Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP K Rittinger, PA Walker, JF Eccleston, K Nurmahomed, D Owen, E Laue, ... Nature 388 (6643), 693-697, 1997 | 370 | 1997 |
The biochemistry of ras p21 RJ Grand, D Owen Biochemical journal 279 (Pt 3), 609, 1991 | 257 | 1991 |
Structure of Cdc42 bound to the GTPase binding domain of PAK A Morreale, M Venkatesan, HR Mott, D Owen, D Nietlispach, PN Lowe, ... Nature structural biology 7 (5), 384-388, 2000 | 248 | 2000 |
Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK HR Mott, D Owen, D Nietlispach, PN Lowe, E Manser, L Lim, ED Laue Nature 399 (6734), 384-388, 1999 | 228 | 1999 |
Delineation of the Cdc42/Rac-binding domain of p21-activated kinase G Thompson, D Owen, PA Chalk, PN Lowe Biochemistry 37 (21), 7885-7891, 1998 | 197 | 1998 |
Structure of the cyclin-dependent kinase inhibitor p19Ink4d FY Luh, SJ Archer, PJ Domaille, BO Smith, D Owen, DH Brotherton, ... Nature 389 (6654), 999-1003, 1997 | 121 | 1997 |
The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes D Owen, LJ Campbell, K Littlefield, KA Evetts, Z Li, DB Sacks, PN Lowe, ... Journal of Biological Chemistry 283 (3), 1692-1704, 2008 | 95 | 2008 |
Residues in Cdc42 that specify binding to individual CRIB effector proteins D Owen, HR Mott, ED Laue, PN Lowe Biochemistry 39 (6), 1243-1250, 2000 | 95 | 2000 |
Structures of Ras superfamily effector complexes: What have we learnt in two decades? HR Mott, D Owen Critical reviews in biochemistry and molecular biology 50 (2), 85-133, 2015 | 93 | 2015 |
A novel protein expressed in mammalian cells undergoing apoptosis RJA Grand, AE Milner, T Mustoe, GD Johnson, D Owen, ML Grant, ... Experimental cell research 218 (2), 439-451, 1995 | 84 | 1995 |
Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1) D Owen, PN Lowe, D Nietlispach, CE Brosnan, DY Chirgadze, PJ Parker, ... Journal of Biological Chemistry 278 (50), 50578-50587, 2003 | 71 | 2003 |
The Rac1 Polybasic Region Is Required for Interaction with Its Effector PRK1*♦ R Modha, LJ Campbell, D Nietlispach, HR Buhecha, D Owen, HR Mott Journal of Biological Chemistry 283 (3), 1492-1500, 2008 | 69 | 2008 |
Class IA PI3K regulatory subunits: p110-independent roles and structures M Fox, HR Mott, D Owen Biochemical Society Transactions 48 (4), 1397-1417, 2020 | 67 | 2020 |
DNA sequence analysis of the imp UV protection and mutation operon of the plasmid TP110: identification of a third gene D Lodwick, D Owen, P Strike Nucleic acids research 18 (17), 5045-5050, 1990 | 65 | 1990 |
Structure of the sterile α Motif (SAM) domain of the saccharomyces cerevisiae mitogen-activated protein kinase pathway-modulating protein STE50 and analysis of its interaction … SJ Grimshaw, HR Mott, KM Stott, PR Nielsen, KA Evetts, LJ Hopkins, ... Journal of Biological Chemistry 279 (3), 2192-2201, 2004 | 57 | 2004 |
Structural Analysis of the SH3 Domain of β-PIX and Its Interaction with α-p21 Activated Kinase (PAK), HR Mott, D Nietlispach, KA Evetts, D Owen Biochemistry 44 (33), 10977-10983, 2005 | 55 | 2005 |
Cdc42 in actin dynamics: An ordered pathway governed by complex equilibria and directional effector handover JR Watson, D Owen, HR Mott Small GTPases 8 (4), 237-244, 2017 | 54 | 2017 |
Intrinsically disordered proteins and membranes: a marriage of convenience for cell signalling? J Cornish, SG Chamberlain, D Owen, HR Mott Biochemical Society Transactions 48 (6), 2669-2689, 2020 | 51 | 2020 |
Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding RB Fenwick, S Prasannan, LJ Campbell, D Nietlispach, KA Evetts, ... Biochemistry 48 (10), 2192-2206, 2009 | 48 | 2009 |
The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction RB Fenwick, LJ Campbell, K Rajasekar, S Prasannan, D Nietlispach, ... Structure 18 (8), 985-995, 2010 | 45 | 2010 |