Artikkelit, joihin on yleisen käytön mandaatti - Guy GeorgesLisätietoja
Saatavilla jossain: 35
SAbDab: the structural antibody database
J Dunbar, K Krawczyk, J Leem, T Baker, A Fuchs, G Georges, J Shi, ...
Nucleic acids research 42 (D1), D1140-D1146, 2014
Mandaatit: UK Engineering and Physical Sciences Research Council
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies
G Niederfellner, A Lammens, O Mundigl, GJ Georges, W Schaefer, ...
Blood, The Journal of the American Society of Hematology 118 (2), 358-367, 2011
Mandaatit: German Research Foundation
ABodyBuilder: Automated antibody structure prediction with data–driven accuracy estimation
J Leem, J Dunbar, G Georges, J Shi, CM Deane
MAbs 8 (7), 1259-1268, 2016
Mandaatit: UK Engineering and Physical Sciences Research Council
SAbPred: a structure-based antibody prediction server
J Dunbar, K Krawczyk, J Leem, C Marks, J Nowak, C Regep, G Georges, ...
Nucleic acids research 44 (W1), W474-W478, 2016
Mandaatit: UK Engineering and Physical Sciences Research Council
ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins
B Abanades, WK Wong, F Boyles, G Georges, A Bujotzek, CM Deane
Communications Biology 6 (1), 575, 2023
Mandaatit: UK Engineering and Physical Sciences Research Council
ABlooper: fast accurate antibody CDR loop structure prediction with accuracy estimation
B Abanades, G Georges, A Bujotzek, CM Deane
Bioinformatics 38 (7), 1877-1880, 2022
Mandaatit: UK Engineering and Physical Sciences Research Council
DNA-encoded library-derived DDR1 inhibitor prevents fibrosis and renal function loss in a genetic mouse model of Alport syndrome
H Richter, AL Satz, M Bedoucha, B Buettelmann, AC Petersen, ...
ACS chemical biology 14 (1), 37-49, 2018
Mandaatit: US Department of Defense, US National Institutes of Health
The H3 loop of antibodies shows unique structural characteristics
C Regep, G Georges, J Shi, B Popovic, CM Deane
Proteins: Structure, Function, and Bioinformatics 85 (7), 1311-1318, 2017
Mandaatit: UK Engineering and Physical Sciences Research Council
Sphinx: merging knowledge-based and ab initio approaches to improve protein loop prediction
C Marks, J Nowak, S Klostermann, G Georges, J Dunbar, J Shi, S Kelm, ...
Bioinformatics 33 (9), 1346-1353, 2017
Mandaatit: UK Engineering and Physical Sciences Research Council
A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability
TE Rawson, M Rüth, E Blackwood, D Burdick, L Corson, J Dotson, ...
Journal of medicinal chemistry 51 (15), 4465-4475, 2008
Mandaatit: US National Institutes of Health
Prediction of VH–VL domain orientation for antibody variable domain modeling
A Bujotzek, J Dunbar, F Lipsmeier, W Schäfer, I Antes, CM Deane, ...
Proteins: Structure, Function, and Bioinformatics 83 (4), 681-695, 2015
Mandaatit: UK Engineering and Physical Sciences Research Council
CDR-H3 loop ensemble in solution–conformational selection upon antibody binding
ML Fernández-Quintero, J Kraml, G Georges, KR Liedl
MAbs 11 (6), 1077-1088, 2019
Mandaatit: Austrian Science Fund
Length-independent structural similarities enrich the antibody CDR canonical class model
J Nowak, T Baker, G Georges, S Kelm, S Klostermann, J Shi, S Sridharan, ...
MAbs 8 (4), 751-760, 2016
Mandaatit: UK Engineering and Physical Sciences Research Council
Antibodies exhibit multiple paratope states influencing VH–VL domain orientations
ML Fernández-Quintero, ND Pomarici, BA Math, KB Kroell, F Waibl, ...
Communications biology 3 (1), 589, 2020
Mandaatit: Austrian Science Fund
Assessing developability early in the discovery process for novel biologics
ML Fernández-Quintero, A Ljungars, F Waibl, V Greiff, JT Andersen, ...
MAbs 15 (1), 2171248, 2023
Mandaatit: US National Science Foundation, US National Institutes of Health, Austrian …
Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope
WK Wong, SA Robinson, A Bujotzek, G Georges, AP Lewis, J Shi, ...
MAbs 13 (1), 1873478, 2021
Mandaatit: UK Engineering and Physical Sciences Research Council, UK Medical Research …
Comparison of hydrophobicity scales for predicting biophysical properties of antibodies
F Waibl, ML Fernández-Quintero, FS Wedl, H Kettenberger, G Georges, ...
Frontiers in Molecular Biosciences 9, 960194, 2022
Mandaatit: Austrian Science Fund
VH‐VL interdomain dynamics observed by computer simulations and NMR
ML Fernández‐Quintero, VJ Hoerschinger, LM Lamp, A Bujotzek, ...
Proteins: Structure, Function, and Bioinformatics 88 (7), 830-839, 2020
Mandaatit: Austrian Science Fund
SCALOP: sequence-based antibody canonical loop structure annotation
WK Wong, G Georges, F Ros, S Kelm, AP Lewis, B Taddese, J Leem, ...
Bioinformatics 35 (10), 1774-1776, 2019
Mandaatit: UK Engineering and Physical Sciences Research Council, UK Medical Research …
Antibody side chain conformations are position‐dependent
J Leem, G Georges, J Shi, CM Deane
Proteins: Structure, Function, and Bioinformatics 86 (4), 383-392, 2018
Mandaatit: UK Engineering and Physical Sciences Research Council, UK Medical Research …
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