| Fundamental mechanisms of regulated cell death and implications for heart disease DP Del Re, D Amgalan, A Linkermann, Q Liu, RN Kitsis Physiological reviews 99 (4), 1765-1817, 2019 | 789 | 2019 |
| Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis R Miao, C Jiang, WY Chang, H Zhang, J An, F Ho, P Chen, H Zhang, ... Immunity 56 (11), 2523-2541. e8, 2023 | 140 | 2023 |
| A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy D Amgalan, TP Garner, R Pekson, XF Jia, M Yanamandala, V Paulino, ... Nature cancer 1 (3), 315-328, 2020 | 103 | 2020 |
| Small-molecule allosteric inhibitors of BAX TP Garner, D Amgalan, DE Reyna, S Li, RN Kitsis, E Gavathiotis Nature chemical biology 15 (4), 322-330, 2019 | 89 | 2019 |
| Grounding cardio-oncology in basic and clinical science J Moslehi, D Amgalan, RN Kitsis Circulation 136 (1), 3-5, 2017 | 35 | 2017 |
| SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy D Feng, D Amgalan, R Singh, J Wei, J Wen, TP Wei, TE McGraw, ... The Journal of Clinical Investigation 128 (9), 3941-3956, 2018 | 28 | 2018 |
| Troponin release following brief myocardial ischemia: apoptosis versus necrosis D Amgalan, R Pekson, RN Kitsis Basic to Translational Science 2 (2), 118-121, 2017 | 27 | 2017 |
| Death receptor signaling in the heart: cell survival, apoptosis, and necroptosis D Amgalan, Y Chen, RN Kitsis Circulation 136 (8), 743-746, 2017 | 26 | 2017 |
| A mouse model for the most common form of heart failure D Amgalan, RN Kitsis Nature 568 (7752), 324-325, 2019 | 21 | 2019 |
| An Akt3 splice variant lacking the serine 472 phosphorylation site promotes apoptosis and suppresses mammary tumorigenesis K Suyama, J Yao, H Liang, O Benard, OD Loudig, D Amgalan, ... Cancer research 78 (1), 103-114, 2018 | 21 | 2018 |
| Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease M Yu, C Tcheandjieu, A Georges, K Xiao, H Tejeda, C Dina, ... JCI insight 7 (3), 2022 | 16* | 2022 |
| Deciphering the impact of genomic variation on function Code of Conduct Committee (alphabetical by last name) Cody Sarah 33 Farrell ... Nature 633 (8028), 47-57, 2024 | 10 | 2024 |
| The impact of genomic variation on function (IGVF) consortium IGVF Consortium ArXiv, 2023 | 10 | 2023 |
| ATG16L1 autophagy pathway regulates BAX protein levels and programmed cell death F Chen, D Amgalan, RN Kitsis, JE Pessin, D Feng Journal of Biological Chemistry 295 (44), 15045-15053, 2020 | 10 | 2020 |
| Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes M Yu, M Aguirre, M Jia, K Gjoni, A Cordova-Palomera, C Munger, ... Circulation: Genomic and Precision Medicine 16 (3), 258-266, 2023 | 6 | 2023 |
| Genetic determinants of the interventricular septum are linked to ventricular septal defects and hypertrophic cardiomyopathy M Yu, AR Harper, M Aguirre, M Pittman, C Tcheandjieu, D Amgalan, ... Circulation: Genomic and Precision Medicine 16 (3), 207-215, 2023 | 5 | 2023 |
| Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart XR Ma, SD Conley, M Kosicki, D Bredikhin, R Cui, S Tran, MU Sheth, ... medRxiv, 2024.11. 20.24317557, 2024 | 1 | 2024 |
| Mapping enhancer-gene regulatory interactions from single-cell data MU Sheth, WL Qiu, XR Ma, AR Gschwind, E Jagoda, AS Tan, H Einarsson, ... bioRxiv, 2024.11. 23.624931, 2024 | 1 | 2024 |
| Variant-enhancer-gene mapping at the 9p21 locus in smooth muscle cells reveals new enhancer-gene pairs and mechanistic insights for coronary artery disease M Ramste, C Weldy, Q Zhao, A Ranta, D Li, D Sharma, J Monteiro, ... Circulation 150 (Suppl_1), A4142133-A4142133, 2024 | | 2024 |
| Small molecule bax inhibitors and uses thereof E Gavathiotis, RN Kitsis, TP Garner, D Amgalan, L Kirshenbaum, F Kopp US Patent App. 18/595,808, 2024 | | 2024 |