| Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei JA Stortz, TD Serafim, S Alsford, J Wilkes, F Fernandez-Cortes, ... PLoS pathogens 13 (7), e1006477, 2017 | 54 | 2017 |
| Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing EM Briggs, F Rojas, R McCulloch, KR Matthews, TD Otto Nature communications 12 (1), 5268, 2021 | 50 | 2021 |
| Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion E Briggs, K Crouch, L Lemgruber, C Lapsley, R McCulloch PLoS genetics 14 (12), e1007729, 2018 | 48 | 2018 |
| Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome E Briggs, G Hamilton, K Crouch, C Lapsley, R McCulloch Nucleic acids research 46 (22), 11789-11805, 2018 | 40 | 2018 |
| Trypanosoma brucei ribonuclease H2A is an essential R-loop processing enzyme whose loss causes DNA damage during transcription initiation and antigenic … E Briggs, K Crouch, L Lemgruber, G Hamilton, C Lapsley, R McCulloch Nucleic Acids Research 47 (17), 9180-9197, 2019 | 36 | 2019 |
| Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection JF Quintana, P Chandrasegaran, MC Sinton, EM Briggs, TD Otto, ... Nature communications 13 (1), 5752, 2022 | 35 | 2022 |
| Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes MS da Silva, GA Hovel-Miner, EM Briggs, MC Elias, R McCulloch PLoS pathogens 14 (11), e1007321, 2018 | 31 | 2018 |
| Read, write, adapt: challenges and opportunities during kinetoplastid genome replication JD Damasceno, CA Marques, J Black, E Briggs, R McCulloch Trends in Genetics 37 (1), 21-34, 2021 | 22 | 2021 |
| Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome J Faria, EM Briggs, JA Black, R McCulloch Current opinion in microbiology 70, 102209, 2022 | 18 | 2022 |
| Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation AZ Leal, M Schwebs, E Briggs, N Weisert, H Reis, L Lemgruber, K Luko, ... Nucleic acids research 48 (17), 9660-9680, 2020 | 16 | 2020 |
| Profiling the bloodstream form and procyclic form Trypanosoma brucei cell cycle using single-cell transcriptomics EM Briggs, CA Marques, GR Oldrieve, J Hu, TD Otto, KR Matthews Elife 12, e86325, 2023 | 13 | 2023 |
| Application of single-cell transcriptomics to kinetoplastid research EM Briggs, FSL Warren, KR Matthews, R McCulloch, TD Otto Parasitology 148 (10), 1223-1236, 2021 | 12 | 2021 |
| RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei MJ Girasol, M Krasilnikova, CA Marques, JD Damasceno, C Lapsley, ... Proceedings of the National Academy of Sciences 120 (48), e2309306120, 2023 | 10 | 2023 |
| The developmental hierarchy and scarcity of replicative slender trypanosomes in blood challenges their role in infection maintenance SD Larcombe, EM Briggs, N Savill, B Szoor, KR Matthews Proceedings of the National Academy of Sciences 120 (42), e2306848120, 2023 | 7 | 2023 |
| Paving the way: contributions of big data to apicomplexan and kinetoplastid research RS Kent, EM Briggs, BL Colon, C Alvarez, S Silva Pereira, M De Niz Frontiers in cellular and infection microbiology 12, 900878, 2022 | 6 | 2022 |
| Immunoprecipitation of RNA–DNA hybrid interacting proteins in Trypanosoma brucei reveals conserved and novel activities, including in the control of surface … MJ Girasol, EM Briggs, CA Marques, JM Batista, D Beraldi, R Burchmore, ... Nucleic Acids Research 51 (20), 11123-11141, 2023 | 5 | 2023 |
| TrAGEDy: Trajectory Alignment of Gene Expression Dynamics RF Laidlaw, EM Briggs, KR Matthews, R McCulloch, TD Otto bioRxiv, 2022.12. 21.521424, 2022 | 5 | 2022 |
| Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection. Nat. Commun. 13, 5752 JF Quintana, P Chandrasegaran, MC Sinton, EM Briggs, TD Otto, ... | 5 | 2022 |
| Integrative single cell and spatial transcriptomic analysis reveal reciprocal microglia-plasma cell crosstalk in the mouse brain during chronic Trypanosoma brucei infection JF Quintana, P Chandrasegaran, MC Sinton, E Briggs, TD Otto, R Heslop, ... bioRxiv, 2022.03. 25.485502, 2022 | 4 | 2022 |
| When is a slender not a slender? The cell-cycle arrest and scarcity of slender parasites challenges the role of bloodstream trypanosomes in infection maintenance SD Larcombe, EM Briggs, N Savill, B Szoor, KR Matthews bioRxiv, 2023.04. 06.535835, 2023 | 3 | 2023 |
