| Structural insights into the Niemann-Pick C1 (NPC1)-mediated cholesterol transfer and Ebola infection X Gong, H Qian, X Zhou, J Wu, T Wan, P Cao, W Huang, X Zhao, X Wang, ... Cell 165 (6), 1467-1478, 2016 | 340 | 2016 |
| Structure of the human lipid exporter ABCA1 H Qian, X Zhao, P Cao, J Lei, N Yan, X Gong Cell 169 (7), 1228-1239. e10, 2017 | 284 | 2017 |
| Structural and functional diversity calls for a new classification of ABC transporters C Thomas, SG Aller, K Beis, EP Carpenter, G Chang, L Chen, E Dassa, ... FEBS letters 594 (23), 3767-3775, 2020 | 239 | 2020 |
| Structural basis for the recognition of Sonic Hedgehog by human Patched1 X Gong, H Qian, P Cao, X Zhao, Q Zhou, J Lei, N Yan Science 361 (6402), eaas8935, 2018 | 221 | 2018 |
| Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm H Qian, P Cao, M Hu, S Gao, N Yan, X Gong Nature communications 10 (1), 2320, 2019 | 89 | 2019 |
| Structural insights into the assembly and substrate selectivity of human SPT–ORMDL3 complex S Li, T Xie, P Liu, L Wang, X Gong Nature Structural & Molecular Biology 28 (3), 249-257, 2021 | 74 | 2021 |
| A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols R Yan, P Cao, W Song, H Qian, X Du, HW Coates, X Zhao, Y Li, S Gao, ... Science 371 (6533), eabb2224, 2021 | 70 | 2021 |
| Structural basis of substrate recognition and translocation by human ABCA4 T Xie, Z Zhang, Q Fang, B Du, X Gong Nature Communications 12 (1), 3853, 2021 | 54 | 2021 |
| Structural insights into the photoactivation of Arabidopsis CRY2 L Ma, Z Guan, Q Wang, X Yan, J Wang, Z Wang, J Cao, D Zhang, X Gong, ... Nature Plants 6 (12), 1432-1438, 2020 | 46 | 2020 |
| Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels R Ren, X Zhou, Y He, M Ke, J Wu, X Liu, C Yan, Y Wu, X Gong, X Lei, ... Science 349 (6244), 187-191, 2015 | 37 | 2015 |
| Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization X Gong, H Qian, W Shao, J Li, J Wu, JJ Liu, W Li, HW Wang, ... Cell Research 26 (11), 1197-1211, 2016 | 27 | 2016 |
| Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis T Xie, P Liu, X Wu, F Dong, Z Zhang, J Yue, U Mahawar, F Farooq, ... Nature Communications 14 (1), 3475, 2023 | 26 | 2023 |
| AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway HY Mak, Q Ouyang, S Tumanov, J Xu, P Rong, F Dong, SM Lam, X Wang, ... Nature Communications 12 (1), 6877, 2021 | 26 | 2021 |
| Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition X Gong, J Li, W Shao, J Wu, H Qian, R Ren, P Espenshade, N Yan Cell Research 25 (4), 401-411, 2015 | 26 | 2015 |
| Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex P Liu, T Xie, X Wu, G Han, SD Gupta, Z Zhang, J Yue, F Dong, K Gable, ... Science Advances 9 (13), eadg0728, 2023 | 21 | 2023 |
| Cryo-EM structures of the human surfactant lipid transporter ABCA3 T Xie, Z Zhang, J Yue, Q Fang, X Gong Science Advances 8 (14), eabn3727, 2022 | 20 | 2022 |
| Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release W Li, L Wang, BM Wierbowski, M Lu, F Dong, W Liu, S Li, P Wang, A Salic, ... Nature Communications 12 (1), 6966, 2021 | 13 | 2021 |
| Structure and mechanism of a eukaryotic ceramide synthase complex T Xie, Q Fang, Z Zhang, Y Wang, F Dong, X Gong The EMBO Journal 42 (24), e114889, 2023 | 8 | 2023 |
| Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide T Xie, F Dong, G Han, X Wu, P Liu, Z Zhang, J Zhong, S Niranjanakumari, ... Cell Reports 43 (2), 2024 | 5 | 2024 |
| Mechanism of ceramide synthase inhibition by fumonisin B1 Z Zhang, Q Fang, T Xie, X Gong Structure 32 (9), 1419-1428. e4, 2024 | 4 | 2024 |
Nieng YanShenzhen Medical Academy of Research & Translation (SMART) / Tsinghua University / PrincetonAdresse e-mail validée de smart.org.cn