086043, 2023 | 32 | 2023 |
Cheetah: a computational toolkit for cybergenetic control E Pedone, I De Cesare, CG Zamora-Chimal, D Haener, L Postiglione, ... ACS Synthetic Biology 10 (5), 979-989, 2021 | 30 | 2021 |
Toward engineering biosystems with emergent collective functions TE Gorochowski, S Hauert, JU Kreft, L Marucci, NR Stillman, TYD Tang, ... Frontiers in bioengineering and biotechnology 8, 705, 2020 | 29 | 2020 |