| Natural compounds as potential adjuvants to cancer therapy: Preclinical evidence SR Lin, CH Chang, CF Hsu, MJ Tsai, H Cheng, MK Leong, PJ Sung, ... British journal of pharmacology 177 (6), 1409-1423, 2020 | 378 | 2020 |
| Design, synthesis, and structure− activity relationship of pyridyl imidazolidinones: a novel class of potent and selective human enterovirus 71 inhibitors KS Shia, WT Li, CM Chang, MC Hsu, JH Chern, MK Leong, SN Tseng, ... Journal of medicinal chemistry 45 (8), 1644-1655, 2002 | 145 | 2002 |
| In silico approaches to identify polyphenol compounds as α-glucosidase and α-amylase inhibitors against type-II diabetes J Riyaphan, DC Pham, MK Leong, CF Weng Biomolecules 11 (12), 1877, 2021 | 100 | 2021 |
| A novel approach using pharmacophore ensemble/support vector machine (PhE/SVM) for prediction of hERG liability MK Leong Chemical research in toxicology 20 (2), 217-226, 2007 | 75 | 2007 |
| Structure and conformation of cyclopentene, cycloheptene and trans-cyclooctene MK Leong, VS Mastryukov, JE Boggs Journal of molecular structure 445 (1-3), 149-160, 1998 | 68 | 1998 |
| A method of combined quantum mechanical (QM)/molecular mechanics (MM) treatment of large polyatomic systems with charge transfer between the QM and MM fragments IB Bersuker, MK Leong, JE Boggs, RS Pearlman International journal of quantum chemistry 63 (6), 1051-1063, 1997 | 68 | 1997 |
| Hypoglycemic efficacy of docking selected natural compounds against α-glucosidase and α-amylase J Riyaphan, CH Jhong, SR Lin, CH Chang, MJ Tsai, DN Lee, PJ Sung, ... Molecules 23 (9), 2260, 2018 | 51 | 2018 |
| In silico prediction of PAMPA effective permeability using a two-QSAR approach CT Chi, MH Lee, CF Weng, MK Leong International journal of molecular sciences 20 (13), 3170, 2019 | 50 | 2019 |
| Structure and conformations of six-membered systems A6H12 (A= C, Si): ab initio study of cyclohexane and cyclohexasilane MK Leong, VS Mastryukov, JE Boggs The Journal of Physical Chemistry 98 (28), 6961-6966, 1994 | 46 | 1994 |
| Theoretical prediction of the complex P-glycoprotein substrate efflux based on the novel hierarchical support vector regression scheme C Chen, MH Lee, CF Weng, MK Leong Molecules 23 (7), 1820, 2018 | 38 | 2018 |
| Prodigiosin-emerged PI3K/Beclin-1-independent pathway elicits autophagic cell death in doxorubicin-sensitive and-resistant lung cancer WJ Chiu, SR Lin, YH Chen, MJ Tsai, MK Leong, CF Weng Journal of clinical medicine 7 (10), 321, 2018 | 35 | 2018 |
| Prediction of promiscuous p-glycoprotein inhibition using a novel machine learning scheme MK Leong, HB Chen, YH Shih PLoS One 7 (3), e33829, 2012 | 34 | 2012 |
| In silico prediction of the mutagenicity of nitroaromatic compounds using a novel two-QSAR approach YL Ding, YC Lyu, MK Leong Toxicology in Vitro 40, 102-114, 2017 | 32 | 2017 |
| Encapsulation of 16-hydroxycleroda-3, 13-dine-16, 15-olide in mesoporous silica nanoparticles as a natural dipeptidyl peptidase-4 inhibitor potentiated hypoglycemia in diabetic … PK Huang, SX Lin, MJ Tsai, MK Leong, SR Lin, RK Kankala, CH Lee, ... Nanomaterials 7 (5), 112, 2017 | 31 | 2017 |
| The perceptions of natural compounds against dipeptidyl peptidase 4 in diabetes: from in silico to in vivo SR Lin, CH Chang, MJ Tsai, H Cheng, JC Chen, MK Leong, CF Weng Therapeutic Advances in Chronic Disease 10, 2040622319875305, 2019 | 30 | 2019 |
| In silico Prediction of Skin Sensitization: Quo vadis? GH Ta, CF Weng, MK Leong Frontiers in Pharmacology 12, 655771, 2021 | 28 | 2021 |
| Development of a new predictive model for interactions with human cytochrome P450 2A6 using pharmacophore ensemble/support vector machine (PhE/SVM) approach MK Leong, YM Chen, HB Chen, PH Chen Pharmaceutical research 26, 987-1000, 2009 | 28 | 2009 |
| Mangosteen xanthone γ-mangostin exerts lowering blood glucose effect with potentiating insulin sensitivity through the mediation of AMPK/PPARγ SP Chen, SR Lin, TH Chen, HS Ng, HS Yim, MK Leong, CF Weng Biomedicine & Pharmacotherapy 144, 112333, 2021 | 26 | 2021 |
| Prediction of human cytochrome P450 2B6‐substrate interactions using hierarchical support vector regression approach MK Leong, YM Chen, TH Chen Journal of computational chemistry 30 (12), 1899-1909, 2009 | 26 | 2009 |
| Au (I)-benzimidazole/imidazole complexes. Liquid crystals and nanomaterials SJ Hsu, KM Hsu, MK Leong, IJB Lin Dalton Transactions, 1924-1931, 2008 | 25 | 2008 |
