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Chantal Van Opbergen
Chantal Van Opbergen
New York University School of Medicine
Adresse e-mail validée de nyulangone.org
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Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm
M Cerrone, J Montnach, X Lin, YT Zhao, M Zhang, E Agullo-Pascual, ...
Nature communications 8 (1), 106, 2017
2182017
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy
JD Roberts, NP Murphy, RM Hamilton, ER Lubbers, CA James, CF Kline, ...
The Journal of Clinical Investigation 129 (8), 3171-3184, 2019
582019
Gelatin microspheres as vehicle for cardiac progenitor cells delivery to the myocardium
DAM Feyen, R Gaetani, J Deddens, D van Keulen, C van Opbergen, ...
Advanced healthcare materials 5 (9), 1071-1079, 2016
542016
Potential new mechanisms of pro-arrhythmia in arrhythmogenic cardiomyopathy: focus on calcium sensitive pathways
CJM Van Opbergen, M Delmar, TAB Van Veen
Netherlands Heart Journal 25, 157-169, 2017
522017
Optogenetic sensors in the zebrafish heart: a novel in vivo electrophysiological tool to study cardiac arrhythmogenesis
CJM van Opbergen, CD Koopman, BJM Kok, T Knöpfel, SL Renninger, ...
Theranostics 8 (17), 4750, 2018
502018
Plakophilin-2 haploinsufficiency causes calcium handling deficits and modulates the cardiac response towards stress
CJM van Opbergen, M Noorman, A Pfenniger, JS Copier, SH Vermij, Z Li, ...
International journal of molecular sciences 20 (17), 4076, 2019
432019
Mitochondrial dysfunction as substrate for arrhythmogenic cardiomyopathy: a search for new disease mechanisms
CJM Van Opbergen, L Den Braven, M Delmar, TAB Van Veen
Frontiers in physiology 10, 1496, 2019
412019
Cardiac Ca2+ signalling in zebrafish: Translation of findings to man
CJM van Opbergen, SM van der Voorn, MA Vos, TP de Boer, ...
Progress in biophysics and molecular biology 138, 45-58, 2018
382018
Role of plakophilin-2 expression on exercise-related progression of arrhythmogenic right ventricular cardiomyopathy: a translational study
M Cerrone, GM Marron-Linares, CJM Van Opbergen, S Costa, M Bourfiss, ...
European heart journal 43 (12), 1251-1264, 2022
352022
Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2–Deficient Hearts
CJM Van Opbergen, N Bagwan, SR Maurya, JC Kim, AN Smith, ...
Circulation 145 (19), 1480-1496, 2022
342022
Loss of nuclear envelope integrity and increased oxidant production cause DNA damage in adult hearts deficient in PKP2: a molecular substrate of ARVC
M Pérez-Hernández, CJM van Opbergen, N Bagwan, CR Vissing, ...
Circulation 146 (11), 851-867, 2022
312022
The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes
MS Nielsen, CJM van Opbergen, TAB van Veen, M Delmar
Physiological Reviews 103 (3), 2271-2319, 2023
262023
Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model of phospholamban R14del cardiomyopathy
SM Kamel, CJM van Opbergen, CD Koopman, AO Verkerk, BJD Boukens, ...
Nature communications 12 (1), 7151, 2021
242021
Transcriptomic coupling of PKP2 with inflammatory and immune pathways endogenous to adult cardiac myocytes
M Pérez-Hernández, GM Marrón-Liñares, F Schlamp, A Heguy, ...
Frontiers in physiology 11, 623190, 2021
222021
AAV-mediated delivery of Plakophilin-2a arrests progression of arrhythmogenic right ventricular cardiomyopathy in murine hearts: preclinical evidence supporting gene therapy in …
CJM van Opbergen, B Narayanan, CB Sacramento, KM Stiles, V Mishra, ...
Circulation: Genomic and Precision Medicine 17 (1), e004305, 2024
192024
Blockade of the adenosine 2A receptor mitigates the cardiomyopathy induced by loss of plakophilin-2 expression
M Cerrone, CJM Van Opbergen, K Malkani, N Irrera, M Zhang, ...
Frontiers in Physiology 9, 1750, 2018
132018
In silico Identification of Disrupted Myocardial Calcium Homeostasis as Proarrhythmic Trigger in Arrhythmogenic Cardiomyopathy
A Lyon, CJM Van Opbergen, M Delmar, J Heijman, TAB Van Veen
Frontiers in physiology 12, 732573, 2021
62021
“Orphan” connexin43 in plakophilin-2 deficient hearts revealed by volume electron microscopy
CJM van Opbergen, J Sall, C Petzold, K Dancel-Manning, M Delmar, ...
Frontiers in Cell and Developmental Biology 10, 843687, 2022
52022
Nanogold based protein localization enables subcellular visualization of cell junction protein by SBF-SEM
FX Liang, J Sall, C Petzold, CJM van Opbergen, X Liang, M Delmar
Methods in cell biology 177, 55-81, 2023
22023
Leaky RyR2 channels as pro-arrhythmic trigger in the PKP2-deficient atrial myocardium
CJM Van Opbergen, K Phadke, X Lin, M Zhang, A Lundby, M Cerrone, ...
Cardiovascular Research 120 (Supplement_1), cvae088. 099, 2024
2024
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