Mitochondrial fission protein 1: emerging roles in organellar form and function in health and disease UK Ihenacho, KA Meacham, MC Harwig, ME Widlansky, RB Hill Frontiers in Endocrinology 12, 660095, 2021 | 96 | 2021 |
Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission KA Nolden, MC Harwig, RB Hill Journal of Biological Chemistry 299 (12), 2023 | 16 | 2023 |
Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission JM Egner, KA Nolden, MC Harwig, RP Bonate, J De Anda, MH Tessmer, ... Journal of Biological Chemistry 298 (12), 2022 | 16 | 2022 |
Altered zinc balance in the Atp7b−/− mouse reveals a mechanism of copper toxicity in Wilson disease KA Meacham, MP Cortés, EM Wiggins, A Maass, M Latorre, M Ralle, ... Metallomics 10 (11), 1595-1606, 2018 | 16 | 2018 |
Novel DNM1L variants impair mitochondrial dynamics through divergent mechanisms KA Nolden, JM Egner, JJ Collier, OM Russell, CL Alston, MC Harwig, ... Life Science Alliance 5 (12), 2022 | 12 | 2022 |
A novel Fis1 inhibiting peptide reverses diabetic endothelial dysfunction in human resistance arteries KA Nolden, M Kakarla, JM Egner, J Wang, MC Harwig, VK Puppala, ... Biorxiv, 2020.11. 16.385054, 2020 | 4 | 2020 |
Inhibition of Fis1 by Novel Peptide Pep213 or Molecular Suppression Reverses Diabetic-and High Glucose-Induced Endothelial Dysfunction in Human Resistance Arteries M Kakarla, JM Egner, J Wang, MC Harwig, K Meacham, VK Puppala, ... BioRxiv, 2020.11. 16.385054, 2020 | 2 | 2020 |
Mitochondrial Fission Protein 1 (Fis1) Regulates Endothelial Function in Resistance Arterioles in Health and Cardiometabolic Disease J Wang, K Nolden, J Egner, M Kakarla, M Harwig, M Roberts, L Arnold, ... Circulation 150 (Suppl_1), A4146321-A4146321, 2024 | | 2024 |
Dynamins combine mechano-constriction and membrane remodeling to enable two-step mitochondrial fission via a ‘snap-through’instability H Alimohamadi, EWC Luo, R Yang, S Gupta, KA Nolden, T Mandal, ... bioRxiv, 2024 | | 2024 |
Peptide Inhibitors of Human Mitochondrial Fission Protein 1 and Methods of Use JM Egner, RB Hill, ME Widlansky, K Meacham US Patent App. 18/252,073, 2024 | | 2024 |
Structural studies of human FIS1 reveal a dynamic region important for DRP1 recruitment and mitochondrial fission KA Meacham, JM Egner, MC Harwig, MH Tessmer, EL Noey, ... Biophysical Journal 121 (3), 19a, 2022 | | 2022 |
Altered Zinc Ion Levels and Transporter Expression Indicate That High Liver Copper Disrupts Zinc Metabolism in the Atp7b−/− Mouse Model of Wilson Disease K Meacham, J Burkhead The FASEB Journal 30, 850.3-850.3, 2016 | | 2016 |