Suivre
Simon Melov
Simon Melov
Professor
Adresse e-mail validée de buckinstitute.org
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Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
Y Li, TT Huang, EJ Carlson, S Melov, PC Ursell, JL Olson, LJ Noble, ...
Nature genetics 11 (4), 376-381, 1995
22631995
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
S Parrinello, E Samper, A Krtolica, J Goldstein, S Melov, J Campisi
Nature cell biology 5 (8), 741-747, 2003
13722003
Cellular senescence promotes adverse effects of chemotherapy and cancer relapse
M Demaria, MN O'Leary, J Chang, L Shao, SU Liu, F Alimirah, K Koenig, ...
Cancer discovery 7 (2), 165-176, 2017
12682017
Extension of life-span with superoxide dismutase/catalase mimetics
S Melov, J Ravenscroft, S Malik, MS Gill, DW Walker, PE Clayton, ...
Science 289 (5484), 1567-1569, 2000
12182000
From discoveries in ageing research to therapeutics for healthy ageing
J Campisi, P Kapahi, GJ Lithgow, S Melov, JC Newman, E Verdin
Nature 571 (7764), 183-192, 2019
11642019
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress.
GJ Lithgow, TM White, S Melov, TE Johnson
Proceedings of the National Academy of Sciences 92 (16), 7540-7544, 1995
10711995
Unmasking transcriptional heterogeneity in senescent cells
A Hernandez-Segura, TV de Jong, S Melov, V Guryev, J Campisi, ...
Current Biology 27 (17), 2652-2660. e4, 2017
8252017
Mitochondrial disease in mouse results in increased oxidative stress
LA Esposito, S Melov, A Panov, BA Cottrell, DC Wallace
Proceedings of the National Academy of Sciences 96 (9), 4820-4825, 1999
7931999
Mitochondrial disease in superoxide dismutase 2 mutant mice
S Melov, P Coskun, M Patel, R Tuinstra, B Cottrell, AS Jun, TH Zastawny, ...
Proceedings of the National Academy of Sciences 96 (3), 846-851, 1999
7331999
A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
S Melov, JA Schneider, BJ Day, D Hinerfeld, P Coskun, SS Mirra, ...
Nature genetics 18 (2), 159-163, 1998
6621998
Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise
DJ Mahoney, G Parise, S Melov, A Safdar, MA Tarnopolsky
The FASEB journal 19 (11), 1498-1500, 2005
5302005
Cellular senescence: a link between cancer and age-related degenerative disease?
J Campisi, JK Andersen, P Kapahi, S Melov
Seminars in cancer biology 21 (6), 354-359, 2011
5242011
Oxidative stress and aging: beyond correlation
TR Golden, DA Hinerfeld, S Melov
Aging cell 1 (2), 117-123, 2002
5022002
Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice
A Safdar, JM Bourgeois, DI Ogborn, JP Little, BP Hettinga, M Akhtar, ...
Proceedings of the National Academy of Sciences 108 (10), 4135-4140, 2011
4972011
Resistance exercise reverses aging in human skeletal muscle
S Melov, MA Tarnopolsky, K Beckman, K Felkey, A Hubbard
PloS one 2 (5), e465, 2007
4842007
Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage
JD Crane, DI Ogborn, C Cupido, S Melov, A Hubbard, JM Bourgeois, ...
Science translational medicine 4 (119), 119ra13-119ra13, 2012
4642012
Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells
MC An, N Zhang, G Scott, D Montoro, T Wittkop, S Mooney, S Melov, ...
Cell stem cell 11 (2), 253-263, 2012
4522012
Mitochondrial oxidative stress causes hyperphosphorylation of tau
S Melov, PA Adlard, K Morten, F Johnson, TR Golden, D Hinerfeld, ...
PloS one 2 (6), e536, 2007
4392007
SOD2 in mitochondrial dysfunction and neurodegeneration
JM Flynn, S Melov
Free Radical Biology and Medicine 62, 4-12, 2013
4042013
Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle
S Melov, JM Shoffner, A Kaufman, DC Wallace
Nucleic acids research 23 (20), 4122-4126, 1995
3591995
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