| Endoplasmic reticulum stress signalling–from basic mechanisms to clinical applications A Almanza, A Carlesso, C Chintha, S Creedican, D Doultsinos, B Leuzzi, ... The FEBS journal 286 (2), 241-278, 2019 | 880 | 2019 |
| Pharmacological targeting of IRE1 in cancer DP Raymundo, D Doultsinos, X Guillory, A Carlesso, LA Eriksson, ... Trends in cancer 6 (12), 1018-1030, 2020 | 95 | 2020 |
| Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors A Carlesso, C Chintha, AM Gorman, A Samali, LA Eriksson Scientific reports 9 (1), 3407, 2019 | 38 | 2019 |
| Peptidomimetic‐based identification of FDA‐approved compounds inhibiting IRE1 activity D Doultsinos, A Carlesso, C Chintha, JC Paton, AW Paton, A Samali, ... The FEBS Journal 288 (3), 945-960, 2021 | 28 | 2021 |
| Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1 C Chintha, A Carlesso, AM Gorman, A Samali, LA Eriksson RSC advances 10 (1), 367-375, 2020 | 28 | 2020 |
| Effect of kinase inhibiting rnase attenuator (Kira) compounds on the formation of face-to-face dimers of inositol-requiring enzyme 1: Insights from computational modeling A Carlesso, C Chintha, AM Gorman, A Samali, LA Eriksson International Journal of Molecular Sciences 20 (22), 5538, 2019 | 14 | 2019 |
| A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment D Pelizzari-Raymundo, D Doultsinos, R Pineau, C Sauzay, ... Iscience 26 (5), 2023 | 13 | 2023 |
| Binding analysis of the inositol-requiring enzyme 1 kinase domain A Carlesso, C Chintha, AM Gorman, A Samali, LA Eriksson Acs Omega 3 (10), 13313-13322, 2018 | 11 | 2018 |
| Sensor dimer disruption as a new mode of action to block the IRE1-mediated unfolded protein response KN Amarasinghe, D Pelizzari-Raymundo, A Carlesso, E Chevet, ... Computational and Structural Biotechnology Journal 20, 1584-1592, 2022 | 8 | 2022 |
| New insights on human IRE1 tetramer structures based on molecular modeling A Carlesso, J Hörberg, A Reymer, LA Eriksson Scientific Reports 10 (1), 17490, 2020 | 8 | 2020 |
| QM/MM well-tempered metadynamics study of the mechanism of XBP1 mRNA cleavage by inositol requiring enzyme 1α RNase SJ Mahdizadeh, E Palsson, A Carlesso, E Chevet, LA Eriksson Journal of Chemical Information and Modeling 62 (17), 4247-4260, 2022 | 7 | 2022 |
| Yeast as a tool for membrane protein production and structure determination A Carlesso, R Delgado, O Ruiz Isant, O Uwangue, D Valli, RM Bill, ... FEMS Yeast Research 22 (1), foac047, 2022 | 5 | 2022 |
| Deciphering the selectivity of inhibitor MKC9989 towards residue K907 in IRE1α; a multiscale in silico approach SJ Mahdizadeh, A Carlesso, LA Eriksson RSC advances 10 (33), 19720-19729, 2020 | 5 | 2020 |
| Selective inhibition of IRE1 signalling mediated by MKC9989: new insights from molecular docking and molecular dynamics simulations A Carlesso, LA Eriksson ChemistrySelect 4 (11), 3199-3203, 2019 | 5 | 2019 |
| Multiscale In Silico Study of the Mechanism of Activation of the RtcB Ligase by the PTP1B Phosphatase SJ Mahdizadeh, M Stier, A Carlesso, A Lamy, M Thomas, LA Eriksson Journal of Chemical Information and Modeling 64 (3), 905-917, 2024 | 3 | 2024 |
| Structural dynamics of therapeutic nucleic acids with phosphorothioate backbone modifications A Carlesso, J Hörberg, G Deganutti, A Reymer, P Matsson NAR Genomics and Bioinformatics 6 (2), lqae058, 2024 | 2 | 2024 |
| Different binding modalities of quercetin to inositol-requiring enzyme 1 of S. cerevisiae and human lead to opposite regulation SJ Mahdizadeh, J Grandén, D Pelizzari-Raymundo, X Guillory, ... Communications Chemistry 7 (1), 6, 2024 | 1 | 2024 |
| Mechanistic Insights into ASO-RNA Complexation: Advancing Antisense Oligonucleotide Design Strategies J Hörberg, A Carlesso, A Reymer bioRxiv, 2024.04. 18.590021, 2024 | | 2024 |
| A novel blood brain barrier-permeable IRE1 kinase inhibitor for adjuvant glioblastoma treatment in mice. D Pelizzari-Raymundo, D Doultsinos, R Pineau, C Sauzay, ... | | 2023 |
| Modeling and exploring human IRE1 as a strategy to design novel inhibitors: a computational approach A Carlesso | | 2019 |
