Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome VJ Carrión, J Perez-Jaramillo, V Cordovez, V Tracanna, M De Hollander, ... Science 366 (6465), 606-612, 2019 | 846 | 2019 |
Artificial intelligence for natural product drug discovery MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ... Nature Reviews Drug Discovery 22 (11), 895-916, 2023 | 142 | 2023 |
Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert SS Elsayed, F Trusch, H Deng, A Raab, I Prokes, K Busarakam, ... The Journal of organic chemistry 80 (20), 10252-10260, 2015 | 119 | 2015 |
Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides AM Kloosterman, P Cimermancic, SS Elsayed, C Du, M Hadjithomas, ... PLoS biology 18 (12), e3001026, 2020 | 109 | 2020 |
Discovery of a single monooxygenase that catalyzes carbamate formation and ring contraction in the biosynthesis of the legonmycins S Huang, J Tabudravu, SS Elsayed, J Travert, D Peace, MH Tong, ... Angewandte Chemie International Edition 54 (43), 12697-12701, 2015 | 62 | 2015 |
3-Keto-22-epi-28-nor-cathasterone, a brassinosteroid-related metabolite from Cystoseira myrica AHA Hamdy, EA Aboutabl, S Sameer, AA Hussein, AR Díaz-Marrero, ... Steroids 74 (12), 927-930, 2009 | 43 | 2009 |
Biosynthesis of neocarazostatin A reveals the sequential carbazole prenylation and hydroxylation in the tailoring steps S Huang, SS Elsayed, M Lv, J Tabudravu, ME Rateb, R Gyampoh, ... Chemistry & Biology 22 (12), 1633-1642, 2015 | 40 | 2015 |
Discovery of novel glycerolated quinazolinones from Streptomyces sp. MBT27 NV Machushynets, C Wu, SS Elsayed, T Hankemeier, GP van Wezel Journal of Industrial Microbiology and Biotechnology 46 (3-4), 483-492, 2019 | 30 | 2019 |
Discovery of actinomycin L, a new member of the actinomycin family of antibiotics NV Machushynets, SS Elsayed, C Du, MA Siegler, M de la Cruz, ... Scientific Reports 12 (1), 2813, 2022 | 20 | 2022 |
The ubiquitous catechol moiety elicits siderophore and angucycline production in Streptomyces DA van Bergeijk, SS Elsayed, C Du, IN Santiago, AM Roseboom, L Zhang, ... Communications Chemistry 5 (1), 14, 2022 | 20 | 2022 |
Atypical Spirotetronate Polyketides Identified in the Underexplored Genus Streptacidiphilus SS Elsayed, G Genta-Jouve, VJ Carrión, PH Nibbering, MA Siegler, ... The Journal of Organic Chemistry 85 (16), 10648-10657, 2020 | 16 | 2020 |
The plant stress hormone jasmonic acid evokes defensive responses in streptomycetes A Van der Meij, SS Elsayed, C Du, J Willemse, TM Wood, NI Martin, ... Applied and Environmental Microbiology 89 (11), e01239-23, 2023 | 9 | 2023 |
Functional and structural insights into a novel promiscuous ketoreductase of the lugdunomycin biosynthetic pathway X Xiao, SS Elsayed, C Wu, HU van der Heul, M Metsä-Ketelä, C Du, ... ACS chemical biology 15 (9), 2529-2538, 2020 | 9 | 2020 |
Total synthesis and structure assignment of the relacidine lipopeptide antibiotics and preparation of analogues with enhanced stability K Al Ayed, D Zamarbide Losada, NV Machushynets, B Terlouw, ... ACS infectious diseases 9 (4), 739-748, 2023 | 7 | 2023 |
Dynamic effects of probiotic formula ecologic® 825 on human small intestinal ileostoma microbiota: a network theory approach J Jansma, NU Thome, M Schwalbe, AC Chatziioannou, SS Elsayed, ... Gut Microbes 15 (1), 2232506, 2023 | 4 | 2023 |
Unravelling key enzymatic steps in C-ring cleavage during angucycline biosynthesis SS Elsayed, HU van der Heul, X Xiao, A Nuutila, LR Baars, C Wu, ... Communications Chemistry 6 (1), 281, 2023 | 4 | 2023 |
Taxonomic and metabolic diversity of Actinobacteria isolated from faeces of a 28,000-year-old mammoth DA van Bergeijk, HE Augustijn, SS Elsayed, J Willemse, VJ Carrión, ... bioRxiv, 2022.12. 22.521380, 2022 | 4 | 2022 |
nanoRAPIDS as an analytical pipeline for the discovery of novel bioactive metabolites in complex culture extracts at the nanoscale I Nuñez Santiago, NV Machushynets, M Mladic, DA van Bergeijk, ... Communications Chemistry 7 (1), 71, 2024 | 3 | 2024 |
Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products AM Kloosterman, P Cimermancic, SS Elsayed, C Du, M Hadjithomas, ... bioRxiv, 2020.05. 19.104752, 2020 | 3 | 2020 |
Discovery and Derivatization of Tridecaptin Antibiotics with Altered Host Specificity and Enhanced Bioactivity NV Machushynets, K Al Ayed, BR Terlouw, C Du, NP Buijs, J Willemse, ... ACS Chemical Biology 19 (5), 1106-1115, 2024 | 2 | 2024 |