Jonathan H Chen

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Coauteurs

Susan M. KaechThe Salk Institute for Biological StudiesAdresse e-mail validée de salk.edu
Caleb LareauMemorial Sloan Kettering Cancer CenterAdresse e-mail validée de mskcc.org
Martin J. AryeeAssociate Professor, Dept of Data Science, Dana Farber Cancer Institute & Dept of Pathology, HarvardAdresse e-mail validée de ds.dfci.harvard.edu
Yang-Xin FuTsinghua UniversityAdresse e-mail validée de tsinghua.edu.cn
Weiguo CuiNorthwestern UniversityAdresse e-mail validée de northwestern.edu
vikram deshpandeProfessor of Pathology, Harvard Medical SchoolAdresse e-mail validée de bidmc.harvard.edu
Leif S. LudwigBerlin Institute of Health at Charité & Berlin Institute for Medical Systems Biology (MDC)Adresse e-mail validée de bih-charite.de
Genevieve M. BolandMassachusetts General HospitalAdresse e-mail validée de mgh.harvard.edu
Christoph MuusGraduate Student HarvardAdresse e-mail validée de seas.harvard.edu
Jacob C UlirschIllumina Artificial Intelligence LaboratoryAdresse e-mail validée de broadinstitute.org
Jason BuenrostroHarvard UniversityAdresse e-mail validée de harvard.edu
Nikhil S JoshiAssistant professor of Immunobiology, Yale UniversityAdresse e-mail validée de yale.edu
Guoliang CuiGerman cancer research center (DKFZ)Adresse e-mail validée de dkfz-heidelberg.de
Lieping ChenYale UniversityAdresse e-mail validée de yale.edu
Maryam Kherad PezhouhNorthwestern UniversityAdresse e-mail validée de northwestern.edu
Rafael A IrizarryProfessor, Biostatistics and Computational Biology, Dana-Farber and HarvardAdresse e-mail validée de ds.dfci.harvard.edu
Bradley BernsteinProfessor of Pathology, Harvard UniversityAdresse e-mail validée de broadinstitute.org
Daniel W RosenbergUCONN Health CenterAdresse e-mail validée de uchc.edu
Timothy HandAssociate ProfessorAdresse e-mail validée de chp.edu
Brian J LaidlawAssistant ProfessorAdresse e-mail validée de wustl.edu

Suivre

Jonathan H Chen

Northwestern University

Adresse e-mail validée de northwestern.edu

Cancer immunology T cell exhaustion multicellular networks microscopy pathology


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Defining T cell states associated with response to checkpoint immunotherapy in melanoma M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ... Cell 175 (4), 998-1013. e20, 2018	1643	2018
Resistance to checkpoint blockade therapy through inactivation of antigen presentation M Sade-Feldman, YJ Jiao, JH Chen, MS Rooney, M Barzily-Rokni, ... Nature communications 8 (1), 1-11, 2017	902	2017
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ... Nature 595 (7865), 107-113, 2021	706	2021
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics LS Ludwig, CA Lareau, JC Ulirsch, E Christian, C Muus, LH Li, K Pelka, ... Cell 176 (6), 1325-1339. e22, 2019	483	2019
Spatially organized multicellular immune hubs in human colorectal cancer K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ... Cell 184 (18), 4734-4752. e20, 2021	465	2021
The transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8+ T cells during chronic infection MM Staron, SM Gray, HD Marshall, IA Parish, JH Chen, CJ Perry, G Cui, ... Immunity 41 (5), 802-814, 2014	397	2014
Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease Y Sun, HM Chen, SK Subudhi, J Chen, R Koka, L Chen, YX Fu Nature medicine 8 (12), 1405-1413, 2002	245	2002
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection N Desai, A Neyaz, A Szabolcs, AR Shih, JH Chen, V Thapar, LT Nieman, ... Nature communications 11 (1), 1-15, 2020	241	2020
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ... Nature Genetics, 1-14, 2022	222	2022
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps B Chen, S Cherie’R, ET McKinley, AJ Simmons, MA Ramirez-Solano, ... Cell 184 (26), 6262-6280. e26, 2021	202	2021
Histopathologic features of colitis due to immunotherapy with anti-PD-1 antibodies JH Chen, MK Pezhouh, GY Lauwers, R Masia The American journal of surgical pathology 41 (5), 643-654, 2017	182	2017
Large-scale topological changes restrain malignant progression in colorectal cancer SE Johnstone, A Reyes, Y Qi, C Adriaens, E Hegazi, K Pelka, JH Chen, ... Cell 182 (6), 1474-1489. e23, 2020	176	2020
Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection JH Chen, CJ Perry, YC Tsui, MM Staron, IA Parish, CX Dominguez, ... Nature medicine 21 (4), 327-334, 2015	172	2015
Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells NS Joshi, W Cui, CX Dominguez, JH Chen, TW Hand, SM Kaech The Journal of Immunology 187 (8), 4068-4076, 2011	137	2011
Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1 IA Parish, HD Marshall, MM Staron, PA Lang, A Brüstle, JH Chen, W Cui, ... The Journal of clinical investigation 124 (8), 3455-3468, 2014	113	2014
Combined PD-1, BRAF and MEK inhibition in BRAF^V600E colorectal cancer: a phase 2 trial J Tian, JH Chen, SX Chao, K Pelka, M Giannakis, J Hess, K Burke, ... Nature Medicine, 1-9, 2023	106	2023
Immune‐related adverse events in the gastrointestinal tract: diagnostic utility of upper gastrointestinal biopsies ML Zhang, A Neyaz, D Patil, J Chen, M Dougan, V Deshpande Histopathology 76 (2), 233-243, 2020	89	2020
Targeting TBK1 to overcome resistance to cancer immunotherapy Y Sun, O Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, ... Nature, 1-3, 2023	87	2023
Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection ER Hinson, NS Joshi, JH Chen, C Rahner, YW Jung, X Wang, SM Kaech, ... The Journal of Immunology 184 (10), 5723-5731, 2010	71	2010
Immunotherapy with agonistic anti-CD137: two sides of a coin Y Sun, JH Chen, Y Fu Cell Mol Immunol 1 (1), 31-36, 2004	48	2004

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