Suivre
Ian Humphreys
Ian Humphreys
PhD Student, Molecular & Cellular Biology, University of Washington
Adresse e-mail validée de uw.edu
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Computed structures of core eukaryotic protein complexes
IR Humphreys, J Pei, M Baek, A Krishnakumar, I Anishchenko, ...
Science 374 (6573), eabm4805, 2021
4662021
Generalized biomolecular modeling and design with RoseTTAFold All-Atom
R Krishna, J Wang, W Ahern, P Sturmfels, P Venkatesh, I Kalvet, GR Lee, ...
Science 384 (6693), eadl2528, 2024
3732024
A longitudinal assessment of host-microbe-parasite interactions resolves the zebrafish gut microbiome’s link to Pseudocapillaria tomentosa infection and pathology
CA Gaulke, ML Martins, VG Watral, IR Humphreys, ST Spagnoli, ML Kent, ...
Microbiome 7, 1-16, 2019
1022019
Efficient and accurate prediction of protein structure using RoseTTAFold2
M Baek, I Anishchenko, I Humphreys, Q Cong, D Baker, F DiMaio
bioRxiv, 2023.05. 24.542179, 2023
842023
Ecophylogenetics clarifies the evolutionary association between mammals and their gut microbiota
CA Gaulke, HK Arnold, IR Humphreys, SW Kembel, JP O’Dwyer, ...
MBio 9 (5), 10.1128/mbio. 01348-18, 2018
812018
Protein tertiary structure prediction and refinement using deep learning and Rosetta in CASP14
I Anishchenko, M Baek, H Park, N Hiranuma, DE Kim, J Dauparas, ...
Proteins: Structure, Function, and Bioinformatics 89 (12), 1722-1733, 2021
502021
Recent advances in predicting and modeling protein–protein interactions
J Durham, J Zhang, IR Humphreys, J Pei, Q Cong
Trends in biochemical sciences 48 (6), 527-538, 2023
382023
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
Y Wang, LA Gallagher, PA Andrade, A Liu, IR Humphreys, S Turkarslan, ...
Cell 186 (22), 4803-4817. e13, 2023
332023
ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A
X Wan, JD Serrill, IR Humphreys, M Tan, KL McPhail, IG Ganley, ...
Marine drugs 16 (3), 77, 2018
302018
Protein oligomer modeling guided by predicted interchain contacts in CASP14
M Baek, I Anishchenko, H Park, IR Humphreys, D Baker
Proteins: Structure, Function, and Bioinformatics 89 (12), 1824-1833, 2021
212021
Best practice for wildlife gut microbiome research: A comprehensive review of methodology for 16S rRNA gene investigations
L Combrink, IR Humphreys, Q Washburn, HK Arnold, K Stagaman, ...
Frontiers in Microbiology 14, 1092216, 2023
162023
An integrated gene catalog of the zebrafish gut microbiome reveals significant homology with mammalian microbiomes
CA Gaulke, LM Beaver, CR Armour, IR Humphreys, CL Barton, ...
BioRxiv, 2020.06. 15.153924, 2020
162020
Protein interactions in human pathogens revealed through deep learning
IR Humphreys, J Zhang, M Baek, Y Wang, A Krishnakumar, J Pei, ...
Nature Microbiology, 1-11, 2024
7*2024
The Marine-Derived Macrolactone Mandelalide A Is an Indirect Activator of AMPK
DR Mattos, X Wan, JD Serrill, MH Nguyen, IR Humphreys, B Viollet, ...
Marine Drugs 20 (7), 418, 2022
72022
Computational design of serine hydrolases
A Lauko, SJ Pellock, I Anischanka, KH Sumida, D Juergens, W Ahern, ...
bioRxiv, 2024
42024
Computing the Human Interactome
J Zhang, IR Humphreys, J Pei, J Kim, C Choi, R Yuan, J Durham, S Liu, ...
bioRxiv, 2024.10. 01.615885, 2024
32024
Rapid and accurate prediction of protein homo-oligomer symmetry with Seq2Symm
M Kshirsagar, A Meller, I Humphreys, S Sledzieski, Y Xu, R Dodhia, ...
Research Square, 2024
22024
Deep learning and coevolution reveal proteome-wide protein-protein interactions
I Humphreys
2024
Interspecies comparative metagenomics reveals correlated gut microbiome functional capacities among vertebrates
CA Gaulke, CR Armour, IR Humphreys, LM Beaver, CL Barton, L Carbone, ...
bioRxiv, 2020.06. 15.153320, 2020
2020
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