| Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach LG Hernández, H van Steeg, M Luijten, J van Benthem Mutation Research/Reviews in Mutation Research 682 (2-3), 94-109, 2009 | 297 | 2009 |
| Oxidative DNA damage and nucleotide excision repair JPM Melis, H van Steeg, M Luijten Antioxidants & redox signaling 18 (18), 2409-2419, 2013 | 277 | 2013 |
| How adverse outcome pathways can aid the development and use of computational prediction models for regulatory toxicology C Wittwehr, H Aladjov, G Ankley, HJ Byrne, J de Knecht, E Heinzle, ... Toxicological Sciences 155 (2), 326-336, 2017 | 176 | 2017 |
| Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in … I Moffat, NL Chepelev, S Labib, J Bourdon-Lacombe, B Kuo, JK Buick, ... Critical reviews in toxicology 45 (1), 1-43, 2015 | 166 | 2015 |
| Toxicogenomics directory of chemically exposed human hepatocytes M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ... Archives of toxicology 88, 2261-2287, 2014 | 151 | 2014 |
| Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not? S Fragki, H Dirven, T Fletcher, B Grasl-Kraupp, K Bjerve Gützkow, ... Critical reviews in toxicology 51 (2), 141-164, 2021 | 143 | 2021 |
| DNA methylation markers associated with type 2 diabetes, fasting glucose and HbA1c levels: a systematic review and replication in a case–control sample of the Lifelines study E Walaszczyk, M Luijten, AMW Spijkerman, MJ Bonder, HL Lutgers, ... Diabetologia 61 (2), 354-368, 2018 | 138 | 2018 |
| New approach methodologies in human regulatory toxicology–Not if, but how and when! S Schmeisser, A Miccoli, M von Bergen, E Berggren, A Braeuning, ... Environment international 178, 108082, 2023 | 132 | 2023 |
| Transgenic animal models in toxicology: historical perspectives and future outlook DR Boverhof, MP Chamberlain, CR Elcombe, FJ Gonzalez, RH Heflich, ... Toxicological sciences 121 (2), 207-233, 2011 | 119 | 2011 |
| Consideration of pathways for immunotoxicity of per-and polyfluoroalkyl substances (PFAS) V Ehrlich, W Bil, R Vandebriel, B Granum, M Luijten, B Lindeman, ... Environmental Health 22 (1), 19, 2023 | 111 | 2023 |
| Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non … MN Jacobs, A Colacci, R Corvi, M Vaccari, MC Aguila, M Corvaro, ... Archives of toxicology 94, 2899-2923, 2020 | 109 | 2020 |
| Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution S Rotter, A Beronius, AR Boobis, A Hanberg, J Van Klaveren, M Luijten, ... Critical reviews in toxicology 48 (9), 796-814, 2018 | 103 | 2018 |
| Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity L Fredriksson, S Wink, B Herpers, G Benedetti, M Hadi, H Bont, ... Toxicological sciences 140 (1), 144-159, 2014 | 100 | 2014 |
| Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014–2021) E Govarts, L Gilles, LR Martin, T Santonen, P Apel, P Alvito, E Anastasi, ... International Journal of Hygiene and Environmental Health 249, 114119, 2023 | 87 | 2023 |
| International regulatory needs for development of an IATA for non-genotoxic carcinogenic chemical substances MN Jacobs, A Colacci, K Louekari, M Luijten, BC Hakkert, M Paparella, ... Altex 33 (4), 359-392, 2016 | 85 | 2016 |
| A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe P Marx-Stoelting, G Rivière, M Luijten, K Aiello-Holden, N Bandow, ... Archives of toxicology 97 (3), 893-908, 2023 | 82 | 2023 |
| Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations KL Dearfield, BB Gollapudi, JC Bemis, RD Benz, GR Douglas, ... Environmental and molecular mutagenesis 58 (5), 264-283, 2017 | 82 | 2017 |
| Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data A Krebs, T Waldmann, MF Wilks, BMA van Vugt-Lussenburg, ... ALTEX-Alternatives to animal experimentation 36 (4), 682-699, 2019 | 77 | 2019 |
| Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology JA Harrill, MR Viant, CL Yauk, M Sachana, TW Gant, SS Auerbach, ... Regulatory Toxicology and Pharmacology 125, 105020, 2021 | 76 | 2021 |
| The role of XPC: implications in cancer and oxidative DNA damage JPM Melis, M Luijten, LHF Mullenders, H van Steeg Mutation Research/Reviews in Mutation Research 728 (3), 107-117, 2011 | 75 | 2011 |
