Osteosarcoma: cells‐of‐origin, cancer stem cells, and targeted therapies A Abarrategi, J Tornin, L Martinez-Cruzado, A Hamilton, ... Stem cells international 2016 (1), 3631764, 2016 | 234 | 2016 |
Bone microenvironment signals in osteosarcoma development A Alfranca, L Martinez-Cruzado, J Tornin, A Abarrategi, T Amaral, ... Cellular and Molecular Life Sciences 72, 3097-3113, 2015 | 215 | 2015 |
Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells R Rubio, A Abarrategi, J Garcia‐Castro, L Martinez‐Cruzado, C Suarez, ... Stem cells 32 (5), 1136-1148, 2014 | 109 | 2014 |
Expression of FUS-CHOP fusion protein in immortalized/transformed human mesenchymal stem cells drives mixoid liposarcoma formation R Rodriguez, J Tornin, C Suarez, A Astudillo, R Rubio, C Yauk, A Williams, ... Stem cells 31 (10), 2061-2072, 2013 | 84 | 2013 |
Pyruvate plays a main role in the antitumoral selectivity of cold atmospheric plasma in osteosarcoma J Tornin, M Mateu-Sanz, A Rodríguez, C Labay, R Rodríguez, C Canal Scientific reports 9 (1), 10681, 2019 | 83 | 2019 |
Evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures J Tornin, C Labay, F Tampieri, MP Ginebra, C Canal Nature Protocols 16 (6), 2826-2850, 2021 | 81 | 2021 |
Cold plasma-treated ringer’s saline: A weapon to target osteosarcoma M Mateu-Sanz, J Tornín, B Brulin, A Khlyustova, MP Ginebra, P Layrolle, ... Cancers 12 (1), 227, 2020 | 73 | 2020 |
Aldh1 expression and activity increase during tumor evolution in sarcoma cancer stem cell populations L Martinez-Cruzado, J Tornin, L Santos, A Rodriguez, J García-Castro, ... Scientific reports 6 (1), 27878, 2016 | 59 | 2016 |
Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma J Tornin, L Martinez-Cruzado, L Santos, A Rodriguez, LE Núñez, P Oro, ... Oncotarget 7 (21), 30935, 2016 | 53 | 2016 |
FUS-CHOP promotes invasion in myxoid liposarcoma through a SRC/FAK/RHO/ROCK-dependent pathway J Tornin, F Hermida-Prado, RS Padda, MV Gonzalez, ... Neoplasia 20 (1), 44-56, 2018 | 43 | 2018 |
Exploring the use of cold atmospheric plasma to overcome drug resistance in cancer D Murillo, C Huergo, B Gallego, R Rodríguez, J Tornín Biomedicines 11 (1), 208, 2023 | 40 | 2023 |
Cold atmospheric plasma: a new strategy based primarily on oxidative stress for osteosarcoma therapy M Mateu-Sanz, J Tornín, MP Ginebra, C Canal Journal of clinical medicine 10 (4), 893, 2021 | 40 | 2021 |
Osteosarcoma tissue-engineered model challenges oxidative stress therapy revealing promoted cancer stem cell properties J Tornín, A Villasante, X Solé-Martí, MP Ginebra, C Canal Free Radical Biology and Medicine 164, 107-118, 2021 | 38 | 2021 |
Trabectedin and campthotecin synergistically eliminate cancer stem cells in cell-of-origin sarcoma models L Martinez-Cruzado, J Tornin, A Rodriguez, L Santos, E Allonca, ... Neoplasia 19 (6), 460-470, 2017 | 32 | 2017 |
Cold atmospheric plasma enhances doxorubicin selectivity in metastasic bone cancer M Mateu-Sanz, MP Ginebra, J Tornín, C Canal Free Radical Biology and Medicine 189, 32-41, 2022 | 25 | 2022 |
New chondrosarcoma cell lines with preserved stem cell properties to study the genomic drift during in vitro/in vivo growth V Rey, ST Menendez, O Estupiñan, A Rodriguez, L Santos, J Tornin, ... Journal of Clinical Medicine 8 (4), 455, 2019 | 25 | 2019 |
The SRC inhibitor dasatinib induces stem cell-like properties in head and neck cancer cells that are effectively counteracted by the mithralog EC-8042 F Hermida-Prado, MÁ Villaronga, R Granda-Díaz, N del-Río-Ibisate, ... Journal of Clinical Medicine 8 (8), 1157, 2019 | 22 | 2019 |
Mithramycin delivery systems to develop effective therapies in sarcomas Ó Estupiñán, E Niza, I Bravo, V Rey, J Tornín, B Gallego, ... Journal of nanobiotechnology 19, 1-21, 2021 | 15 | 2021 |
The multikinase inhibitor EC‐70124 synergistically increased the antitumor activity of doxorubicin in sarcomas O Estupiñan, L Santos, A Rodriguez, L Fernandez‐Nevado, P Costales, ... International Journal of Cancer 145 (1), 254-266, 2019 | 15 | 2019 |
Cold plasma and inhibition of STAT3 selectively target tumorigenicity in osteosarcoma J Tornín, M Mateu-Sanz, V Rey, D Murillo, C Huergo, B Gallego, ... Redox Biology 62, 102685, 2023 | 10 | 2023 |