Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2 E Lázár-Molnár, Q Yan, E Cao, U Ramagopal, SG Nathenson, SC Almo Proceedings of the National Academy of Sciences 105 (30), 10483-10488, 2008 | 292 | 2008 |
Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab UA Ramagopal, W Liu, SC Garrett-Thomson, JB Bonanno, Q Yan, ... Proceedings of the National Academy of Sciences 114 (21), E4223-E4232, 2017 | 178 | 2017 |
Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS WYC Huang, Q Yan, WC Lin, JK Chung, SD Hansen, SM Christensen, ... Proceedings of the National Academy of Sciences 113 (29), 8218-8223, 2016 | 131 | 2016 |
Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker Q Yan, T Barros, PR Visperas, S Deindl, TA Kadlecek, A Weiss, J Kuriyan Molecular and cellular biology 33 (11), 2188-2201, 2013 | 130 | 2013 |
Sequence, structure, function, immunity: structural genomics of costimulation K Chattopadhyay, E Lazar‐Molnar, Q Yan, R Rubinstein, C Zhan, ... Immunological reviews 229 (1), 356-386, 2009 | 122 | 2009 |
Understanding the impact of methionine oxidation on the biological functions of IgG1 antibodies using hydrogen/deuterium exchange mass spectrometry J Mo, Q Yan, CK So, T Soden, MJ Lewis, P Hu Analytical chemistry 88 (19), 9495-9502, 2016 | 109 | 2016 |
An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor NH Shah, Q Wang, Q Yan, D Karandur, TA Kadlecek, IR Fallahee, ... Elife 5, e20105, 2016 | 106 | 2016 |
NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family E Cao, UA Ramagopal, A Fedorov, E Fedorov, Q Yan, JW Lary, JL Cole, ... Immunity 25 (4), 559-570, 2006 | 91 | 2006 |
Structure of CD84 provides insight into SLAM family function Q Yan, VN Malashkevich, A Fedorov, E Fedorov, E Cao, JW Lary, JL Cole, ... Proceedings of the National Academy of Sciences 104 (25), 10583-10588, 2007 | 88 | 2007 |
Structure based prediction of asparagine deamidation propensity in monoclonal antibodies Q Yan, M Huang, MJ Lewis, P Hu MAbs 10 (6), 901-912, 2018 | 82 | 2018 |
Decoy strategies: the structure of TL1A: DcR3 complex C Zhan, Y Patskovsky, Q Yan, Z Li, U Ramagopal, H Cheng, M Brenowitz, ... Structure 19 (2), 162-171, 2011 | 82 | 2011 |
Quantitative analysis of glycation and its impact on antigen binding J Mo, R Jin, Q Yan, I Sokolowska, MJ Lewis, P Hu MAbs 10 (3), 406-415, 2018 | 44 | 2018 |
Biochemical and Structural Characterization of the Human TL1A Ectodomain, C Zhan, Q Yan, Y Patskovsky, Z Li, R Toro, A Meyer, H Cheng, ... Biochemistry 48 (32), 7636-7645, 2009 | 44 | 2009 |
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding PR Visperas, JA Winger, TM Horton, NH Shah, DJ Aum, A Tao, T Barros, ... Biochemical Journal 465 (1), 149-161, 2015 | 27 | 2015 |
Identification of inhibitors of the association of ZAP-70 with the T cell receptor by high-throughput screen PR Visperas, CG Wilson, JA Winger, Q Yan, K Lin, MR Arkin, A Weiss, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (3), 324-331, 2017 | 16 | 2017 |
Protein Assembly on Membrane Surface alters the Dynamical Spectrum of Downstream Signaling Reactions WYC Huang, Q Yan, WC Lin, JK Chung, SD Hansen, SM Christensen, ... Biophysical Journal 110 (3), 88a, 2016 | | 2016 |
Crystal structure of SLAM family members: implications for their costimulatory functions in T cell (88.9) Q Yan, V Malashkevich, E Cao, JW Lary, JL Cole, SG Nathenson, ... The Journal of Immunology 178 (1_Supplement), S140-S140, 2007 | | 2007 |