Applications of supercritical CO2 in the fabrication of polymer systems for drug delivery and tissue engineering OR Davies, AL Lewis, MJ Whitaker, H Tai, KM Shakesheff, SM Howdle Advanced drug delivery reviews 60 (3), 373-387, 2008 | 372 | 2008 |
Liver tissue engineering: a role for co-culture systems in modifying hepatocyte function and viability RNB Bhandari, LA Riccalton, AL Lewis, JR Fry, AH Hammond, ... Tissue engineering 7 (3), 345-357, 2001 | 253 | 2001 |
Sustained release hGH microsphere formulation produced by a novel supercritical fluid technology: in vivo studies F Jordan, A Naylor, CA Kelly, SM Howdle, A Lewis, L Illum Journal of Controlled Release 141 (2), 153-160, 2010 | 98 | 2010 |
Challenges in the delivery of peptide drugs: an industry perspective AL Lewis, J Richard Therapeutic Delivery 6 (2), 149-163, 2015 | 93 | 2015 |
Absorption of therapeutic agents across mucosal membranes or the skin L Illum, FM Jordan, AL Lewis US Patent 8,795,634, 2014 | 71 | 2014 |
Development and approval of rybelsus (oral semaglutide): ushering in a new era in peptide delivery AL Lewis, N McEntee, J Holland, A Patel Drug delivery and translational research 12 (1), 1-6, 2022 | 56 | 2022 |
CriticalSorb™: A novel efficient nasal delivery system for human growth hormone based on Solutol HS15 L Illum, F Jordan, AL Lewis Journal of controlled release 162 (1), 194-200, 2012 | 55 | 2012 |
Cataract surgery and subtype in a defined, older population: the SEECAT Project A Lewis, N Congdon, B Munoz, H Bowie, H Lai, P Chen, SK West British journal of ophthalmology 88 (12), 1512-1517, 2004 | 38 | 2004 |
Single shot tetanus vaccine manufactured by a supercritical fluid encapsulation technology AJ Baxendale, P Van Hooff, LG Durrant, I Spendlove, SM Howdle, ... International journal of pharmaceutics 413 (1-2), 147-154, 2011 | 33 | 2011 |
CriticalSorb™ promotes permeation of flux markers across isolated rat intestinal mucosae and Caco-2 monolayers DJ Brayden, VA Bzik, AL Lewis, L Illum Pharmaceutical research 29, 2543-2554, 2012 | 27 | 2012 |
Fatty acid binding protein is a major determinant of hepatic pharmacokinetics of palmitate and its metabolites DY Hung, FJ Burczynski, P Chang, A Lewis, PP Masci, GA Siebert, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 284 (3 …, 2003 | 27 | 2003 |
Nasal administration and plasma pharmacokinetics of parathyroid hormone peptide PTH 1-34 for the treatment of osteoporosis RG Pearson, T Masud, E Blackshaw, A Naylor, M Hinchcliffe, K Jeffery, ... Pharmaceutics 11 (6), 265, 2019 | 26 | 2019 |
In vitro and preclinical assessment of an intranasal spray formulation of parathyroid hormone PTH 1–34 for the treatment of osteoporosis AJ Williams, F Jordan, G King, AL Lewis, L Illum, T Masud, AC Perkins, ... International journal of pharmaceutics 535 (1-2), 113-119, 2018 | 24 | 2018 |
Supercritical fluid-mediated methods to encapsulate drugs: recent advances and new opportunities A Naylor, AL Lewis, L Illum Therapeutic Delivery 2 (12), 1551-1565, 2011 | 24 | 2011 |
CriticalSorb™: enabling systemic delivery of macromolecules via the nasal route AL Lewis, F Jordan, L Illum Drug delivery and translational research 3, 26-32, 2013 | 23 | 2013 |
Oral peptide delivery: technology landscape and current status LN Hassani, A Lewis, J Richard OnDrugDelivery 59, 12-17, 2015 | 22 | 2015 |
Formulation strategies for sustained release of proteins AL Lewis, L Illum Therapeutic delivery 1 (3), 457-479, 2010 | 15 | 2010 |
Stability of human growth hormone in supercritical carbon dioxide CA Kelly, SM Howdle, A Naylor, G Coxhill, LC Tye, L Illum, AL Lewis Journal of pharmaceutical sciences 101 (1), 56-67, 2012 | 13 | 2012 |
Intranasal human growth hormone (hGH) induces IGF-1 levels comparable with subcutaneous injection with lower systemic exposure to hGH in healthy volunteers AL Lewis, F Jordan, T Patel, K Jeffery, G King, M Savage, S Shalet, L Illum The Journal of Clinical Endocrinology & Metabolism 100 (11), 4364-4371, 2015 | 10 | 2015 |
Use of Resonant Acoustic Mixing Technology for Ultra-Low-Dose Blending in a Single-Step Mixing Process KA Frey, H Baker, DK Purcell, AL Lewis, DA Engers Pharmaceutical Research 41 (1), 165-183, 2024 | 5 | 2024 |