Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors F Soldner, D Hockemeyer, C Beard, Q Gao, GW Bell, EG Cook, G Hargus, ... Cell 136 (5), 964-977, 2009 | 2002 | 2009 |
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats G Hargus, O Cooper, M Deleidi, A Levy, K Lee, E Marlow, A Yow, ... Proceedings of the National Academy of Sciences 107 (36), 15921-15926, 2010 | 605 | 2010 |
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression P Reinhardt, B Schmid, LF Burbulla, DC Schöndorf, L Wagner, M Glatza, ... Cell stem cell 12 (3), 354-367, 2013 | 570 | 2013 |
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease O Cooper, H Seo, S Andrabi, C Guardia-Laguarta, J Graziotto, ... Science translational medicine 4 (141), 141ra90-141ra90, 2012 | 568 | 2012 |
COVID-19 neuropathology at columbia university irving medical center/New York presbyterian hospital KT Thakur, EH Miller, MD Glendinning, O Al-Dalahmah, MA Banu, ... Brain 144 (9), 2696-2708, 2021 | 375 | 2021 |
Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific … O Cooper, G Hargus, M Deleidi, A Blak, T Osborn, E Marlow, K Lee, ... Molecular and Cellular Neuroscience 45 (3), 258-266, 2010 | 276 | 2010 |
Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors M Ehrlich, S Mozafari, M Glatza, L Starost, S Velychko, AL Hallmann, ... Proceedings of the National Academy of Sciences 114 (11), E2243-E2252, 2017 | 254 | 2017 |
Differentiation plasticity of chondrocytes derived from mouse embryonic stem cells C Hegert, J Kramer, G Hargus, J Müller, K Guan, AM Wobus, PK Müller, ... Journal of cell science 115 (23), 4617-4628, 2002 | 175 | 2002 |
Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage O Al-Dalahmah, KT Thakur, AS Nordvig, ML Prust, W Roth, A Lignelli, ... Acta Neuropathologica Communications 8, 1-7, 2020 | 154 | 2020 |
Distinct neurodegenerative changes in an induced pluripotent stem cell model of frontotemporal dementia linked to mutant TAU protein M Ehrlich, AL Hallmann, P Reinhardt, MJ Araúzo-Bravo, S Korr, A Röpke, ... Stem cell reports 5 (1), 83-96, 2015 | 110 | 2015 |
Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein AL Hallmann, MJ Araúzo-Bravo, L Mavrommatis, M Ehrlich, A Röpke, ... Scientific reports 7 (1), 42991, 2017 | 102 | 2017 |
Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin I Dorn, K Klich, MJ Arauzo-Bravo, M Radstaak, S Santourlidis, F Ghanjati, ... haematologica 100 (1), 32, 2015 | 97 | 2015 |
Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum C Bernreuther, M Dihné, V Johann, J Schiefer, Y Cui, G Hargus, ... Journal of Neuroscience 26 (45), 11532-11539, 2006 | 95 | 2006 |
Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice YF Cui, JC Xu, G Hargus, I Jakovcevski, M Schachner, C Bernreuther PloS one 6 (3), e17126, 2011 | 76 | 2011 |
Human stem cell models of neurodegeneration: a novel approach to study mechanisms of disease development G Hargus, M Ehrlich, AL Hallmann, T Kuhlmann Acta neuropathologica 127, 151-173, 2014 | 72 | 2014 |
Close homologue of adhesion molecule L1 promotes survival of Purkinje and granule cells and granule cell migration during murine cerebellar development I Jakovcevski, J Siering, G Hargus, N Karl, L Hoelters, N Djogo, S Yin, ... Journal of Comparative Neurology 513 (5), 496-510, 2009 | 71 | 2009 |
Development of histocompatible primate‐induced pluripotent stem cells for neural transplantation M Deleidi, G Hargus, P Hallett, T Osborn, O Isacson Stem cells 29 (7), 1052-1063, 2011 | 69 | 2011 |
Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice YF Cui, G Hargus, JC Xu, JS Schmid, YQ Shen, M Glatzel, M Schachner, ... Brain 133 (1), 189-204, 2010 | 67 | 2010 |
Loss of Sox9 function results in defective chondrocyte differentiation of mouse embryonic stem cells in vitro G Hargus, R Kist, J Kramer, D Gerstel, A Neitz, G Scherer, J Rohwedel International Journal of Developmental Biology 52 (4), 323, 2008 | 57 | 2008 |
Oct4-induced reprogramming is required for adult brain neural stem cell differentiation into midbrain dopaminergic neurons M Deleidi, O Cooper, G Hargus, A Levy, O Isacson PloS one 6 (5), e19926, 2011 | 56 | 2011 |