| MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells N Xu, T Papagiannakopoulos, G Pan, JA Thomson, KS Kosik Cell 137 (4), 647-658, 2009 | 1368 | 2009 |
| CRISPR-mediated direct mutation of cancer genes in the mouse liver W Xue, S Chen, H Yin, T Tammela, T Papagiannakopoulos, NS Joshi, ... Nature 514 (7522), 380-384, 2014 | 918 | 2014 |
| MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells T Papagiannakopoulos, A Shapiro, KS Kosik Cancer research 68 (19), 8164-8172, 2008 | 903 | 2008 |
| Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer SM Davidson, T Papagiannakopoulos, BA Olenchock, JE Heyman, ... Cell metabolism 23 (3), 517-528, 2016 | 751 | 2016 |
| Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development JR Mayers, C Wu, CB Clish, P Kraft, ME Torrence, BP Fiske, C Yuan, ... Nature medicine 20 (10), 1193-1198, 2014 | 697 | 2014 |
| NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis SW Alvarez, VO Sviderskiy, EM Terzi, T Papagiannakopoulos, AL Moreira, ... Nature 551 (7682), 639-643, 2017 | 645 | 2017 |
| Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis R Romero, VI Sayin, SM Davidson, MR Bauer, SX Singh, SE LeBoeuf, ... Nature medicine 23 (11), 1362-1368, 2017 | 606 | 2017 |
| Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers JR Mayers, ME Torrence, LV Danai, T Papagiannakopoulos, ... Science 353 (6304), 1161-1165, 2016 | 578 | 2016 |
| Circadian rhythm disruption promotes lung tumorigenesis T Papagiannakopoulos, MR Bauer, SM Davidson, M Heimann, ... Cell metabolism 24 (2), 324-331, 2016 | 496 | 2016 |
| Nrf2 activation promotes lung cancer metastasis by inhibiting the degradation of Bach1 L Lignitto, SE LeBoeuf, H Homer, S Jiang, M Askenazi, TR Karakousi, ... Cell 178 (2), 316-329. e18, 2019 | 485 | 2019 |
| Rapid modelling of cooperating genetic events in cancer through somatic genome editing FJ Sánchez-Rivera, T Papagiannakopoulos, R Romero, T Tammela, ... Nature 516 (7531), 428-431, 2014 | 445 | 2014 |
| Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours J Garcia-Bermudez, L Baudrier, K La, XG Zhu, J Fidelin, VO Sviderskiy, ... Nature cell biology 20 (7), 775-781, 2018 | 412 | 2018 |
| Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing DG McFadden, T Papagiannakopoulos, A Taylor-Weiner, C Stewart, ... Cell 156 (6), 1298-1311, 2014 | 319 | 2014 |
| Lung adenocarcinoma distally rewires hepatic circadian homeostasis S Masri, T Papagiannakopoulos, K Kinouchi, Y Liu, M Cervantes, P Baldi, ... Cell 165 (4), 896-909, 2016 | 248 | 2016 |
| Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases T Papagiannakopoulos, D Friedmann-Morvinski, P Neveu, JC Dugas, ... Oncogene 31 (15), 1884-1895, 2012 | 219 | 2012 |
| Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer VI Sayin, SE LeBoeuf, SX Singh, SM Davidson, D Biancur, BS Guzelhan, ... elife 6, e28083, 2017 | 217 | 2017 |
| Lower airway dysbiosis affects lung cancer progression JCJ Tsay, BG Wu, I Sulaiman, K Gershner, R Schluger, Y Li, TA Yie, ... Cancer discovery 11 (2), 293-307, 2021 | 216 | 2021 |
| The cochaperone BAG2 sweeps paired helical filament-insoluble tau from the microtubule DC Carrettiero, I Hernandez, P Neveu, T Papagiannakopoulos, KS Kosik Journal of Neuroscience 29 (7), 2151-2161, 2009 | 198 | 2009 |
| In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma F Li, Q Huang, TA Luster, H Hu, H Zhang, WL Ng, A Khodadadi-Jamayran, ... Cancer discovery 10 (2), 270-287, 2020 | 174 | 2020 |
| Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment SA Kerk, T Papagiannakopoulos, YM Shah, CA Lyssiotis Nature Reviews Cancer 21 (8), 510-525, 2021 | 167 | 2021 |
Tyler JacksAdresse e-mail validée de breakthroughcancer.org
