CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 S Herzig, F Long, US Jhala, S Hedrick, R Quinn, A Bauer, D Rudolph, ... Nature 413 (6852), 179-183, 2001 | 1748 | 2001 |
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells L Bordone, MC Motta, F Picard, A Robinson, US Jhala, J Apfeld, ... PLoS biology 4 (2), e31, 2006 | 954 | 2006 |
Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus MT Malecki, US Jhala, A Antonellis, L Fields, A Doria, T Orban, M Saad, ... Nature genetics 23 (3), 323-328, 1999 | 849 | 1999 |
cAMP promotes pancreatic β-cell survival via CREB-mediated induction of IRS2 US Jhala, G Canettieri, RA Screaton, RN Kulkarni, S Krajewski, J Reed, ... Genes & development 17 (13), 1575-1580, 2003 | 703 | 2003 |
PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance RN Kulkarni, US Jhala, JN Winnay, S Krajewski, M Montminy, CR Kahn The Journal of clinical investigation 114 (6), 828-836, 2004 | 321 | 2004 |
Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation C Serra, D Palacios, C Mozzetta, SV Forcales, I Morantte, M Ripani, ... Molecular cell 28 (2), 200-213, 2007 | 217 | 2007 |
Analysis of an activator: coactivator complex reveals an essential role for secondary structure in transcriptional activation D Parker, US Jhala, I Radhakrishnan, MB Yaffe, C Reyes, AI Shulman, ... Molecular cell 2 (3), 353-359, 1998 | 207 | 1998 |
Hormonal Regulation of an Islet-Specific Enhancer in the Pancreatic Homeobox Gene STF-1 S Sharma, US Jhala, T Johnson, K Ferreri, J Leonard, M Montminy Molecular and cellular biology 17 (5), 2598-2604, 1997 | 146 | 1997 |
Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo K Du, H Asahara, US Jhala, BL Wagner, M Montminy Molecular and cellular biology 20 (12), 4320-4327, 2000 | 121 | 2000 |
COP1 functions as a FoxO1 ubiquitin E3 ligase to regulate FoxO1-mediated gene expression S Kato, J Ding, E Pisck, US Jhala, K Du Journal of Biological Chemistry 283 (51), 35464-35473, 2008 | 106 | 2008 |
Proteomic analysis of protein palmitoylation in adipocytes W Ren, US Jhala, K Du Adipocyte 2 (1), 17-27, 2013 | 98 | 2013 |
Development of diabesity in mice with neuronal deletion of Shp2 tyrosine phosphatase M Krajewska, S Banares, EE Zhang, X Huang, M Scadeng, US Jhala, ... The American journal of pathology 172 (5), 1312-1324, 2008 | 80 | 2008 |
Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinases RK Humphrey, SM Yu, LE Flores, US Jhala Journal of Biological Chemistry 285 (5), 3406-3416, 2010 | 77 | 2010 |
Alterations in growth and apoptosis of insulin receptor substrate-1-deficient β-cells AM Hennige, U Ozcan, T Okada, US Jhala, M Schubert, MF White, ... American Journal of Physiology-Endocrinology and Metabolism 289 (2), E337-E346, 2005 | 57 | 2005 |
Rat hepatic glutaminase: identification of the full coding sequence and characterization of a functional promoter MI CHUNG-BOK, N Vincent, U Jhala, M Watford Biochemical Journal 324 (1), 193-200, 1997 | 57 | 1997 |
Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells RK Humphrey, CJ Newcomb, AY Shu-Mei, E Hao, D Yu, S Krajewski, ... Journal of Biological Chemistry 285 (29), 22426-22436, 2010 | 51 | 2010 |
Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb JJ Lancman, N Zvenigorodsky, KP Gates, D Zhang, K Solomon, ... Development 140 (13), 2669-2679, 2013 | 44 | 2013 |
LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development NK Vinckier, NA Patel, RJ Geusz, A Wang, J Wang, I Matta, AR Harrington, ... Nature communications 11 (1), 2082, 2020 | 37 | 2020 |
Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic β cell death RK Humphrey, SMA Yu, A Bellary, S Gonuguntla, M Yebra, US Jhala Journal of Biological Chemistry 288 (4), 2428-2440, 2013 | 26 | 2013 |
Correction: Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells L Bordone, MC Motta, F Picard, A Robinson, US Jhala, J Apfeld, ... Plos Biology 13 (12), e1002346, 2015 | 22 | 2015 |