| Digital twins in pharmaceutical and biopharmaceutical manufacturing: a literature review Y Chen, O Yang, C Sampat, P Bhalode, R Ramachandran, M Ierapetritou Processes 8 (9), 1088, 2020 | 205 | 2020 |
| A framework of hybrid model development with identification of plant‐model mismatch Y Chen, M Ierapetritou AIChE Journal 66 (10), e16996, 2020 | 67 | 2020 |
| Optimization of key energy and performance metrics for drug product manufacturing Y Chen, L Kotamarthy, A Dan, C Sampat, P Bhalode, R Singh, BJ Glasser, ... International Journal of Pharmaceutics 631, 122487, 2023 | 19 | 2023 |
| Enabling energy‐efficient manufacturing of pharmaceutical solid oral dosage forms via integrated techno‐economic analysis and advanced process modeling C Sampat, L Kotamarthy, P Bhalode, Y Chen, A Dan, S Parvani, ... Journal of Advanced Manufacturing and Processing 4 (4), e10136, 2022 | 18 | 2022 |
| Efficient Data-based Methodology for Model enhancement and Flowsheet analyses for Continuous Pharmaceutical Manufacturing P Bhalode, N Metta, Y Chen, M Ierapetritou Computer Aided Chemical Engineering 48, 127-132, 2020 | 13 | 2020 |
| Hybrid Modelling Strategies for Continuous Pharmaceutical Manufacturing within Digital Twin Framework P Bhalode, Y Chen, M Ierapetritou Computer Aided Chemical Engineering 49, 2125-2130, 2022 | 9 | 2022 |
| An integrated data management and informatics framework for continuous drug product manufacturing processes: A case study on two pilot plants Y Chen, C Sampat, YS Huang, S Ganesh, R Singh, R Ramachandran, ... International Journal of Pharmaceutics 642, 123086, 2023 | 8 | 2023 |
| Process Systems Engineering Tools toward Digital Twins of Pharmaceutical Continuous Manufacturing Processes Y Chen, M Ierapetritou, P Bhalode Continuous Pharmaceutical Processing and Process Analytical Technology, 449-475, 2023 | 3 | 2023 |
| PSE Tools and Challenges in the Development of Advanced Pharmaceutical Manufacturing Y Chen, P Bhalode, Y Ou, M Ierapetritou Computer Aided Chemical Engineering 49, 21-24, 2022 | 1 | 2022 |
| Adaptive Strategies for Updating Unit Operation Models and in-Line Monitoring of Blend Uniformity in Continuous Pharmaceutical Manufacturing Process Y Chen, S Gupta, A Roman-Ospino, F Muzzio, M Ierapetritou 2021 AIChE Annual Meeting, 2021 | | 2021 |
| Towards the Development of Digital Twin Framework for Continuous Pharmaceutical Manufacturing: Real-Time Model Maintenance and System Analyses P Bhalode, Y Chen, M Ierapetritou 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
| Development of Data-Driven and Hybrid Models for Continuous Pharmaceutical Manufacturing Lines Under Industry 4.0 Framework Y Chen, M Ierapetritou 2019 AIChE Annual Meeting, 2019 | | 2019 |
Marianthi IerapetritouGore Centennial Professor, Department of Chemical and Biomolecular Engineering, University ofAdresse e-mail validée de udel.edu
