Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey LH Vandenberghe, P Bell, AM Maguire, CN Cearley, R Xiao, R Calcedo, ... Science translational medicine 3 (88), 88ra54-88ra54, 2011 | 269 | 2011 |
Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport MJ Castle, ZT Gershenson, AR Giles, ELF Holzbaur, JH Wolfe Human gene therapy 25 (8), 705-720, 2014 | 201 | 2014 |
Controlling AAV tropism in the nervous system with natural and engineered capsids MJ Castle, HT Turunen, LH Vandenberghe, JH Wolfe Gene Therapy for Neurological Disorders: Methods and Protocols, 133-149, 2016 | 194 | 2016 |
Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment MJ Castle, E Perlson, ELF Holzbaur, JH Wolfe Molecular Therapy 22 (3), 554-566, 2014 | 121 | 2014 |
Postmortem analysis in a clinical trial of AAV2-NGF gene therapy for Alzheimer's disease identifies a need for improved vector delivery MJ Castle, FC Baltanás, I Kovacs, AH Nagahara, D Barba, MH Tuszynski Human gene therapy 31 (7-8), 415-422, 2020 | 101 | 2020 |
Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion MJ Castle, Y Cheng, A Asokan, MH Tuszynski Science Advances 4 (11), eaau9859, 2018 | 47 | 2018 |
Intersectional targeting of defined neural circuits by adeno‐associated virus vectors CA Weinholtz, MJ Castle Journal of neuroscience research 99 (4), 981-990, 2021 | 23 | 2021 |
In situ hybridization for detection of AAV-mediated gene expression JE Hunter, BL Gurda, SY Yoon, MJ Castle, JH Wolfe Adeno-Associated Virus Vectors: Design and Delivery, 107-122, 2019 | 11 | 2019 |
Adeno-Associated Virus Vectors MJ Castle Springer: http://doi.org/10.1007/978-1-4939-9139-6, 2019 | 2 | 2019 |