Suivre
Somayah S. Elsayed
Somayah S. Elsayed
Leiden University, the Netherlands
Adresse e-mail validée de biology.leidenuniv.nl
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Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome
VJ Carrión, J Perez-Jaramillo, V Cordovez, V Tracanna, M De Hollander, ...
Science 366 (6465), 606-612, 2019
8462019
Artificial intelligence for natural product drug discovery
MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ...
Nature Reviews Drug Discovery 22 (11), 895-916, 2023
1422023
Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert
SS Elsayed, F Trusch, H Deng, A Raab, I Prokes, K Busarakam, ...
The Journal of organic chemistry 80 (20), 10252-10260, 2015
1192015
Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides
AM Kloosterman, P Cimermancic, SS Elsayed, C Du, M Hadjithomas, ...
PLoS biology 18 (12), e3001026, 2020
1092020
Discovery of a single monooxygenase that catalyzes carbamate formation and ring contraction in the biosynthesis of the legonmycins
S Huang, J Tabudravu, SS Elsayed, J Travert, D Peace, MH Tong, ...
Angewandte Chemie International Edition 54 (43), 12697-12701, 2015
622015
3-Keto-22-epi-28-nor-cathasterone, a brassinosteroid-related metabolite from Cystoseira myrica
AHA Hamdy, EA Aboutabl, S Sameer, AA Hussein, AR Díaz-Marrero, ...
Steroids 74 (12), 927-930, 2009
432009
Biosynthesis of neocarazostatin A reveals the sequential carbazole prenylation and hydroxylation in the tailoring steps
S Huang, SS Elsayed, M Lv, J Tabudravu, ME Rateb, R Gyampoh, ...
Chemistry & Biology 22 (12), 1633-1642, 2015
402015
Discovery of novel glycerolated quinazolinones from Streptomyces sp. MBT27
NV Machushynets, C Wu, SS Elsayed, T Hankemeier, GP van Wezel
Journal of Industrial Microbiology and Biotechnology 46 (3-4), 483-492, 2019
302019
Discovery of actinomycin L, a new member of the actinomycin family of antibiotics
NV Machushynets, SS Elsayed, C Du, MA Siegler, M de la Cruz, ...
Scientific Reports 12 (1), 2813, 2022
202022
The ubiquitous catechol moiety elicits siderophore and angucycline production in Streptomyces
DA van Bergeijk, SS Elsayed, C Du, IN Santiago, AM Roseboom, L Zhang, ...
Communications Chemistry 5 (1), 14, 2022
202022
Atypical Spirotetronate Polyketides Identified in the Underexplored Genus Streptacidiphilus
SS Elsayed, G Genta-Jouve, VJ Carrión, PH Nibbering, MA Siegler, ...
The Journal of Organic Chemistry 85 (16), 10648-10657, 2020
162020
The plant stress hormone jasmonic acid evokes defensive responses in streptomycetes
A Van der Meij, SS Elsayed, C Du, J Willemse, TM Wood, NI Martin, ...
Applied and Environmental Microbiology 89 (11), e01239-23, 2023
92023
Functional and structural insights into a novel promiscuous ketoreductase of the lugdunomycin biosynthetic pathway
X Xiao, SS Elsayed, C Wu, HU van der Heul, M Metsä-Ketelä, C Du, ...
ACS chemical biology 15 (9), 2529-2538, 2020
92020
Total synthesis and structure assignment of the relacidine lipopeptide antibiotics and preparation of analogues with enhanced stability
K Al Ayed, D Zamarbide Losada, NV Machushynets, B Terlouw, ...
ACS infectious diseases 9 (4), 739-748, 2023
72023
Dynamic effects of probiotic formula ecologic® 825 on human small intestinal ileostoma microbiota: a network theory approach
J Jansma, NU Thome, M Schwalbe, AC Chatziioannou, SS Elsayed, ...
Gut Microbes 15 (1), 2232506, 2023
42023
Unravelling key enzymatic steps in C-ring cleavage during angucycline biosynthesis
SS Elsayed, HU van der Heul, X Xiao, A Nuutila, LR Baars, C Wu, ...
Communications Chemistry 6 (1), 281, 2023
42023
Taxonomic and metabolic diversity of Actinobacteria isolated from faeces of a 28,000-year-old mammoth
DA van Bergeijk, HE Augustijn, SS Elsayed, J Willemse, VJ Carrión, ...
bioRxiv, 2022.12. 22.521380, 2022
42022
nanoRAPIDS as an analytical pipeline for the discovery of novel bioactive metabolites in complex culture extracts at the nanoscale
I Nuñez Santiago, NV Machushynets, M Mladic, DA van Bergeijk, ...
Communications Chemistry 7 (1), 71, 2024
32024
Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products
AM Kloosterman, P Cimermancic, SS Elsayed, C Du, M Hadjithomas, ...
bioRxiv, 2020.05. 19.104752, 2020
32020
Discovery and Derivatization of Tridecaptin Antibiotics with Altered Host Specificity and Enhanced Bioactivity
NV Machushynets, K Al Ayed, BR Terlouw, C Du, NP Buijs, J Willemse, ...
ACS Chemical Biology 19 (5), 1106-1115, 2024
22024
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