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Benjamin M J Owens
Benjamin M J Owens
EVP & Head of Corporate Development
Adresse e-mail validée de immedica.com
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The alarmin IL-33 promotes regulatory T-cell function in the intestine
C Schiering, T Krausgruber, A Chomka, A Fröhlich, K Adelmann, ...
Nature 513 (7519), 564-568, 2014
10572014
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease
NR West, AN Hegazy, BMJ Owens, SJ Bullers, B Linggi, S Buonocore, ...
Nature medicine 23 (5), 579-589, 2017
7692017
Circulating and tissue-resident CD4+ T cells with reactivity to intestinal microbiota are abundant in healthy individuals and function is altered during inflammation
AN Hegazy, NR West, MJT Stubbington, E Wendt, KIM Suijker, A Datsi, ...
Gastroenterology 153 (5), 1320-1337. e16, 2017
3392017
The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release
O Brain, BMJ Owens, T Pichulik, P Allan, E Khatamzas, A Leslie, ...
Immunity 39 (3), 521-536, 2013
2232013
Use of siltuximab in patients with COVID-19 pneumonia requiring ventilatory support
G Gritti, F Raimondi, D Ripamonti, I Riva, F Landi, L Alborghetti, M Frigeni, ...
1302020
Intestinal stromal cells in mucosal immunity and homeostasis
BMJ Owens, A Simmons
Mucosal immunology 6 (2), 224-234, 2013
1272013
IL-6 signalling pathway inactivation with siltuximab in patients with COVID-19 respiratory failure: an observational cohort study
G Gritti, F Raimondi, D Ripamonti, I Riva, F Landi, L Alborghetti, M Frigeni, ...
Medrxiv, 2020.04. 01.20048561, 2020
942020
IL-10-Producing Th1 Cells and Disease Progression Are Regulated by Distinct CD11c+ Cell Populations during Visceral Leishmaniasis
BMJ Owens, L Beattie, JWJ Moore, N Brown, JL Mann, JE Dalton, ...
PLoS pathogens 8 (7), e1002827, 2012
752012
The oncostatin M‐stromal cell axis in health and disease
NR West, BMJ Owens, AN Hegazy
Scandinavian Journal of Immunology 88 (3), e12694, 2018
692018
Siltuximab downregulates interleukin-8 and pentraxin 3 to improve ventilatory status and survival in severe COVID-19
G Gritti, F Raimondi, B Bottazzi, D Ripamonti, I Riva, F Landi, L Alborghetti, ...
Leukemia 35 (9), 2710-2714, 2021
592021
CD90+ Stromal Cells are Non-Professional Innate Immune Effectors of the Human Colonic Mucosa
BMJ Owens, TAM Steevels, M Dudek, D Walcott, MY Sun, A Mayer, ...
Frontiers in immunology 4, 307, 2013
592013
Inflammation, innate immunity, and the intestinal stromal cell niche: opportunities and challenges
BMJ Owens
Frontiers in immunology 6, 319, 2015
582015
Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice
JE Dalton, A Maroof, BMJ Owens, P Narang, K Johnson, N Brown, ...
The Journal of clinical investigation 120 (4), 1204-1216, 2010
542010
B cell: T cell interactions occur within hepatic granulomas during experimental visceral leishmaniasis
JWJ Moore, L Beattie, JE Dalton, BMJ Owens, A Maroof, MC Coles, ...
PLoS One 7 (3), e34143, 2012
382012
Antiviral activity of bone morphogenetic proteins and activins
LA Eddowes, K Al-Hourani, N Ramamurthy, J Frankish, HT Baddock, ...
Nature microbiology 4 (2), 339-351, 2019
352019
Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis
MJW Kain, BMJ Owens
Immunology 140 (1), 12-21, 2013
352013
Interferon Regulatory Factor 7 Contributes to the Control of Leishmania donovani in the Mouse Liver
L Beattie, R Phillips, N Brown, BMJ Owens, N Chauhan, JE Dalton, ...
Infection and immunity 79 (3), 1057-1066, 2011
272011
IRF7 Regulates TLR2-Mediated Activation of Splenic CD11chi Dendritic Cells
BMJ Owens, JWJ Moore, PM Kaye
PloS one 7 (7), e41050, 2012
212012
ADOPT: intrinsic protein disorder prediction through deep bidirectional transformers
I Redl, C Fisicaro, O Dutton, F Hoffmann, L Henderson, BMJ Owens, ...
NAR Genomics and Bioinformatics 5 (2), lqad041, 2023
192023
Stromal cell induction of regulatory dendritic cells
BMJ Owens, PM Kaye
Frontiers in immunology 3, 262, 2012
172012
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