Suivre
Caelan Radford
Caelan Radford
Staff Scientist, Fred Hutch Cancer Center
Adresse e-mail validée de fredhutch.org
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A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike
B Dadonaite, KHD Crawford, CE Radford, AG Farrell, CY Timothy, ...
Cell 186 (6), 1263-1278. e20, 2023
1132023
An experimental phylogeny to benchmark ancestral sequence reconstruction
RN Randall, CE Radford, KA Roof, DK Natarajan, EA Gaucher
Nature communications 7 (1), 12847, 2016
852016
A biophysical model of viral escape from polyclonal antibodies
TC Yu, ZT Thornton, WW Hannon, WS DeWitt, CE Radford, FA Matsen IV, ...
Virus Evolution 8 (2), veac110, 2022
212022
Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning
CE Radford, P Schommers, L Gieselmann, KHD Crawford, B Dadonaite, ...
Cell Host & Microbe 31 (7), 1200-1215. e9, 2023
182023
Identification of coagulation factor IX variants with enhanced activity through ancestral sequence reconstruction
KA Knight, CW Coyle, CE Radford, ET Parker, A Fedanov, JM Shields, ...
Blood Advances 5 (17), 3333-3343, 2021
102021
Molecular coevolution of coagulation factor VIII and von Willebrand factor
PM Zakas, CW Coyle, A Brehm, M Bayer, B Solecka-Witulska, CE Radford, ...
Blood Advances 5 (3), 812-822, 2021
72021
A biophysical model of viral escape from polyclonal antibodies. Virus Evol. 8, veac110
TC Yu, ZT Thornton, WW Hannon, WS DeWitt, CE Radford, FA Matsen, ...
62022
An experimental phylogeny to benchmark ancestral sequence reconstruction. Nat Commun 7: 12847
RN Randall, CE Radford, KA Roof, DK Natarajan, EA Gaucher
62016
Dynamics and durability of HIV-1 neutralization are determined by viral replication
P Schommers, DS Kim, M Schlotz, C Kreer, R Eggeling, A Hake, ...
Nature Medicine 29 (11), 2763-2774, 2023
42023
Functional and antigenic landscape of the Nipah virus receptor binding protein
BB Larsen, T McMahon, JT Brown, Z Wang, CE Radford, JE Crowe Jr, ...
bioRxiv, 2024
22024
Ancestral Sequence Reconstruction of Von Willebrand Factor Reveals Highly Conserved Structure/Function
PM Zakas, C Radford, C Brown, C Dwyer, CB Doering, EA Gaucher, ...
Blood 130, 240, 2017
12017
von Willebrand Factor Proteins for Treating Bleeding Disorders
P Zakas, D Lillicrap, C Doering, E Gaucher, C Radford, HT Spencer
US Patent App. 18/883,537, 2025
2025
Comprehensive maps of escape mutations from antibodies 10-1074 and 3BNC117 for Envs from two divergent HIV strains
CE Radford, JD Bloom
bioRxiv, 2025.01. 30.635715, 2025
2025
Von Willebrand factor proteins for treating bleeding disorders
P Zakas, D Lillicrap, C Doering, E Gaucher, C Radford, HT Spencer
US Patent 12,116,399, 2024
2024
Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations
AK Aditham, CE Radford, CR Carr, N Jasti, NP King, JD Bloom
bioRxiv, 2024.12. 17.628970, 2024
2024
Nucleic acids encoding clotting factor variants and their use
C Doering, HT Spencer, E Gaucher, C Radford
US Patent 11,633,504, 2023
2023
A lentiviral vector deep mutational scanning system for studying virus evolution and escape from neutralization by antibodies and polyclonal serum
C Radford
University of Washington, 2023
2023
Cell-stored barcoded deep mutational scanning libraries and uses of the same
J Bloom, AS Dingens, K Dusenbury, C Radford
US Patent App. 17/281,540, 2021
2021
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