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WONG Hoi Shan
WONG Hoi Shan
Nine Square Therapeutics
Adresse e-mail validée de ninesquaretx.com
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Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions
HS Wong, PA Dighe, V Mezera, PA Monternier, MD Brand
Journal of Biological Chemistry 292 (41), 16804-16809, 2017
4842017
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Nature metabolism 2, 1265–1283, 2020
3222020
Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts
HS Wong, B Benoit, MD Brand
Free Radical Biology and Medicine 130, 140-150, 2019
1192019
Are mitochondria the main contributor of reactive oxygen species in cells?
Y Zhang, HS Wong
Journal of Experimental Biology 224 (5), jeb221606, 2021
902021
Yang/Qi invigoration: an herbal therapy for chronic fatigue syndrome with yang deficiency?
PK Leong, HS Wong, J Chen, KM Ko
Evidence‐Based Complementary and Alternative Medicine 2015 (1), 945901, 2015
632015
The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production
RLS Goncalves, MA Watson, HS Wong, AL Orr, MD Brand
Redox biology 28, 101341, 2020
622020
β‐Sitosterol Enhances Cellular Glutathione Redox Cycling by Reactive Oxygen Species Generated From Mitochondrial Respiration: Protection Against Oxidant Injury in H9c2 Cells …
HS Wong, N Chen, PK Leong, KM Ko
Phytotherapy Research 28 (7), 999-1006, 2014
562014
Ursolic acid induces mitochondrial biogenesis through the activation of AMPK and PGC-1 in C2C12 myotubes: a possible mechanism underlying its beneficial effect on exercise …
J Chen, HS Wong, PK Leong, HY Leung, WM Chan, KM Ko
Food & function 8 (7), 2425-2436, 2017
542017
Herba Cistanches stimulates cellular glutathione redox cycling by reactive oxygen species generated from mitochondrial respiration in H9c2 cardiomyocytes
HS Wong, KM Ko
Pharmaceutical Biology 51 (1), 64-73, 2013
472013
Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site IQ of complex I in diverse cell lines
J Fang, HS Wong, MD Brand
Redox biology 37, 101722, 2020
452020
S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site IQ without inhibiting reverse electron flow through Complex I
HS Wong, PA Monternier, MD Brand
Free Radical Biology and Medicine 143, 545-559, 2019
392019
β-Sitosterol protects against carbon tetrachloride hepatotoxicity but not gentamicin nephrotoxicity in rats via the induction of mitochondrial glutathione redox cycling
HS Wong, JH Chen, PK Leong, HY Leung, WM Chan, KM Ko
Molecules 19 (11), 17649-17662, 2014
362014
Differential action between schisandrin A and schisandrin B in eliciting an anti-inflammatory action: the depletion of reduced glutathione and the induction of an antioxidant …
PK Leong, HS Wong, J Chen, WM Chan, HY Leung, KM Ko
PLoS One 11 (5), e0155879, 2016
322016
An ursolic acid-enriched extract of Cynomorium songaricum protects against carbon tetrachloride hepatotoxicity and gentamicin nephrotoxicity in rats possibly through a …
J Chen, HS Wong, HY Leung, PK Leong, WM Chan, N Chen, KM Ko
Journal of Functional Foods 7, 330-341, 2014
302014
Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes
MA Watson, HS Wong, MD Brand
Biochemical Society Transactions 47 (5), 1461-1469, 2019
292019
Ursolic Acid-enriched herba cynomorii extract induces mitochondrial uncoupling and glutathione redox cycling through mitochondrial reactive oxygen species generation …
J Chen, HS Wong, KM Ko
Molecules 19 (2), 1576-1591, 2014
232014
β-Sitosterol increases mitochondrial electron transport by fluidizing mitochondrial membranes and enhances mitochondrial responsiveness to increasing energy demand by the …
HS Wong, PK Leong, J Chen, HY Leung, WM Chan, KM Ko
Journal of functional foods 23, 253-260, 2016
192016
An ursolic acid-enriched Cynomorium songarium extract attenuates high fat diet-induced obesity in mice possibly through mitochondrial uncoupling
J Chen, HS Wong, HY Leung, PK Leong, WM Chan, KM Ko
Journal of functional foods 9, 211-224, 2014
172014
Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice
HS Wong, V Mezera, P Dighe, S Melov, AA Gerencser, RF Sweis, ...
Free Radical Biology and Medicine, 2021
162021
A traditional Chinese medicine approach in treating depression by promoting liver qi circulation: a western medicine perspective
RWL So, HS Wong, KM Ko
Chinese Medicine 6 (04), 187, 2015
152015
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