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Michael J. Castle
Michael J. Castle
Adresse e-mail validée de ucsd.edu
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Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey
LH Vandenberghe, P Bell, AM Maguire, CN Cearley, R Xiao, R Calcedo, ...
Science translational medicine 3 (88), 88ra54-88ra54, 2011
2692011
Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport
MJ Castle, ZT Gershenson, AR Giles, ELF Holzbaur, JH Wolfe
Human gene therapy 25 (8), 705-720, 2014
2012014
Controlling AAV tropism in the nervous system with natural and engineered capsids
MJ Castle, HT Turunen, LH Vandenberghe, JH Wolfe
Gene Therapy for Neurological Disorders: Methods and Protocols, 133-149, 2016
1942016
Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment
MJ Castle, E Perlson, ELF Holzbaur, JH Wolfe
Molecular Therapy 22 (3), 554-566, 2014
1212014
Postmortem analysis in a clinical trial of AAV2-NGF gene therapy for Alzheimer's disease identifies a need for improved vector delivery
MJ Castle, FC Baltanás, I Kovacs, AH Nagahara, D Barba, MH Tuszynski
Human gene therapy 31 (7-8), 415-422, 2020
1012020
Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion
MJ Castle, Y Cheng, A Asokan, MH Tuszynski
Science Advances 4 (11), eaau9859, 2018
472018
Intersectional targeting of defined neural circuits by adeno‐associated virus vectors
CA Weinholtz, MJ Castle
Journal of neuroscience research 99 (4), 981-990, 2021
232021
In situ hybridization for detection of AAV-mediated gene expression
JE Hunter, BL Gurda, SY Yoon, MJ Castle, JH Wolfe
Adeno-Associated Virus Vectors: Design and Delivery, 107-122, 2019
112019
Adeno-Associated Virus Vectors
MJ Castle
Springer: http://doi.org/10.1007/978-1-4939-9139-6, 2019
22019
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