EM measurements define the dimensions of the “30-nm” chromatin fiber: evidence for a compact, interdigitated structure PJJ Robinson, L Fairall, VAT Huynh, D Rhodes Proceedings of the National Academy of Sciences 103 (17), 6506-6511, 2006 | 691 | 2006 |
Structural basis for the activation of PPARγ by oxidized fatty acids T Itoh, L Fairall, K Amin, Y Inaba, A Szanto, BL Balint, L Nagy, ... Nature structural & molecular biology 15 (9), 924-931, 2008 | 543 | 2008 |
Structure of HDAC3 bound to co-repressor and inositol tetraphosphate PJ Watson, L Fairall, GM Santos, JWR Schwabe Nature 481 (7381), 335-340, 2012 | 542 | 2012 |
The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition L Fairall, JWR Schwabe, L Chapman, JT Finch, D Rhodes Nature 366 (6454), 483-487, 1993 | 460 | 1993 |
A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death LS Dickens, RS Boyd, R Jukes-Jones, MA Hughes, GL Robinson, ... Molecular cell 47 (2), 291-305, 2012 | 428 | 2012 |
Class I HDACs share a common mechanism of regulation by inositol phosphates CJ Millard, PJ Watson, I Celardo, Y Gordiyenko, SM Cowley, ... Molecular cell 51 (1), 57-67, 2013 | 417 | 2013 |
Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2 L Fairall, L Chapman, H Moss, T de Lange, D Rhodes Molecular cell 8 (2), 351-361, 2001 | 330 | 2001 |
EXAFS study of the zinc-binding sites in the protein transcription factor IIIA GP Diakun, L Fairall, A Klug Nature 324 (6098), 698-699, 1986 | 322 | 1986 |
TRF1 binds a bipartite telomeric site with extreme spatial flexibility A Bianchi, RM Stansel, L Fairall, JD Griffith, D Rhodes, T De Lange The EMBO journal, 1999 | 318 | 1999 |
Co-operative and hierarchical binding of c-FLIP and caspase-8: a unified model defines how c-FLIP isoforms differentially control cell fate MA Hughes, IR Powley, R Jukes-Jones, S Horn, M Feoktistova, L Fairall, ... Molecular cell 61 (6), 834-849, 2016 | 310 | 2016 |
Aster proteins facilitate nonvesicular plasma membrane to ER cholesterol transport in mammalian cells J Sandhu, S Li, L Fairall, SG Pfisterer, JE Gurnett, X Xiao, TA Weston, ... Cell 175 (2), 514-529. e20, 2018 | 257 | 2018 |
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors JH Kalin, M Wu, AV Gomez, Y Song, J Das, D Hayward, N Adejola, M Wu, ... Nature communications 9 (1), 53, 2018 | 221 | 2018 |
Mapping of the sites of protection on a 5 s RNA gene by the xenopus transcription factor IIIA: A model for the interaction L Fairall, D Rhodes, A Klug Journal of molecular biology 192 (3), 577-591, 1986 | 210 | 1986 |
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery J Oberoi, L Fairall, PJ Watson, JC Yang, Z Czimmerer, T Kampmann, ... Nature structural & molecular biology 18 (2), 177-184, 2011 | 203 | 2011 |
Nuclear hormone receptor co-repressors: structure and function PJ Watson, L Fairall, JWR Schwabe Molecular and cellular endocrinology 348 (2), 440-449, 2012 | 200 | 2012 |
How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high‐resolution crystal structures R Court, L Chapman, L Fairall, D Rhodes EMBO reports 6 (1), 39-45, 2005 | 182 | 2005 |
Targeting class I histone deacetylases in a “complex” environment CJ Millard, PJ Watson, L Fairall, JWR Schwabe Trends in pharmacological sciences 38 (4), 363-377, 2017 | 181 | 2017 |
The structure of the core NuRD repression complex provides insights into its interaction with chromatin CJ Millard, N Varma, A Saleh, K Morris, PJ Watson, AR Bottrill, L Fairall, ... Elife 5, e13941, 2016 | 144 | 2016 |
Mechanism of crosstalk between the LSD1 demethylase and HDAC1 deacetylase in the CoREST complex Y Song, L Dagil, L Fairall, N Robertson, M Wu, TJ Ragan, CG Savva, ... Cell Reports 30 (8), 2699-2711. e8, 2020 | 125 | 2020 |
Sequence-specific DNA recognition by the myb-like domain of the human telomere binding protein TRF1: a model for the protein-DNA complex P König, L Fairall, D Rhodes Nucleic acids research 26 (7), 1731-1740, 1998 | 113 | 1998 |