Genes required for mycobacterial growth defined by high density mutagenesis CM Sassetti, DH Boyd, EJ Rubin Molecular microbiology 48 (1), 77-84, 2003 | 3068 | 2003 |
Genetic requirements for mycobacterial survival during infection CM Sassetti, EJ Rubin Proceedings of the National Academy of Sciences 100 (22), 12989-12994, 2003 | 1624 | 2003 |
Mycobacterial persistence requires the utilization of host cholesterol AK Pandey, CM Sassetti Proceedings of the National Academy of Sciences 105 (11), 4376-4380, 2008 | 1188 | 2008 |
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism JE Griffin, JD Gawronski, MA DeJesus, TR Ioerger, BJ Akerley, ... PLoS pathogens 7 (9), e1002251, 2011 | 1185 | 2011 |
Comprehensive identification of conditionally essential genes in mycobacteria CM Sassetti, DH Boyd, EJ Rubin Proceedings of the National Academy of Sciences 98 (22), 12712-12717, 2001 | 765 | 2001 |
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β BB Mishra, VAK Rathinam, GW Martens, AJ Martinot, H Kornfeld, ... Nature immunology 14 (1), 52-60, 2013 | 647 | 2013 |
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis MA DeJesus, ER Gerrick, W Xu, SW Park, JE Long, CC Boutte, EJ Rubin, ... MBio 8 (1), 10.1128/mbio. 02133-16, 2017 | 612 | 2017 |
Mutually dependent secretion of proteins required for mycobacterial virulence SM Fortune, A Jaeger, DA Sarracino, MR Chase, CM Sassetti, ... Proceedings of the National Academy of Sciences 102 (30), 10676-10681, 2005 | 504 | 2005 |
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform JM Rock, FF Hopkins, A Chavez, M Diallo, MR Chase, ER Gerrick, ... Nature microbiology 2 (4), 1-9, 2017 | 500 | 2017 |
RNA secondary structure and binding sites for gag gene products in the 5'packaging signal of human immunodeficiency virus type 1 J Clever, C Sassetti, TG Parslow Journal of virology 69 (4), 2101-2109, 1995 | 451 | 1995 |
The normalcy of dormancy: common themes in microbial quiescence ESC Rittershaus, SH Baek, CM Sassetti Cell host & microbe 13 (6), 643-651, 2013 | 385 | 2013 |
Metabolic regulation of mycobacterial growth and antibiotic sensitivity SH Baek, AH Li, CM Sassetti PLoS biology 9 (5), e1001065, 2011 | 358 | 2011 |
NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis AK Pandey, Y Yang, Z Jiang, SM Fortune, F Coulombe, MA Behr, ... PLoS pathogens 5 (7), e1000500, 2009 | 350 | 2009 |
Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34 C Sassetti, K Tangemann, MS Singer, DB Kershaw, SD Rosen The Journal of experimental medicine 187 (12), 1965-1975, 1998 | 347 | 1998 |
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations JE Griffin, AK Pandey, SA Gilmore, V Mizrahi, JD Mckinney, CR Bertozzi, ... Chemistry & biology 19 (2), 218-227, 2012 | 323 | 2012 |
Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis YJ Zhang, TR Ioerger, C Huttenhower, JE Long, CM Sassetti, ... Public Library of Science 8 (9), e1002946, 2012 | 296 | 2012 |
Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptide F Coulombe, M Divangahi, F Veyrier, L de Léséleuc, JL Gleason, Y Yang, ... Journal of Experimental Medicine 206 (8), 1709-1716, 2009 | 293 | 2009 |
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2 Y Yang, C Yin, A Pandey, D Abbott, C Sassetti, MA Kelliher Journal of Biological Chemistry 282 (50), 36223-36229, 2007 | 288 | 2007 |
Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis BB Mishra, RR Lovewell, AJ Olive, G Zhang, W Wang, E Eugenin, ... Nature microbiology 2 (7), 1-11, 2017 | 283 | 2017 |
Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis TR Ioerger, T O’Malley, R Liao, KM Guinn, MJ Hickey, N Mohaideen, ... PloS one 8 (9), e75245, 2013 | 277 | 2013 |