Ubiquitin-and ATP-dependent unfoldase activity of P97/VCP• NPLOC4• UFD1L is enhanced by a mutation that causes multisystem proteinopathy EE Blythe, KC Olson, V Chau, RJ Deshaies Proceedings of the National Academy of Sciences 114 (22), E4380-E4388, 2017 | 178 | 2017 |
Multisystem proteinopathy mutations in VCP/p97 increase NPLOC4· UFD1L binding and substrate processing EE Blythe, SN Gates, RJ Deshaies, A Martin Structure 27 (12), 1820-1829. e4, 2019 | 65 | 2019 |
Valosin-containing protein (VCP)–adaptor interactions are exceptionally dynamic and subject to differential modulation by a VCP inhibitor L Xue, EE Blythe, EC Freiberger, JL Mamrosh, AS Hebert, JM Reitsma, ... Molecular & Cellular Proteomics 15 (9), 2970-2986, 2016 | 56 | 2016 |
State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides SA Dai, Q Hu, R Gao, EE Blythe, KK Touhara, H Peacock, Z Zhang, ... Cell 185 (21), 3950-3965. e25, 2022 | 43 | 2022 |
Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2 ER Xu, EE Blythe, G Fischer, M Hyvönen Journal of Biological Chemistry 292 (30), 12516-12527, 2017 | 33 | 2017 |
An unusual pattern of ligand-receptor interactions for the α7 nicotinic acetylcholine receptor, with implications for the binding of varenicline EB Van Arnam, EE Blythe, HA Lester, DA Dougherty Molecular pharmacology 84 (2), 201-207, 2013 | 27 | 2013 |
β-Arrestin-independent endosomal cAMP signaling by a polypeptide hormone GPCR EE Blythe, M Von Zastrow Nature Chemical Biology 20 (3), 323-332, 2024 | 18 | 2024 |
Profiling the proximal proteome of the activated μ-opioid receptor BJ Polacco, BT Lobingier, EE Blythe, N Abreu, P Khare, MK Howard, ... Nature Chemical Biology, 1-11, 2024 | 10 | 2024 |
Profiling the diversity of agonist-selective effects on the proximal proteome environment of G protein-coupled receptors BJ Polacco, BT Lobingier, EE Blythe, N Abreu, J Xu, Q Li, ZZC Naing, ... BioRxiv, 2022 | 6 | 2022 |
Myosin VI drives arrestin-independent internalization and signaling of GPCRs NM Patel, L Ripoll, CJ Peach, N Ma, EE Blythe, N Vaidehi, NW Bunnett, ... Nature communications 15 (1), 1-15, 2024 | 1 | 2024 |
Profiling the proximal proteome of the mu opioid receptor identifies novel regulators of receptor signaling and trafficking BJ Polacco, BT Lobingier, EE Blythe, N Abreu, P Khare, MK Howard, ... bioRxiv, 2022.03. 28.486115, 2022 | 1 | 2022 |
Characterization of Adaptor Binding and Substrate Processing by Vcp/p97 EE Blythe California Institute of Technology, 2019 | | 2019 |
SUPPLEMENTAL FIGURE LEGENDS L Xue, EE Blythe, EC Freiberger, J Mamrosh, AS Hebert, JM Reitsma, ... | | |