Computational tools for copy number variation (CNV) detection using next-generation sequencing data: features and perspectives M Zhao, Q Wang, Q Wang, P Jia, Z Zhao BMC bioinformatics 14 (Suppl 11), S1, 2013 | 664 | 2013 |
Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder Z Zhao, J Xu, J Chen, S Kim, M Reimers, SA Bacanu, H Yu, C Liu, J Sun, ... Molecular psychiatry 20 (5), 563-572, 2015 | 167 | 2015 |
A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data Q Wang, R Chen, F Cheng, Q Wei, Y Ji, H Yang, X Zhong, R Tao, Z Wen, ... Nature neuroscience 22 (5), 691-699, 2019 | 140 | 2019 |
Quantitative network mapping of the human kinome interactome reveals new clues for rational kinase inhibitor discovery and individualized cancer therapy F Cheng, P Jia, Q Wang, Z Zhao Oncotarget 5 (11), 3697, 2014 | 116 | 2014 |
Studying tumorigenesis through network evolution and somatic mutational perturbations in the cancer interactome F Cheng, P Jia, Q Wang, CC Lin, WH Li, Z Zhao Molecular biology and evolution 31 (8), 2156-2169, 2014 | 83 | 2014 |
Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease J Fang, P Zhang, Q Wang, CW Chiang, Y Zhou, Y Hou, J Xu, R Chen, ... Alzheimer's Research & Therapy 14, 1-23, 2022 | 76 | 2022 |
Repurposing sertraline sensitizes non–small cell lung cancer cells to erlotinib by inducing autophagy X Jiang, W Lu, X Shen, Q Wang, J Lv, M Liu, F Cheng, Z Zhao, X Pang JCI insight 3 (11), 2018 | 71 | 2018 |
EW_dmGWAS: edge-weighted dense module search for genome-wide association studies and gene expression profiles Q Wang, H Yu, Z Zhao, P Jia Bioinformatics 31 (15), 2591-2594, 2015 | 67 | 2015 |
Searching for bidirectional promoters in Arabidopsis thaliana Q Wang, L Wan, D Li, L Zhu, M Qian, M Deng Bmc Bioinformatics 10, 1-10, 2009 | 67 | 2009 |
Anemia and red blood cell indices predict HIV-associated neurocognitive impairment in the highly active antiretroviral therapy era AR Kallianpur, Q Wang, P Jia, T Hulgan, Z Zhao, SL Letendre, RJ Ellis, ... The Journal of infectious diseases 213 (7), 1065-1073, 2016 | 60 | 2016 |
MSEA: detection and quantification of mutation hotspots through mutation set enrichment analysis P Jia, Q Wang, Q Chen, KE Hutchinson, W Pao, Z Zhao Genome biology 15, 1-16, 2014 | 54 | 2014 |
Systematic dissection of dysregulated transcription factor–mirna feed-forward loops across tumor types W Jiang, R Mitra, CC Lin, Q Wang, F Cheng, Z Zhao Briefings in bioinformatics 17 (6), 996-1008, 2016 | 53 | 2016 |
Multi-dimensional prioritization of dental caries candidate genes and its enriched dense network modules Q Wang, P Jia, KT Cuenco, E Feingold, ML Marazita, L Wang, Z Zhao PloS one 8 (10), e76666, 2013 | 42 | 2013 |
Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults SM Patton, Q Wang, T Hulgan, JR Connor, P Jia, Z Zhao, SL Letendre, ... Fluids and Barriers of the CNS 14, 1-16, 2017 | 28 | 2017 |
Association signals unveiled by a comprehensive gene set enrichment analysis of dental caries genome-wide association studies Q Wang, P Jia, KT Cuenco, Z Zeng, E Feingold, ML Marazita, L Wang, ... PLoS One 8 (8), e72653, 2013 | 24 | 2013 |
De novo pattern discovery enables robust assessment of functional consequences of non-coding variants H Yang, R Chen, Q Wang, Q Wei, Y Ji, G Zheng, X Zhong, NJ Cox, B Li Bioinformatics 35 (9), 1453-1460, 2019 | 23 | 2019 |
Heterogeneous DNA methylation contributes to tumorigenesis through inducing the loss of coexpression connectivity in colorectal cancer Q Wang, P Jia, F Cheng, Z Zhao Genes, Chromosomes and Cancer 54 (2), 110-121, 2015 | 16 | 2015 |
TMBserval: a statistical explainable learning model reveals weighted tumor mutation burden better categorizing therapeutic benefits Y Wang, J Wang, W Fang, X Xiao, Q Wang, J Zhao, J Liu, S Yang, Y Liu, ... Frontiers in Immunology 14, 1151755, 2023 | 14 | 2023 |
DRAMS: A tool to detect and re-align mixed-up samples for integrative studies of multi-omics data Y Jiang, G Giase, K Grennan, AW Shieh, Y Xia, L Han, Q Wang, Q Wei, ... PLoS computational biology 16 (4), e1007522, 2020 | 9 | 2020 |
Insight into the etiology of undifferentiated soft tissue sarcomas from a novel mouse model JT Fleming, E Brignola, L Chen, Y Guo, S Zhao, Q Wang, B Li, H Correa, ... Molecular Cancer Research 17 (5), 1024-1035, 2019 | 8 | 2019 |