| A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence CI Liu, GY Liu, Y Song, F Yin, ME Hensler, WY Jeng, V Nizet, AHJ Wang, ... Science 319 (5868), 1391-1394, 2008 | 598 | 2008 |
| Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy X Li, Y Song Journal of hematology & oncology 13, 1-14, 2020 | 354 | 2020 |
| Bisphosphonates target multiple sites in both cis-and trans-prenyltransferases RT Guo, R Cao, PH Liang, TP Ko, TH Chang, MP Hudock, WY Jeng, ... Proceedings of the National Academy of Sciences 104 (24), 10022-10027, 2007 | 230 | 2007 |
| An epigenomic approach to therapy for tamoxifen-resistant breast cancer Q Feng, Z Zhang, MJ Shea, CJ Creighton, C Coarfa, SG Hilsenbeck, ... Cell research 24 (7), 809-819, 2014 | 222 | 2014 |
| Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine Y Song, D Kesuma, J Wang, Y Deng, J Duan, JH Wang, RZ Qi Biochemical and biophysical research communications 317 (1), 128-132, 2004 | 222 | 2004 |
| Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation Y Zhang, R Cao, F Yin, MP Hudock, RT Guo, K Krysiak, S Mukherjee, ... Journal of the American Chemical Society 131 (14), 5153-5162, 2009 | 212 | 2009 |
| Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii SC Nair, CF Brooks, CD Goodman, A Strurm, GI McFadden, S Sundriyal, ... Journal of Experimental Medicine 208 (7), 1547-1559, 2011 | 189 | 2011 |
| Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies Y Yao, P Chen, J Diao, G Cheng, L Deng, JL Anglin, BVV Prasad, Y Song Journal of the American Chemical Society 133 (42), 16746-16749, 2011 | 186 | 2011 |
| Quantitative structure− activity relationships for γδ T cell activation by bisphosphonates JM Sanders, S Ghosh, JMW Chan, G Meints, H Wang, AM Raker, Y Song, ... Journal of medicinal chemistry 47 (2), 375-384, 2004 | 174 | 2004 |
| β-Carbolines as specific inhibitors of cyclin-Dependent kinases Y Song, J Wang, SF Teng, D Kesuma, Y Deng, J Duan, JH Wang, RZ Qi, ... Bioorganic & medicinal chemistry letters 12 (7), 1129-1132, 2002 | 170 | 2002 |
| Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives Y Song, F Wu, J Wu Journal of hematology & oncology 9, 1-21, 2016 | 162 | 2016 |
| DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia RE Rau, BA Rodriguez, M Luo, M Jeong, A Rosen, JH Rogers, ... Blood, The Journal of the American Society of Hematology 128 (7), 971-981, 2016 | 142 | 2016 |
| GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex B He, RB Lanz, W Fiskus, C Geng, P Yi, SM Hartig, K Rajapakshe, J Shou, ... Proceedings of the National Academy of Sciences 111 (51), 18261-18266, 2014 | 136 | 2014 |
| Discovery, X-ray crystallography and antiviral activity of allosteric inhibitors of flavivirus NS2B-NS3 protease Y Yao, T Huo, YL Lin, S Nie, F Wu, Y Hua, J Wu, AR Kneubehl, MB Vogt, ... Journal of the American Chemical Society 141 (17), 6832-6836, 2019 | 118 | 2019 |
| Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia Z Feng, Y Yao, C Zhou, F Chen, F Wu, L Wei, W Liu, S Dong, M Redell, ... Journal of hematology & oncology 9, 1-13, 2016 | 117 | 2016 |
| Inhibition of Staphyloxanthin Virulence Factor Biosynthesis in Staphylococcus aureus: In Vitro, in Vivo, and Crystallographic Results Y Song, CI Liu, FY Lin, JH No, M Hensler, YL Liu, WY Jeng, J Low, GY Liu, ... Journal of medicinal chemistry 52 (13), 3869-3880, 2009 | 114 | 2009 |
| NMR investigations of the static and dynamic structures of bisphosphonates on human bone: a molecular model S Mukherjee, Y Song, E Oldfield Journal of the American Chemical Society 130 (4), 1264-1273, 2008 | 113 | 2008 |
| Synthesis and structure–activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L JL Anglin, L Deng, Y Yao, G Cai, Z Liu, H Jiang, G Cheng, P Chen, ... Journal of medicinal chemistry 55 (18), 8066-8074, 2012 | 112 | 2012 |
| Crystallographic investigation and selective inhibition of mutant isocitrate dehydrogenase B Zheng, Y Yao, Z Liu, L Deng, JL Anglin, H Jiang, BVV Prasad, Y Song ACS medicinal chemistry letters 4 (6), 542-546, 2013 | 109 | 2013 |
| Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase− bisphosphonate complexes J Mao, S Mukherjee, Y Zhang, R Cao, JM Sanders, Y Song, Y Zhang, ... Journal of the American Chemical Society 128 (45), 14485-14497, 2006 | 109 | 2006 |