| Biogenesis and function of extracellular vesicles in cancer MP Bebelman, MJ Smit, DM Pegtel, SR Baglio Pharmacology & therapeutics 188, 1-11, 2018 | 857 | 2018 |
| Molecular pharmacological aspects of histamine receptors R Leurs, MJ Smit, H Timmerman Pharmacology & therapeutics 66 (3), 413-463, 1995 | 471 | 1995 |
| Identification of rat H3 receptor isoforms with different brain expression and signaling properties G Drutel, N Peitsaro, K Karlstedt, K Wieland, MJ Smit, H Timmerman, ... Molecular Pharmacology 59 (1), 1-8, 2001 | 375 | 2001 |
| Consensus on the role of human cytomegalovirus in glioblastoma K Dziurzynski, SM Chang, AB Heimberger, RF Kalejta, ... Neuro-oncology 14 (3), 246-255, 2012 | 368 | 2012 |
| Histamine H1-receptor activation of nuclear factor-κB: roles for Gβγ-and Gαq/11-subunits in constitutive and agonist-mediated signaling RA Bakker, SBJ Schoonus, MJ Smit, H Timmerman, R Leurs Molecular pharmacology 60 (5), 1133-1142, 2001 | 344 | 2001 |
| Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling FJ Verweij, MP Bebelman, CR Jimenez, JJ Garcia-Vallejo, H Janssen, ... Journal of Cell Biology 217 (3), 1129-1142, 2018 | 335 | 2018 |
| Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28 P Casarosa, RA Bakker, D Verzijl, M Navis, H Timmerman, R Leurs, ... Journal of Biological Chemistry 276 (2), 1133-1137, 2001 | 328 | 2001 |
| Pharmacological modulation of chemokine receptor function DJ Scholten, M Canals, D Maussang, L Roumen, MJ Smit, M Wijtmans, ... British journal of pharmacology 165 (6), 1617-1643, 2012 | 316 | 2012 |
| Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis D Maussang, D Verzijl, M Van Walsum, R Leurs, J Holl, O Pleskoff, ... Proceedings of the National Academy of Sciences 103 (35), 13068-13073, 2006 | 304 | 2006 |
| CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells S Jähnichen, C Blanchetot, D Maussang, M Gonzalez-Pajuelo, KY Chow, ... Proceedings of the National Academy of Sciences 107 (47), 20565-20570, 2010 | 288 | 2010 |
| Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors. MJ Smit, R Leurs, AE Alewijnse, J Blauw, GP van Nieuw Amerongen, ... Proceedings of the National Academy of Sciences 93 (13), 6802-6807, 1996 | 282 | 1996 |
| The effect of mutations in the dry motif on the constitutive activity and structural instability of the histamine h2receptor AE Alewijnse, H Timmerman, EH Jacobs, MJ Smit, E Roovers, ... Molecular pharmacology 57 (5), 890-898, 2000 | 271 | 2000 |
| HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6–STAT3 axis E Slinger, D Maussang, A Schreiber, M Siderius, A Rahbar, ... Science signaling 3 (133), ra58-ra58, 2010 | 251 | 2010 |
| CXCR3-mediated chemotaxis of human T cells is regulated by a Gi-and phospholipase C–dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase MJ Smit, P Verdijk, EMH van der Raaij-Helmer, M Navis, PJ Hensbergen, ... Blood 102 (6), 1959-1965, 2003 | 241 | 2003 |
| Pharmacogenomic and structural analysis of constitutive G protein–coupled receptor activity MJ Smit, HF Vischer, RA Bakker, A Jongejan, H Timmerman, L Pardo, ... Annu. Rev. Pharmacol. Toxicol. 47 (1), 53-87, 2007 | 220 | 2007 |
| Agonist-independent regulation of constitutively active G-protein-coupled receptors R Leurs, MJ Smit, AE Alewijnse, H Timmerman Trends in biochemical sciences 23 (11), 418-422, 1998 | 196 | 1998 |
| The human cytomegalovirus–encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2 D Maussang, E Langemeijer, CP Fitzsimons, M Stigter-van Walsum, ... Cancer research 69 (7), 2861-2869, 2009 | 194 | 2009 |
| Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Gαs stimulation Y Chen, A Harry, J Li, MJ Smit, X Bai, R Magnusson, JP Pieroni, G Weng, ... Proceedings of the National Academy of Sciences 94 (25), 14100-14104, 1997 | 193 | 1997 |
| Targeting chemokine receptors in chronic inflammatory diseases: an extensive review PJ Koelink, SA Overbeek, S Braber, P de Kruijf, G Folkerts, MJ Smit, ... Pharmacology & therapeutics 133 (1), 1-18, 2012 | 189 | 2012 |
| Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin N Hulsman, JP Medema, C Bos, A Jongejan, R Leurs, MJ Smit, ... Journal of medicinal chemistry 50 (10), 2424-2431, 2007 | 183 | 2007 |
