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Kelsey Nolden (Kelsey Meacham)
Kelsey Nolden (Kelsey Meacham)
Adresse e-mail validée de mcw.edu
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Mitochondrial fission protein 1: emerging roles in organellar form and function in health and disease
UK Ihenacho, KA Meacham, MC Harwig, ME Widlansky, RB Hill
Frontiers in Endocrinology 12, 660095, 2021
962021
Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission
KA Nolden, MC Harwig, RB Hill
Journal of Biological Chemistry 299 (12), 2023
162023
Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission
JM Egner, KA Nolden, MC Harwig, RP Bonate, J De Anda, MH Tessmer, ...
Journal of Biological Chemistry 298 (12), 2022
162022
Altered zinc balance in the Atp7b−/− mouse reveals a mechanism of copper toxicity in Wilson disease
KA Meacham, MP Cortés, EM Wiggins, A Maass, M Latorre, M Ralle, ...
Metallomics 10 (11), 1595-1606, 2018
162018
Novel DNM1L variants impair mitochondrial dynamics through divergent mechanisms
KA Nolden, JM Egner, JJ Collier, OM Russell, CL Alston, MC Harwig, ...
Life Science Alliance 5 (12), 2022
122022
A novel Fis1 inhibiting peptide reverses diabetic endothelial dysfunction in human resistance arteries
KA Nolden, M Kakarla, JM Egner, J Wang, MC Harwig, VK Puppala, ...
Biorxiv, 2020.11. 16.385054, 2020
42020
Inhibition of Fis1 by Novel Peptide Pep213 or Molecular Suppression Reverses Diabetic-and High Glucose-Induced Endothelial Dysfunction in Human Resistance Arteries
M Kakarla, JM Egner, J Wang, MC Harwig, K Meacham, VK Puppala, ...
BioRxiv, 2020.11. 16.385054, 2020
22020
Mitochondrial Fission Protein 1 (Fis1) Regulates Endothelial Function in Resistance Arterioles in Health and Cardiometabolic Disease
J Wang, K Nolden, J Egner, M Kakarla, M Harwig, M Roberts, L Arnold, ...
Circulation 150 (Suppl_1), A4146321-A4146321, 2024
2024
Dynamins combine mechano-constriction and membrane remodeling to enable two-step mitochondrial fission via a ‘snap-through’instability
H Alimohamadi, EWC Luo, R Yang, S Gupta, KA Nolden, T Mandal, ...
bioRxiv, 2024
2024
Peptide Inhibitors of Human Mitochondrial Fission Protein 1 and Methods of Use
JM Egner, RB Hill, ME Widlansky, K Meacham
US Patent App. 18/252,073, 2024
2024
Structural studies of human FIS1 reveal a dynamic region important for DRP1 recruitment and mitochondrial fission
KA Meacham, JM Egner, MC Harwig, MH Tessmer, EL Noey, ...
Biophysical Journal 121 (3), 19a, 2022
2022
Altered Zinc Ion Levels and Transporter Expression Indicate That High Liver Copper Disrupts Zinc Metabolism in the Atp7b−/− Mouse Model of Wilson Disease
K Meacham, J Burkhead
The FASEB Journal 30, 850.3-850.3, 2016
2016
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