Cancer stem cells: From historical roots to a new perspective JP Capp Journal of oncology 2019, 2019 | 142 | 2019 |
The DNA polymerase λ is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells JP Capp, F Boudsocq, P Bertrand, A Laroche-Clary, P Pourquier, ... Nucleic acids research 34 (10), 2998-3007, 2006 | 136 | 2006 |
Stochastic gene expression, disruption of tissue averaging effects and cancer as a disease of development JP Capp Bioessays 27 (12), 1277-1285, 2005 | 91 | 2005 |
Identifying key questions in the ecology and evolution of cancer AM Dujon, A Aktipis, C Alix‐Panabières, SR Amend, AM Boddy, JS Brown, ... Evolutionary applications 14 (4), 877-892, 2021 | 86 | 2021 |
Involvement of DNA polymerase μ in the repair of a specific subset of DNA double-strand breaks in mammalian cells JP Capp, F Boudsocq, AG Besnard, BS Lopez, C Cazaux, JS Hoffmann, ... Nucleic acids research 35 (11), 3551-3560, 2007 | 73 | 2007 |
Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase β F Boudsocq, P Benaim, Y Canitrot, M Knibiehler, F Ausseil, JP Capp, ... Molecular Pharmacology 67 (5), 1485-1492, 2005 | 62 | 2005 |
The evolution and ecology of benign tumors J Boutry, S Tissot, B Ujvari, JP Capp, M Giraudeau, AM Nedelcu, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1877 (1), 188643, 2022 | 60 | 2022 |
Is There One Key Step in the Metastatic Cascade? AM Dujon, JP Capp, JS Brown, P Pujol, RA Gatenby, B Ujvari, ... Cancers 13 (15), 3693, 2021 | 42 | 2021 |
Natural yeast promoter variants reveal epistasis in the generation of transcriptional-mediated noise and its potential benefit in stressful conditions J Liu, H Martin-Yken, F Bigey, S Dequin, JM François, JP Capp Genome Biology and Evolution 7 (4), 969-984, 2015 | 41 | 2015 |
DNA polymerase β overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells Y Canitrot, JP Capp, N Puget, A Bieth, B Lopez, JS Hoffmann, C Cazaux Nucleic acids research 32 (17), 5104-5112, 2004 | 33 | 2004 |
Tissue disruption increases stochastic gene expression thus producing tumors: Cancer initiation without driver mutation JP Capp International Journal of Cancer 140 (11), 2408-2413, 2017 | 28 | 2017 |
Use of noise in gene expression as an experimental parameter to test phenotypic effects J Liu, JM François, JP Capp Yeast 33 (6), 209-216, 2016 | 28 | 2016 |
Group phenotypic composition in cancer JP Capp, J DeGregori, AM Nedelcu, AM Dujon, J Boutry, P Pujol, ... Elife 10, e63518, 2021 | 27 | 2021 |
Gene expression noise produces cell-to-cell heterogeneity in eukaryotic homologous recombination rate J Liu, JM François, JP Capp Frontiers in Genetics 10, 424105, 2019 | 26 | 2019 |
Multiple myeloma exemplifies a model of cancer based on tissue disruption as the initiator event JP Capp, R Bataille Frontiers in oncology 8, 355, 2018 | 23 | 2018 |
Stochastic gene expression stabilization as a new therapeutic strategy for cancer. JP Capp Bioessays: News and Reviews in Molecular, Cellular and Developmental Biology …, 2012 | 23 | 2012 |
Characterization of a natural mutator variant of human DNA polymerase λ which promotes chromosomal instability by compromising NHEJ G Terrados, JP Capp, Y Canitrot, M García-Díaz, K Bebenek, T Kirchhoff, ... PLoS One 4 (10), e7290, 2009 | 23 | 2009 |
Interplay between genetic, epigenetic, and gene expression variability: Considering complexity in evolvability JP Capp Evolutionary Applications 14 (4), 893-901, 2021 | 20 | 2021 |
Multiple myeloma as a bone disease? The tissue disruption-induced cell stochasticity (TiDiS) theory JP Capp, R Bataille Cancers 12 (8), 2158, 2020 | 20 | 2020 |
Tissue‐disruption‐induced cellular stochasticity and epigenetic drift: Common origins of aging and cancer? JP Capp, F Thomas Bioessays 43 (1), 2000140, 2021 | 17 | 2021 |