Artikkelit, joihin on yleisen käytön mandaatti - Isabelle LucetLisätietoja
Ei saatavilla missään: 10
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL
JM Murphy, IS Lucet, JM Hildebrand, MC Tanzer, SN Young, P Sharma, ...
Biochemical Journal 457 (3), 369-377, 2014
Mandaatit: Australian Research Council, National Health and Medical Research Council …
The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain
K Chen, RCJ Dobson, IS Lucet, SN Young, FG Pearce, ME Blewitt, ...
Biochemical Journal 473 (12), 1733-1744, 2016
Mandaatit: US National Institutes of Health, Australian Research Council, National …
Potent inhibition of necroptosis by simultaneously targeting multiple effectors of the pathway
CL Pierotti, MC Tanzer, AV Jacobsen, JM Hildebrand, JM Garnier, ...
ACS Chemical Biology 15 (10), 2702-2713, 2020
Mandaatit: National Health and Medical Research Council, Australia
Techniques to examine nucleotide binding by pseudokinases
IS Lucet, JJ Babon, JM Murphy
Biochemical Society Transactions 41 (4), 975-980, 2013
Mandaatit: Australian Research Council, National Health and Medical Research Council …
Characterization of ligand binding to pseudokinases using a thermal shift assay
IS Lucet, JM Murphy
Kinase Signaling Networks, 91-104, 2017
Mandaatit: Australian Research Council, National Health and Medical Research Council …
An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant
UK Nivarthi, S Gras, L Kjer-Nielsen, R Berry, IS Lucet, JJ Miles, SL Tracy, ...
The Journal of Immunology 193 (11), 5402-5413, 2014
Mandaatit: Australian Research Council, National Health and Medical Research Council …
A structural perspective of the pseudokinome: defining the targetable space
IS Lucet, JM Murphy
Mandaatit: National Health and Medical Research Council, Australia
Production and crystallization of recombinant JAK proteins
IS Lucet, R Bamert
JAK-STAT Signalling: Methods and Protocols, 275-300, 2013
Mandaatit: Australian Research Council
Production and purification of the PEAK pseudokinases for structural and functional studies
O Patel, M Surudoi, W Dai, JM Hardy, MJ Roy, IS Lucet
Methods in Enzymology 667, 1-35, 2022
Mandaatit: National Health and Medical Research Council, Australia
DCLK1 induces a pro-tumorigenic phenotype to drive gastric cancer progression
S Afshar-Sterle, ALE Carli, R O’Keefe, J Tse, S Fischer, AI Azimpour, ...
Science Signaling 17 (854), eabq4888, 2024
Mandaatit: National Health and Medical Research Council, Australia
Saatavilla jossain: 50
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ...
Immunity 39 (3), 443-453, 2013
Mandaatit: National Health and Medical Research Council, Australia
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ...
Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014
Mandaatit: Australian Research Council, National Health and Medical Research Council …
The molecular basis of JAK/STAT inhibition by SOCS1
NPD Liau, A Laktyushin, IS Lucet, JM Murphy, S Yao, E Whitlock, ...
Nature communications 9 (1), 1558, 2018
Mandaatit: National Health and Medical Research Council, Australia
The molecular regulation of Janus kinase (JAK) activation
JJ Babon, IS Lucet, JM Murphy, NA Nicola, LN Varghese
Biochemical Journal 462 (1), 1-13, 2014
Mandaatit: US National Institutes of Health, Australian Research Council, National …
Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity
JJ Babon, NJ Kershaw, JM Murphy, LN Varghese, A Laktyushin, ...
Immunity 36 (2), 239-250, 2012
Mandaatit: US National Institutes of Health
SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition
NJ Kershaw, JM Murphy, NPD Liau, LN Varghese, A Laktyushin, ...
Nature structural & molecular biology 20 (4), 469-476, 2013
Mandaatit: US National Institutes of Health, Australian Research Council, National …
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
Mandaatit: US National Science Foundation, Bill & Melinda Gates Foundation, US National …
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties
JM Murphy, Q Zhang, SN Young, ML Reese, FP Bailey, PA Eyers, ...
Biochemical Journal 457 (2), 323-334, 2014
Mandaatit: US National Institutes of Health, Australian Research Council, National …
Differential recognition of CD1d-α-galactosyl ceramide by the Vβ8. 2 and Vβ7 semi-invariant NKT T cell receptors
DG Pellicci, O Patel, L Kjer-Nielsen, SS Pang, LC Sullivan, ...
Immunity 31 (1), 47-59, 2009
Mandaatit: US National Institutes of Health
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ...
Nature communications 9 (1), 2422, 2018
Mandaatit: Australian Research Council, National Health and Medical Research Council …
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