Suivre
Chengzi I. Kaku
Chengzi I. Kaku
Adresse e-mail validée de scripps.edu
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Année
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
CG Rappazzo, LV Tse, CI Kaku, D Wrapp, M Sakharkar, D Huang, ...
Science 371 (6531), 823-829, 2021
3162021
Prolonged evolution of the human B cell response to SARS-CoV-2 infection
M Sakharkar, CG Rappazzo, WF Wieland-Alter, CL Hsieh, D Wrapp, ...
Science immunology 6 (56), eabg6916, 2021
1882021
Recall of preexisting cross-reactive B cell memory after Omicron BA. 1 breakthrough infection
CI Kaku, AJ Bergeron, C Ahlm, J Normark, M Sakharkar, MNE Forsell, ...
Science immunology 7 (73), eabq3511, 2022
1212022
Broad anti–SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination
CI Kaku, ER Champney, J Normark, M Garcia, CE Johnson, C Ahlm, ...
Science 375 (6584), 1041-1047, 2022
732022
A broad and potent neutralization epitope in SARS-related coronaviruses
M Yuan, X Zhu, W He, P Zhou, CI Kaku, T Capozzola, CY Zhu, X Yu, H Liu, ...
Proceedings of the National Academy of Sciences 119 (29), e2205784119, 2022
592022
Evolution of antibody immunity following Omicron BA. 1 breakthrough infection
CI Kaku, TN Starr, P Zhou, HL Dugan, P Khalifé, G Song, ER Champney, ...
Nature Communications 14 (1), 2751, 2023
562023
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers
P Schmidt, K Narayan, Y Li, CI Kaku, ME Brown, E Champney, ...
Science Translational Medicine 15 (688), eadg2783, 2023
292023
Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron
H Liu, CI Kaku, G Song, M Yuan, R Andrabi, DR Burton, LM Walker, ...
Communications Biology 5 (1), 766, 2022
142022
Prolonged evolution of the human B cell response to SARS-CoV-2 infection. Sci Immunol 6: eabg6916
M Sakharkar, CG Rappazzo, WF Wieland-Alter, CL Hsieh, D Wrapp, ...
142021
An engineered antibody with broad protective efficacy in murine models of SARS and COVID-19
CG Rappazzo, VT Longping, CI Kaku, D Wrapp, M Sakharkar, D Huang, ...
bioRxiv, 2020
142020
Revisiting an IgG Fc loss-of-function experiment: the role of complement in HIV broadly neutralizing antibody b12 activity
BS Goldberg, CI Kaku, J Dufloo, T Bruel, O Schwartz, DA Spencer, ...
Mbio 12 (5), 10.1128/mbio. 01743-21, 2021
82021
ADG20, a half-life–extended monoclonal antibody in development for the prevention and treatment of COVID-19, demonstrated broad in vitro neutralisation against SARS-CoV-2 variants
CI Kaku, P Schmidt, F Engler, Y Li, LM Walker
32nd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), 2022
62022
A recurring YYDRxG pattern in broadly neutralizing antibodies to a conserved site on SARS-CoV-2, variants of concern, and related viruses
H Liu, CI Kaku, G Song, M Yuan, R Andrabi, DR Burton, LM Walker, ...
biorxiv, 2021.12. 15.472864, 2021
62021
Evolution of antibody immunity following Omicron BA. 1 breakthrough infection. bioRxiv
CI Kaku, TN Starr, P Zhou, HL Dugan, P Khalifé, G Song, ER Champney, ...
52022
Evolution of antibody immunity following Omicron BA. 1 breakthrough infection (preprint)
CI Kaku, TN Starr, P Zhou, HL Dugan, P Khalife, G Song, ER Champney, ...
5*2022
Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19
EE Zumbrun, CI Kaku, L Dillinger, SE Zak, AI Kuehne, RR Bakken, ...
Antimicrobial Agents and Chemotherapy 67 (1), e01353-22, 2023
42023
Broad anti-SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 prime-boost vaccination
CI Kaku, ER Champney, J Normark, CE Johnson, C Ahlm, M Sakharkar, ...
medRxiv, 2021.12. 13.21267598, 2021
22021
Recall of pre-existing cross-reactive B cell memory following Omicron breakthrough infection (preprint)
CI Kaku, AJ Bergeron, C Ahlm, J Normark, M Sakharkar, MNE Forsell, ...
2022
Broad anti-SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 prime-boost vaccination (preprint)
C Kaku, E Champney, J Normark, C Johnson, C Ahlm, M Sakharkar, ...
2021
An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19 (preprint)
CG Rappazzo, VT Longping, CI Kaku, D Wrapp, M Sakharkar, D Huang, ...
2020
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