ER stress and the unfolded protein response in neurodegeneration C Hetz, S Saxena Nature Reviews Neurology 13, 477–491, 2017 | 901 | 2017 |
Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF S Pun, AF Santos, S Saxena, L Xu, P Caroni Nature neuroscience 9 (3), 408-419, 2006 | 747 | 2006 |
A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice S Saxena, E Cabuy, P Caroni Nature neuroscience 12 (5), 627-636, 2009 | 731 | 2009 |
Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration S Saxena, P Caroni Neuron 71 (1), 35-48, 2011 | 654 | 2011 |
Mechanisms of axon degeneration: from development to disease S Saxena, P Caroni Progress in neurobiology 83 (3), 174-191, 2007 | 328 | 2007 |
Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival S Saxena, F Roselli, K Singh, K Leptien, JP Julien, F Gros-Louis, P Caroni Neuron 80 (1), 80-96, 2013 | 309 | 2013 |
The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA S Saxena, C Bucci, J Weis, A Kruttgen Journal of neuroscience 25 (47), 10930-10940, 2005 | 212 | 2005 |
C9ORF72 regulates stress granule formation and its deficiency impairs stress granule assembly, hypersensitizing cells to stress N Maharjan, C Künzli, K Buthey, S Saxena Molecular neurobiology 54, 3062-3077, 2017 | 128 | 2017 |
Cloning of novel human SEC14p-like proteins: ligand binding and functional properties P Kempná, JM Zingg, R Ricciarelli, M Hierl, S Saxena, A Azzi Free Radical Biology and Medicine 34 (11), 1458-1472, 2003 | 114 | 2003 |
Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS A Filézac de L'Etang, N Maharjan, M Cordeiro Braña, C Ruegsegger, ... Nature neuroscience 18 (2), 227-238, 2015 | 109 | 2015 |
Proteostasis impairment in ALS C Ruegsegger, S Saxena Brain research 1648, 571-579, 2016 | 98 | 2016 |
Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking S Saxena, CL Howe, JM Cosgaya, P Steiner, H Hirling, JR Chan, J Weis, ... Molecular and Cellular Neuroscience 28 (3), 571-587, 2005 | 84 | 2005 |
Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ DM Stucki, C Ruegsegger, S Steiner, J Radecke, MP Murphy, B Zuber, ... Free Radical Biology and Medicine 97, 427-440, 2016 | 68 | 2016 |
Aberrant association of misfolded SOD1 with Na+/K+ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS C Ruegsegger, N Maharjan, A Goswami, A Filézac de L’Etang, J Weis, ... Acta neuropathologica 131, 427-451, 2016 | 60 | 2016 |
Neurotrophins and neurodegenerative diseases: receptors stuck in traffic? A Kruttgen, S Saxena, ME Evangelopoulos, J Weis Journal of Neuropathology & Experimental Neurology 62 (4), 340-350, 2003 | 60 | 2003 |
Emerging perspectives on dipeptide repeat proteins in C9ORF72 ALS/FTD A Schmitz, J Pinheiro Marques, I Oertig, N Maharjan, S Saxena Frontiers in cellular neuroscience 15, 637548, 2021 | 55 | 2021 |
Impaired mTORC1-dependent expression of homer-3 influences SCA1 pathophysiology C Ruegsegger, DM Stucki, S Steiner, N Angliker, J Radecke, E Keller, ... Neuron 89 (1), 129-146, 2016 | 53 | 2016 |
Slow waves promote sleep-dependent plasticity and functional recovery after stroke L Facchin, C Schöne, A Mensen, M Bandarabadi, F Pilotto, S Saxena, ... Journal of neuroscience 40 (45), 8637-8651, 2020 | 50 | 2020 |
Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology I Reichenstein, C Eitan, S Diaz-Garcia, G Haim, I Magen, A Siany, ... Science translational medicine 11 (523), eaav5264, 2019 | 46 | 2019 |
P2X1‐regulated IL‐22 secretion by innate lymphoid cells is required for efficient liver regeneration R Kudira, T Malinka, A Kohler, M Dosch, MG de Agüero, N Melin, ... Hepatology 63 (6), 2004-2017, 2016 | 42 | 2016 |